Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69215	Irsogladine	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	142	HDAC9; SOX9; PRKDC; BRD2; IRF1; BBX; HMGB1; NPM1; KLF10; NPAS2; RBBP7; NONO; MYC; YBX1; TRIM32; CREB5; ZNF248; ZBTB25; APEX1; TFEB; HLTF; MAGED1; JARID2; CCNC; ZNF672; SREBF1; HMG20B; PPARGC1A; NCOR2; ZNF23; ZNF226; CITED1; TAF1D; BHLHE41; NFIB; RLF; TDRD3; TRIP4; HIRA; TBX19; PBRM1; BCL3; TBL1XR1; ZMYND8; IRF8; MAZ; FOXO4; KAT7; HDAC1; VGLL4; NR2F2; SMARCE1; CLOCK; GABPB1; TCF7; GATA3; TBP; PCGF2; NR3C2; DNMT3B; SCAND1; DDX5; DNAJC1; RHOA; XBP1; CENPF; NFKBIA; ZNF536; HOXD1; FLNA; SIX2; ETV5; ST18; MED1; GATAD2A; PTTG1; JUNB; PSPC1; NR2C1; FOXC1; EZH2; PAX8; HMGN3; ATF3; SMAD2; HEY1; ATF6; MYCBP; SMARCA1; SFMBT1; NFIL3; CCNA2; ZNF721; NEDD8; MED6; RORA; JUN; DMTF1; SNAI2; ID2; HIVEP2; DRAP1; SATB2; EGR3; NRBF2; SSX1; SAP30; JUND; CTR9; RFX5; SAP18; SMARCA2; POLR2A; FHL2; BMI1; CEBPB; TRPS1; BRD4; TOX3; CEBPA; MAFF; FOSB; TBL1X; NR1H2; SSBP2; DAXX; ZNF160; SPEN; MED24; CREB3L2; PLAGL1; MSX1; FOXJ3; ZFP36L2; TLE1; PHIP; KLF2; EMX2; TSC22D1; ZNF91; HES1; ASCL1
Down-regulation	101	BNC2; CDK9; ZNF200; STAT2; CRYM; HBP1; SUMO1; TFAP2A; ETV6; FOXE1; REST; ZNF557; GLI2; FOXL2; ARID5B; BNC1; PBX1; TGIF2; RB1; EHF; TRIM22; BCL11A; OSR2; TGIF1; GATA6; ZNF217; ZBED1; ETV1; ZNF586; ZNF573; SOX11; TCF21; IRF6; TCF25; VDR; FOXF2; TEAD4; HINFP; WWP1; ZSCAN31; STAT4; TOPORS; BASP1; OVOL2; ZNF266; MYBL2; SSBP3; ZNF329; FOS; ZNF175; ZFPM2; DACH1; HMGA1; MYCL; HLX; YEATS4; ZNF423; ZNF350; ZNF232; ZNF551; IRF9; ZSCAN18; TULP3; NFATC3; PITX2; ZNF426; PSMC3; OLIG2; NPAT; NR2F1; EPAS1; TCEB2; ZFP36L1; STAT1; PBX3; MKL2; POU2AF1; ARNTL2; SHOX2; SOX17; FOXM1; TULP4; SMAD3; HOXB2; DLX2; TCF4; MYB; VPS72; AEBP1; IRF4; NR4A2; NFAT5; MAFB; ZIC1; CEBPD; ID4; FOXF1; ZBED2; THAP11; KDM5A; ZBTB18