Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69213	Purmorphamine	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	213	HOXC6; SND1; TRIM32; MYC; EDF1; MAGED1; TP53; SIX1; REPIN1; BCLAF1; ZMIZ2; ELF1; PPARGC1A; MLX; ITGB3BP; SIX2; TCF12; BATF; HNRNPD; BRD2; RUVBL2; VGLL4; YBX1; TBP; HOXC4; FOXD1; PRKDC; USF2; ELK3; NFIB; SMARCE1; GTF2IRD1; AFF1; NPAS2; EYA1; TLE2; MTDH; MAZ; DNAJC1; NELFB; PA2G4; CCNC; TAF10; BHLHE40; HLTF; SCAND1; POU3F1; BRPF1; ATF4; TRIM28; NUP62; ETV5; KLF10; PAX8; CASZ1; MSX1; CTR9; BMI1; DNMT3B; NPM1; ORC2; POU4F1; PBRM1; TFCP2L1; BBX; JARID2; PDLIM1; PMF1; UBE2I; BAZ1B; STAT5A; PPARG; SREBF1; RBBP7; IRF1; RNF10; RHOA; SOX9; STAT5B; NCOA4; EED; GTF3A; ZNF672; CRK; HMGN3; FOXJ1; BRD8; BIRC2; UIMC1; NEDD8; ELK1; RELB; HSBP1; HDAC6; ZNF146; FOXO3; RNF141; ZNF536; ZBTB40; HEY1; FOXO4; CEBPA; MYCBP; SUV39H1; ZNF646; BCL3; POLR2A; TRIP4; DRAP1; DDX54; HIVEP2; CREB5; TBPL1; ZNF410; TCF15; CLOCK; PURA; PHF8; KLF2; HDAC1; NFKB1; RB1; DDX5; SMARCA1; GABPB1; NFKBIA; USP22; PHOX2A; SNW1; XBP1; KDM4A; SOX4; MED1; SETD3; PCGF1; RBM14; ZNF226; FOSL1; KAT7; RBBP4; HMGB1; ZNF593; MTA1; NRIP1; FHL2; BATF3; SMARCA2; KDM5D; SMARCA4; CTNNB1; NKX3-1; STAT3; COPS2; HDAC7; LPIN2; CBFB; PCGF2; SAFB2; KDM2A; NCOR2; JUNB; NAB1; CNOT1; TRIP6; CCNA2; DEK; GATAD2A; PITX1; BTF3; MEOX2; SMAD1; PIAS3; ARNTL2; PCBD1; SFPQ; ENY2; JUND; PRRX2; ATF6; ECD; MAFF; ZBTB38; MED24; NRBF2; MEOX1; KLF6; TLE1; PHF20; IRF4; EZH2; IKBKAP; PLAGL1; RFX5; CEBPB; MED6; TWIST1; CREB3L1; CARHSP1; FLNA; FOSB; CALR; ENO1; PIR; ABL1; ZNF721; SOX10; ATF5; LEF1; KAT6B; WWTR1; NKX2-2; ZIC1; RUNX3
Down-regulation	221	E2F8; BRWD1; ZNF107; MEIS1; TFAP2A; GATA6; BRD7; DNMT1; OSR2; ZNF200; DACH1; PBX1; SOX11; FOXL2; TCF21; BRIP1; FOXI1; HOXA1; CSDC2; ZNF467; ID4; ZNF623; ZFPM2; MYCL; SPDEF; ZNF492; PRDM10; ZNF273; ZNF75D; HIC2; MNDA; CDK2; SUV39H2; TFDP1; KLF11; RSF1; TCEA2; GFI1; NR5A2; NR2F6; ZEB1; SOX13; ERBB4; BCL11A; CREB3; ZBED2; ZIC3; NR2F1; FOXE1; ZNF225; HOXB5; SCAI; TBX3; MED14; ZNF74; ARID5B; MBD4; ZFX; NR4A2; ZNF180; BACH1; FOXN3; PAXBP1; ZNF141; MEIS2; VDR; RCOR3; PBX3; ZNF223; MYBL1; ZXDC; IRF6; ZNF124; SOX17; SMAD4; ZBTB44; CBFA2T3; PRDM2; PGR; ZNF667; ZNF695; PSMC3; WDR77; SKI; ZNF557; CNOT3; ZNF257; ZNF117; SOX18; ESRRG; ZNF652; NAB2; RARG; ZBTB6; GRHL2; ZNF140; ATN1; CAMTA2; ZNF682; ZNF232; ARL2BP; CREB1; ZNF132; RNF138; ZNF573; THAP10; ZFHX3; ZNF195; RREB1; PLAG1; NFX1; ZNF350; ZNF331; PAWR; PEX14; ZNF589; SUZ12; ZNF586; HBP1; ZSCAN18; NCOA1; KAT2A; ZNF112; TEAD4; DBP; SP2; HINFP; TTF2; MED17; WNT4; TBL1X; TRPS1; IRF9; FOXM1; ZNF211; FOXF2; SMARCD3; ZNF532; NANOG; SP140L; ZNF43; TCF7L1; ZNF304; NR4A1; SOX3; ZNF268; PEG3; KLF13; NPAT; RERE; SOX2; REL; ELF4; HIVEP1; NR4A3; JAK2; HMGA2; SNAI2; PROX1; CERS4; TULP3; BACH2; CARF; TAF9; RBBP8; CDK8; MYBL2; NFATC3; WT1; FOXK2; CBFA2T2; HHEX; NLK; ZNF33B; KAT6A; ZNF426; NCOA2; PITX2; L3MBTL1; ID3; NFE2L3; FOXF1; ESR1; HLX; NR1H2; EGR2; TRIM29; ARID1A; ST18; ZNF83; CUX2; TAF9B; TCF7L2; ZNF131; DLX2; TAL1; INSR; HMGB3; TFEC; ELF5; CHD7; CREB3L2; ARID4B; OLIG2; STAT4; SHOX2; JUP; ASCL1; HOXB2; ZNF512B; ZNF264; PAX5; CTBP2; NKX2-1; MYB; VPS72; AEBP1; TOX; THAP11; EMX2; POU2AF1