Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69021	Chlorthalidone	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	142	HDAC6; BBX; KDM5D; NFIB; PDLIM1; BCL3; SOX5; MYC; PITX1; MAGED1; PBRM1; BAZ1B; PHF2; JARID2; PRKDC; ZNF248; EED; MYCBP; CREB5; TFAM; HMGN3; APEX1; TMF1; TBP; CCNC; NCOA4; MEF2C; BMI1; TRIM32; SREBF1; NPM1; FOXO3; CRY1; EYA2; NUP62; NR1D2; NR1H3; BCL6; TCF12; NAB1; TOX3; ZNF23; PHF8; SMARCA2; HDAC4; SIX1; FOXO4; KLF10; CCNA2; RBBP7; MED6; GABPB1; ZMYM2; DEK; ZNF574; RYBP; IRF1; ELK3; MED21; EZH2; RORA; HMGB1; EYA1; HIVEP1; EDF1; AR; YBX1; ZNF432; TBL1XR1; POU4F1; TCF4; JUN; ZEB2; ZNF267; ATF1; ZNF721; PIAS3; HSF2; ZBTB20; NFAT5; KLF2; HLF; ETV5; HIPK3; USP22; ERG; HDAC7; PSPC1; AHR; TBPL1; RBBP4; SNAI2; MITF; BASP1; TRIM16; KLF9; CALR; CARHSP1; XBP1; POLR2A; ZNF593; LEF1; SIM2; ORC2; CUX1; ZBTB38; GATAD2A; NRBF2; MED1; PATZ1; PLAGL1; ESR1; ST18; ARNTL2; CEBPB; SMARCA1; MAFF; MEOX2; ZNF160; MEOX1; MED24; HLTF; SOX10; AGO2; LOXL2; TSC22D1; TWIST1; MAFB; RUNX1; NKX3-1; PSIP1; ZMIZ1; CHD9; EMX2; ZNF652; ID2; EGR3; TBX2; TLE1; WT1; KAT6B; HES1
Down-regulation	110	VDR; PBX3; ZNF557; SUZ12; CDK9; KDM5C; DLX4; GFI1; E4F1; HHEX; FOXL2; ZNF654; CDK2; FOXF2; OSR2; HOXB6; HOXA11; ID4; PSMC3IP; GLI2; FOXN3; EMX1; SUPT6H; ZNF79; CREB3; TFDP1; DLX2; TGIF2; ZNF200; BCL11A; DBP; ZNF215; NAB2; ZSCAN18; ZNF217; SOX9; NR2F1; TCEA2; FOXF1; GATA6; MEN1; NFX1; SP3; ZNF528; CBFA2T3; PBX1; SOX3; IRF6; SOX2; TCF21; PSMC3; PITX2; MED17; CDX1; HOXB13; FOXE1; SATB2; XRCC6; SOX13; PIAS1; ZNF552; ETS1; ZNF232; ZNF589; SSBP3; CDIP1; RUNX3; NKX2-1; ZBED2; POU2AF1; MYBL1; HMGB2; NFIC; HMGA2; RB1; RAD21; SMAD3; ZNF586; FOXM1; NPAT; ZNF131; SPEN; CERS4; KLF13; NFATC1; ZNF211; NFE2L3; WNT4; KLF4; STAT1; SHOX2; FOS; AEBP1; CTBP2; SOX11; PRRX2; IRF4; FOXC1; ZNF331; IRF7; SMAD1; INSR; TBL1X; NFATC3; TBX3; MYB; TOB1; CITED2; ZBTB18; KDM5A