Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69009	Scopolamine	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	188	CEBPZ; HOXB6; RUVBL2; TXNIP; E2F8; HOXB5; SOX4; MYB; HMGB1; MAGED1; ONECUT2; CIITA; ZNF282; KAT5; PRPF6; HMBOX1; EYA1; NACA; ZNF408; HDAC6; ZNF443; DMRT1; FOXD1; FOXC1; DPF2; CREB1; PTTG1; CENPF; KMT2D; IRF5; VGLL1; BLZF1; POU4F1; NR2F2; RUNX1; PAX6; MYT1; SIX1; WHSC1; HOXC4; HR; ZFHX4; DNAJC2; E2F6; KLF5; ENO1; ZNF248; TLX3; MED12; KLF7; TTF2; PURA; ARID3A; ZFP36L2; BRCA1; PCGF1; ZNF711; SERTAD2; ZNF574; MBD4; PRDM2; EZH1; ZKSCAN1; MZF1; HOXB7; MYCN; KLF10; ZNF692; ZNF274; ZNF222; E2F5; GFI1; MXD4; GATA3; DNAJC1; ZHX3; BMI1; E2F2; ERBB4; PITX2; ZNF33B; MDM2; ZNF205; NR3C1; HOXA1; GTF2I; TBX2; CTNNB1; ZBTB40; EGR4; PGR; BLM; NFE2L1; BARX2; TFDP2; ZNF444; NEUROD1; EYA2; HDGF; NPAS2; AATF; ZEB2; ISL1; NKX2-1; ESRRG; PAX5; POU2F2; SOX3; ING1; SSX1; HAND1; HMG20B; TRPS1; HDAC9; BCLAF1; CCNE1; SIRT7; ZIC1; FOXO3; HDAC4; NCOA1; SMAD7; ZNF267; ZMYND8; HDAC1; MECOM; JUP; ZNF22; DLX2; RRN3; SIAH2; PIAS1; MEOX2; MBD2; PHOX2B; ING3; CHD4; TAF7; TSC22D3; TFAP2C; DMTF1; ZNF394; JUN; IRF6; PLAGL1; KLF2; HMGN3; MLLT10; LYL1; TP53; SMAD1; MLXIP; MSX1; ELF3; ATF7IP; BTG1; SHOX2; HMGB3; NFIC; KLF6; ATF1; ETS2; ZNF544; RBBP4; MED6; ZNF587; KDM5D; CTBP2; ERG; CREG1; YBX1; HIC2; EGR3; MEOX1; ZNF160; ASCL1; ARNTL2; BHLHE41; NFIL3; KAT6B; KDM5B; BAZ2B; TOX; DRAP1; CEBPA; TLE1; ATF3; ZBTB18
Down-regulation	212	MYC; GTF2A2; C1QBP; CDK9; RNF111; BRD3; YAP1; RCOR1; LIN28A; PEG3; PTRF; TGIF1; TGFB1I1; ZNF467; NANOG; RREB1; BRD7; NFIB; MED14; WWP1; PRKDC; DR1; TAF11; ZBTB43; REST; WDR77; NFKBIA; ELK4; IKBKAP; NELFB; TLE2; NFYC; TTF1; NRL; MNDA; NRIP1; HSF1; SATB2; TCF20; HIVEP1; BNC2; SMARCD2; CRY1; MEIS1; ZHX2; PRDM10; DEAF1; GATA6; MAF; ZNF32; SMAD4; SP2; STAT6; TGFB1; IRF8; ZFPM2; ZNF573; NFRKB; BIRC2; ADNP2; ABL1; FOXO1; FOXN3; CAMTA2; YEATS4; DAXX; ZNF140; MYRF; ZNF76; ELK3; CEBPD; FOXJ3; YAF2; HMGB2; LOXL2; HIPK1; TGIF2; SMARCD3; CREB3; TRIM22; NFATC1; SREBF1; KAT2A; HOXA4; URI1; HOXD11; KLF9; RBFOX2; ZBTB14; CBX5; IFI16; ZEB1; CD3D; ZNF131; AGO2; CERS4; PKNOX2; TRIM33; NR5A2; STAT1; TCF12; CDC5L; CREM; SUPT3H; ZFP36L1; SREBF2; ZNF135; ID2; FUBP1; MGA; NKX2-2; KLF11; JARID2; ZNF329; MXD3; RLF; ARID5B; WIZ; PBX1; TBX3; ZNF189; ZNF423; HMGXB4; THAP10; SALL2; FOXL2; PHF1; ZNF532; NFKB1; NR0B1; ZMIZ1; ETV4; ENY2; NFX1; BTAF1; SMAD3; FOXK2; HOXB13; CHD1; NR1H2; ANKRD1; NCOA2; CITED2; BASP1; FLNA; WWTR1; IRF3; CEBPB; HHEX; PSIP1; MTDH; ZNF124; NFKB2; EHF; ZSCAN31; BCOR; THAP11; ZNF239; MEIS2; ZNF83; TBL1XR1; YWHAB; MAFF; GATAD2A; NKX3-1; ZNF7; FOSL1; RERE; REL; SOX17; BATF3; SATB1; SALL1; CITED1; RBM14; MEF2C; SFPQ; SIN3B; MED15; ZBTB38; BRD4; ZBTB20; ID3; ZBTB1; ZNF580; SUB1; SSBP2; GATA2; ZNF217; SOX11; ERBB2; STAT4; AFF1; PHF20; ARID4B; WNT4; MKL2; ZMYM2; CHD7; HOXA5; EMX2; HES1; RFX5; ZNF91; ZSCAN18; PCGF2; FOXM1; WT1; FOXF1; ZNF512B; TAL1; KDM5A