Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69075	Cinnarizine	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	151	MTA1; HEY2; NFE2L1; NFIB; TGFB1; POU2F2; ZNF281; SOX4; HNRNPD; TFAP2B; MAGED1; HMGN3; ERBB4; BBX; ING2; SMAD1; KMT5A; ZFHX3; MXD4; ZNF443; DLX5; TSC22D4; DMTF1; CTNNB1; SP3; NFYC; PPARGC1A; PRDM2; CTBP2; PIAS3; SF1; GATA3; CREB5; SND1; ZFHX4; IRF5; KLF6; MYT1L; LMCD1; MEF2A; EVX1; PAWR; FOXJ1; GTF3A; MTA2; TRRAP; CARM1; AFF1; SOX9; ZNF711; NPAS2; ZFP36L2; KDM5B; HLF; ATF4; PHOX2A; FOXC1; CCNE1; ZKSCAN7; KLF2; BRIP1; PBX2; SSBP3; TFAP2C; SAP30; SHOX; BATF; ZNF512B; SCAND1; DDX54; PRRX1; PA2G4; NPAT; MEF2C; WWC1; HMGA1; GFI1; GLI2; ELF4; THAP7; ZMYM2; CNOT3; ZFPM2; SMARCC2; EP300; RBM39; DEAF1; KLF4; DNAJC2; DLX2; CALR; OVOL2; TSC22D2; DLX4; MEOX2; SLC2A4RG; HOXB7; SFPQ; JUNB; ZEB2; HOXB6; ZBTB16; ESRRG; SSX1; NFATC1; TEAD1; RUNX3; MYBL2; ZBTB20; NLK; GATA2; MAFB; POLR2A; ELF3; NCOA3; BHLHE41; ATF7IP; IKBKAP; SMARCA2; ZSCAN31; ERBB2; JUND; CENPB; FOSB; NFATC3; NKX3-1; CRYM; NCOA1; TULP3; DRAP1; KLF13; HOXB2; RORA; RUNX1; FLNA; FOXG1; CEBPA; TBL1X; IRF4; ENO1; KDM5A; FOXM1; AEBP1; THAP11; KAT6B; EGR3; EMX2; PBX3; POU2AF1; ESR1; TRIB3
Down-regulation	148	NR2F6; CCNT1; BRD7; CITED1; ZNF710; CDX2; RCOR1; ACTL6A; ZNF672; UBE3A; GTF2IRD1; LEF1; HOXA11; SUPT3H; SATB2; BAZ1A; TDP2; SNAI2; ZNF143; MED14; ZNF516; HMGB3; ZNF12; SREBF1; RFXANK; ZNF184; PEG3; PGR; E2F8; ETS1; CDX1; TTF2; PLAG1; CERS6; ZNF217; CHD3; TOX3; ZFX; TGS1; COPS5; IRF1; HOXA10; RELB; HMG20A; BCOR; TDRD3; EED; ZNF432; POLR3C; ZNF813; RNF10; HOXD9; CUX2; SUZ12; ZNF274; CD3D; FOXA1; MYCBP; TFDP1; INSM1; BCL6; ZNF10; RUVBL2; HOXD11; ZNF165; GCFC2; BASP1; BCL3; IKZF1; TRIP6; TAF9; CHD7; NEUROD1; RHOA; ELK4; HIVEP1; RRN3; ATF2; TCF21; YBX2; CDK8; BRF2; NR2C1; MAFF; PSPC1; NFYA; SAP18; ZNF189; WNT4; STAT6; PNRC1; CBFB; HIRA; RCOR3; BPTF; FOXJ3; PURA; YEATS4; KDM5D; BACH2; REL; GATA6; ID1; TGFB1I1; NR1H2; ZNF587; ZNF589; ORC2; MECOM; ARID4B; ZNF473; ATF3; KAT6A; MED21; ZNF337; IRF6; UBE2L3; ZNF586; TAF1D; SALL1; MYBL1; STAT4; LITAF; TCEB2; ZHX2; ZNF544; ETS2; MYCN; BTG1; ID2; NFE2L3; RBL2; NKX2-2; MITF; TOB1; ZNF468; CEBPD; MKL2; EHF; SATB1; HLTF; MYB; RFX5; ZIC1; DACH1; HOXA5; WWTR1; ZNF91