Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69212	Jak3-inhibitor-i	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	111	TCFL5; PRKDC; ZNF281; TBL1XR1; MAZ; MEF2A; MAFG; SP110; TOX3; GTF3A; SIM1; BRD2; HOXB7; YBX1; COPS5; ING2; SIX2; REPIN1; HOXB6; CEBPG; NFATC3; MSL3; TOB1; CREB5; MXD4; MEOX1; BATF; NR3C2; SMAD1; CBX7; SND1; HOXC4; BCL11B; FOXD1; SPIB; TAF12; ZNF672; RHOA; CLOCK; TAF1D; NR1I2; HLF; SCAND1; CAMTA1; NR2F2; SMARCC2; NR1H3; MLXIPL; RNF138; HMG20B; ZHX2; ELK3; CEBPA; NFIB; TSC22D3; TCEA1; EDF1; MED24; APEX1; MTDH; TCEB2; RSF1; ZEB2; MSX1; FOXO4; ETV5; HDAC7; MBD2; MLXIP; RFX5; ZNF593; LPIN2; SNAI2; CREB3L1; NEDD8; ATF6; SMAD2; TCF4; PPARGC1A; ID2; RBM14; SSX1; BIRC2; ZBTB16; TP63; PRRX1; BHLHE41; KLF2; DDX5; CEBPB; ATF3; CARHSP1; MAFB; ZBTB18; POU4F1; DRAP1; KLF4; KLF6; MED1; IRF7; KLF5; RUNX3; FOSB; ERBB2; ZIC1; ARID4B; ASCL1; TLE1; THAP11; KAT6B; TRIB3
Down-regulation	140	TCEA2; SPDEF; BNC2; PBX1; MEIS1; TFDP1; PBX3; TRIM25; ZBTB43; DNMT1; HBP1; ZNF443; ETS1; BRD7; PRDM1; FOXF2; TGIF1; EGR1; KLF11; ZNF665; TBX21; NFX1; PAXBP1; SETD2; HIC2; TDP2; CDK8; TCF21; CREB1; SOX2; IRF6; NR2F1; LIN28A; SOX13; IKZF1; STAT1; KDM5D; ZNF467; BACH1; CREM; ATN1; PCGF3; ZNF140; GATA6; MZF1; CHD8; ZNF562; SOX17; ZNF331; ZSCAN18; TRRAP; ID4; ZNF131; AEBP1; FOXL2; NKX3-1; ARID3B; EGR2; ZNF266; TEAD4; ZEB1; ZNF274; PLAG1; SMARCD3; FUBP1; BRD3; CBFA2T2; ZNF589; PMS1; AHR; TFAP2C; ZNF586; ZNF175; SMARCC1; RYBP; SUPT3H; NCOA3; REL; ELF3; AGO2; ZNF606; ZNF177; ZNF552; TULP3; ZSCAN31; NAB1; SMAD6; RB1; RAD21; RUNX1; SIM2; TBX3; TRPS1; HMGB3; HOXB13; FOXF1; NCOA1; NFKB2; LYL1; SERTAD2; TBPL1; ZNF217; CERS4; BATF3; ST18; ZNF532; CEBPD; NR4A3; MEIS2; BCL11A; SHOX2; ZMIZ1; ZNF43; SOX9; ZNF134; HES1; ZNF426; ERBB4; NR1H2; TULP4; DLX2; ZBED2; ZBTB38; FOXC1; STAT3; TAL1; FOXM1; KDM5A; ZFP36L1; STAT4; PSIP1; MYB; ZNF232; KDM5B; MYRF; SSBP2; PCGF2; WT1; ZNF264; ESR1