Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69083	Saquinavir	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	211	IRX5; NR1H3; PRKDC; TP53; TBL1XR1; ARNTL; MTA1; CREBZF; SOX4; BRCA1; ZNF184; LIMD1; PRDM2; DDX17; TFEB; MAGED1; PAX5; RXRA; FOXN3; NCOA4; REPIN1; SOX5; ELF1; SATB2; SERTAD2; SIX1; IRF1; ZNF107; HMGA1; KDM5D; NR3C2; MSC; ZEB2; CUX1; TRIM32; KLF10; SND1; TDRD3; SOX10; NFYC; EGR2; HABP4; RBBP5; ENO1; RNF10; TFCP2L1; ZNF236; CLOCK; LZTS1; NPAS2; BRD2; NRBF2; ZNF516; TRAK1; BLM; SPI1; ZNF623; MNAT1; ZNF248; MAF; NFATC1; IRF5; HDAC6; SOX12; HOXC4; PURA; ZHX3; KMT2B; SMARCA2; SIM2; ZNF3; KDM4A; SP140; FOXC1; HDAC4; ZNF23; BAZ1B; SOX9; MYC; HLF; LMCD1; MLX; BATF; DMRT1; NFIB; SKI; CALR; CTNNB1; KLF4; MLXIP; EGR3; ZNF226; JARID2; PGR; RARA; TSG101; HMGB1; MAZ; NFE2; PPARG; CDYL; TOX3; CREB5; NSD1; MBD4; RHOA; ZNF580; SREBF2; ARNT; NFKBIA; ZNF573; NPM1; GTF3A; ZNF410; LYL1; ZFP36L2; TSC22D3; LPIN2; RCOR3; HMG20A; ZNF34; BHLHE41; ZBTB20; SPIB; TAF1D; TRIM22; PPARGC1A; BCL6; HMGN3; THAP10; FOS; TLE4; GABPB1; SAP30; XBP1; RUVBL2; YBX1; RORA; FOXO4; TCF7; MMS19; HLTF; TWIST1; RBPJ; ADRB2; TAF12; SMAD1; PIAS3; CEBPG; NCOA1; KLF2; TSC22D1; BPTF; ERF; ZNF589; MED24; EZH2; TFDP2; UBP1; MED4; ZNF652; PATZ1; SNAI2; BASP1; BTG1; HOXA5; CRYM; ORC2; ZNF7; ID1; SMARCA1; RFX5; IRF2; AGO2; ERBB4; MNDA; FOXJ3; JUND; NR1D2; NLK; PSIP1; MED1; RBBP4; SSBP2; WWTR1; DLX2; HIPK3; PITX1; MAFB; REL; TRPS1; STAT5A; FHL2; STAT3; MYB; NKX2-1; TLE1; TULP4; CEBPA; DEK; ABL1; ID4; MSX1; CREG1; FOXG1; LEF1; ID3; ATF5; ELF5; HES1; EMX2
Down-regulation	188	CRK; TGIF2; PBX1; NFE2L2; OSR2; FOXF2; CCNH; ALX3; TGFB1I1; HBP1; ZNF432; ZNF140; MEIS2; SHOX2; SUMO1; HOXB6; FOXE1; NEUROD6; BNC2; HOXD3; ZBED2; BANP; ZNF667; COPS2; TBX10; ZEB1; E2F8; ZNF669; POU3F2; ARL2BP; ARID5B; PAXBP1; NCOA6; NRIP1; KDM5C; MED20; FOSL2; TCEA2; PBX2; IRX4; HTATIP2; HOXB5; CDK9; SAFB; ZNF84; HLX; SRF; VGLL1; NR4A1; PLAGL2; SUB1; DDIT3; PRDM4; E2F6; JUP; SOX15; ARID3B; ZNF268; CCDC59; HOXD1; TFAP2A; BARX1; PRDM1; BNC1; ZNF692; SUZ12; TRIM24; NR4A3; GFI1B; LHX1; ZNF133; MYCL; ZNF124; THAP4; HDAC9; ZBED1; ZZZ3; SMARCA5; ZNF134; SP3; MNT; SUPT4H1; STAT5B; BCL3; TCF7L2; CDC5L; DNAJC1; SMARCD1; HIRA; HOXB13; TAF1; BAZ2B; NFKB1; ZNF629; CEBPD; RB1; PAX6; ZNF586; UBE2B; ZNF671; ZNF337; MED17; NOC2L; HIC2; ATF1; LDB1; ARID5A; WNT4; ATF3; MEIS1; HHEX; ZNF217; IRF7; ZMIZ1; IFI16; HOXD11; SOX2; SPEN; BACH1; CHD9; ZNF606; ZNF334; WT1; MECOM; ADNP2; HMGXB4; HOXB2; SCAND1; AEBP1; HMGA2; NAB1; NFYB; PBXIP1; KLF13; SMARCD3; ID2; TCF15; RAD21; ZNF350; NR2F2; IRF8; PLAG1; NANOG; CHD1; FOXF1; PEG3; ZKSCAN1; CREB3L2; CBFA2T2; RBPMS; ISL1; TBX3; ZNF211; RBFOX2; CTBP2; MEF2C; CITED2; PHOX2B; HMGB3; NFATC3; SMAD3; TBX2; CERS4; ZSCAN18; TULP3; IRF9; LOXL2; ARID4B; ZFPM2; PHF20; TCF21; SOX17; NR1H2; NR2F1; KDM5A; INSR; SMARCA4; MYRF; VPS72; ZNF232; DMTF1; TBL1X; NR4A2; KDM5B; KAT6B; KLF6; GATA3; THAP11