Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69091	Flunarizine	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	IKZF1; REPIN1; MYC; PURA; TP53; ARNTL; CREB5; TCF12; CTR9; TLE2; ATF4; TRIM28; BAZ1A; AFF1; CARHSP1; NPAS2; ZNF146; BRD8; RNF10; KLF12; AES; TRIM32; IRF1; HMG20B; HLTF; TAF10; BCL3; BRD2; CEBPG; ING3; NELFB; NFE2; VGLL4; EDF1; YBX1; USF2; BHLHE40; ZMIZ2; ELK3; FOXO4; SIX2; ZNF226; TRIP6; ZNF212; DNMT3B; BRPF1; ORC2; RUVBL2; DRAP1; NEDD8; BASP1; RBBP5; PLAGL1; TP63; HEY2; SCAND1; SMARCA1; PITX1; CD3D; GATA3; HDAC1; BAZ1B; TBP; SMARCE1; BIRC2; MYCBP; MAFB; TRIP4; SOX15; URI1; PPP1R13L; SCMH1; XBP1; SOX9; CRK; ETV5; MSX1; NRBF2; JUNB; TBL1XR1; CALR; RUNX3; SATB2; CDYL; DNAJC1; LPIN2; NCOA4; SP100; IRF2; PRRX1; SAFB2; HOXA5; TBPL1; EED; RBM14; ZBTB11; BRD4; RUNX1; BRF2; NFKBIA; CEBPA; MED1; CCNA2; TADA3; TAF1D; SNAI2; CREB3L1; EZH2; SIM2; JARID2; TCERG1; KLF1; ELF3; DEK; LITAF; FOXO3; HIVEP2; MED6; CEBPB; BMI1; FOSL1; ID2; RORA; JUND; MAFF; MEOX2; FOXJ3; SMARCA4; POLR2A; ZBTB38; PRRX2; BTG1; SATB1; TSC22D1; FOXG1; SSBP2; ABL1; KAT6B; ENO1; KDM5D; PSIP1; WWTR1; ID1; ESR1; EMX2; THAP11; HES1; ASCL1
Down-regulation	165	FOXI1; TFAP2A; BRD7; ARL2BP; GLI2; OSR2; FUBP1; GATA6; NR4A2; VDR; BNC2; KLF11; BRWD1; CDK9; TCF21; HMGB2; PBX3; NR4A1; PBX1; HIC2; ADNP2; WDR77; EMX1; FOXE1; FOXA2; ZFPM2; NHLH1; ZBED2; ETS1; ZIC3; CDK2; CBL; FOXL2; POLR3C; BRCA1; NAB2; SUZ12; ID4; VGLL1; ILF2; FOXN3; HIRA; MYBL2; ZNF135; MECP2; ZNF467; RNF138; CHD7; KAT6A; ZNF117; EGR2; IRF6; PEG3; NFYB; TFDP1; KLF9; SOX2; ZSCAN18; EHF; CCNH; EGR4; NR4A3; TRPS1; SMARCB1; DACH1; WT1; HIPK2; NR2F1; HOXB13; SRF; SMARCC1; MEIS2; SOX13; ZNF141; RAD21; BRIP1; MAF; XRCC6; PLAG1; ZNF274; ZNF34; ESRRG; PCGF3; TCEA2; MYCL; NANOG; NCOA1; PRDM1; HOXD3; NKX2-1; FOXO1; NFE2L3; MYBL1; DLX2; ZNF215; WNT4; RBL2; GFI1; MEIS1; HLX; ZNF665; TRRAP; ZNF331; SOHLH2; ARRB1; SOX3; SP3; HOXB6; NCOA2; SOX11; JAK2; ZNF711; ZNF586; ZNF165; LHX6; HMGXB4; KLF13; SSBP3; CREB3L2; ISL1; TOX3; PSMC3; SKI; CUX2; MKL2; TBX2; TFAP2C; ZSCAN31; NFATC1; IRF9; CHD9; FOXF2; ST18; TAF9B; CBFA2T3; MYRF; NFE2L2; ZNF217; ZNF589; MYCN; FOXC1; KDM5B; SMAD3; NFATC3; NR1H2; ZNF232; ATF3; ARID4B; YBX3; FOXM1; SMAD6; TBX3; MYB; AHR; BHLHE41; ZNF652; HIPK3; FOXF1; ID3; ZBTB18; POU2AF1; EGR3; ZNF512B; TOX; KDM5A