Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69198	Ponalrestat	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	150	NFKBIB; HOXC6; HOXA10; MAFG; BATF; HOXC10; CEBPG; TP53; BAZ1A; NCOR1; BRD2; EDF1; SIX2; NFIB; TRIM32; HTATIP2; ASXL1; PRDM8; ELF1; NR2E1; PRKDC; SOX9; TOX3; NR1H3; PRPF6; PITX2; MEF2C; PA2G4; UBE2I; ZBTB32; HMGB1; ZNF593; NFATC3; FOXD1; TRIM28; LHX1; KAT8; NR1I2; AATF; NPM1; HSF1; EYA1; HOXA7; RORA; TAF10; CTR9; KDM2A; HOXA11; HOXC4; DNAJC1; TCF12; CLOCK; SOX4; ZNF267; BRPF1; SERTAD2; UIMC1; PSPC1; PRRX2; ZBTB16; ING3; TAF1D; BMI1; CDYL; PHF20; HDAC7; PLAGL2; HMG20B; TBL1XR1; KMT2A; RUVBL2; BRD8; NCOA6; SMARCB1; LPIN2; HIVEP2; TCEA1; TWIST1; DDIT3; SFMBT1; DDX54; XBP1; HOXB9; TCF3; KLF5; CARHSP1; SIM2; ZNF226; PAX8; PAX6; MEOX1; GATAD2A; AFF1; GLI1; TCF15; FOXO3; NUP62; SCAND1; BHLHE40; ZKSCAN1; JUND; DNMT3B; DMTF1; PPARGC1A; RFX5; MAFF; ZNF430; HLTF; FOXK2; MYCBP; NRBF2; GABPB1; NEDD8; ORC2; ZNF721; WWTR1; CD3D; TSC22D4; RBM14; ENO1; PLAGL1; NFIL3; TGFB1; IKBKAP; YBX1; ZIC1; HMGN3; ATF3; BATF3; PRRX1; MED6; DRAP1; TCEB2; PAX5; TFDP2; ASH2L; POLR2A; ERBB2; DEK; MED1; STAT5A; ZNF160; CEBPA; SPEN; KAT6B; PSIP1; HES1; TLE1; EMX2; TRIB3
Down-regulation	152	BNC2; PBX1; STAT2; ZNF467; EHF; BBX; ISL1; CDK9; CREBL2; ZFPM2; ZNF286A; MNDA; ZNF492; NR4A2; HOXB13; HEY2; PHF2; SOX11; HIVEP1; TFAP2A; ZNF835; TCF21; MYCL; NANOG; ELK4; ZIC3; SNAI2; TFAP2C; ETS1; ZNF331; TCEA2; TAF9; LIN28A; ZNF107; FOXF1; PLAG1; ARL2BP; ZNF528; MDM4; STAT1; SOX2; NR2F1; SOX18; ZNF215; ZKSCAN8; ZNF586; HOXB6; ID4; BRCA1; ADNP2; SOX17; TFDP1; HLX; BACH1; FOXN3; WDHD1; ZNF623; FOXE1; ATN1; SSX1; FOXJ2; SOX13; POU5F1B; KLF4; DDX17; ZNF266; NR4A1; TAF9B; FOXF2; ZNF175; CREM; MEIS2; ZNF274; AR; ID1; SUZ12; HEY1; EYA2; KLF9; NAB1; ZNF134; CREB1; JUP; THAP10; NR4A3; MYT1L; ZSCAN18; TERF2; CBFA2T3; BCL11A; ZNF529; ZNF136; ESRRG; FOXM1; INSM1; NFE2L3; IRF9; ZNF532; TEAD4; GATA6; ZNF43; FOXA1; ZNF589; NCOA3; PAXBP1; MYRF; ZBTB38; MITF; PITX1; ZNF131; PHOX2B; SMAD1; SMAD6; MAF; TBX3; ID3; AHR; NR1H2; BACH2; SUB1; IRF4; TULP3; CITED2; EPAS1; TBX2; LOXL2; SMARCA4; ZNF232; EGR2; KDM5B; BASP1; ZBTB18; NKX2-2; INSR; PIR; FOSB; CTBP2; PHIP; MYB; ZBED2; IFI16; KDM5D; POU2AF1; WT1; PEG3; THAP11; TSC22D1; MAFB; PBX3; ELF5; KDM5A; SATB1