Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68983	Mdm2-inhibitor	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	TP53; NFKBIA; ABL1; RUVBL1; POU2F2; RHOA; TRIM28; SAFB; MTA1; FOXL2; TLX1; ZNF787; HMG20B; SCAND1; PKNOX2; NFIX; GMEB2; RFXANK; ZNF205; SREBF2; SMARCD2; AIP; PARP1; FOS; MAFF; TCF4; ZNF282; RUVBL2; TCEB2; ZNF711; MEF2D; LHX6; NANOG; HEY2; KMT2B; KAT6B; GATAD2A; ZNF8; EZH2; SLC2A4RG; BNC2; SATB2; ZNF671; PCBD1; KLF6; FOXO3; ALX1; INSM1; JUND; SMARCA2; BTG1; NOC2L; FOXF1; BRF2; MAFB; PITX1; POLR2A; SOX2; SIAH2; SMARCA1; E4F1; USF2; CERS4; PAX6; ZIC1; MMS19; ZNF500; SOX9; ARID4B; ETV5; PNRC1; UBE2I; ZNF593; SOX17; TFEC; HIRA; ZNF580; CARHSP1; DNAJC1; TXNIP; HSF2; C1QBP; MED24; TCEA2; EDF1; TBPL1; HEY1; TOX3; NFIL3; NFATC1; MYCN; FOXG1; MAF; ATF5; ID1; SOX13; MSX1
Down-regulation	169	DMTF1; CDK7; PSMD9; FHL2; ZMYM2; EGR2; RNF138; PMS1; ZKSCAN1; TLE1; BRCA1; ZNF12; CHD9; TCF7; SMARCA5; GTF3A; ESRRA; TRIM22; FUBP1; IRF7; SP100; LEF1; MTDH; TSC22D3; HOXB2; ZNF195; NR2C1; RUNX1; DNAJC2; ZNF354A; ZNF44; BAZ1A; MGA; NFIB; ZNF7; MYC; KAT6A; RELA; SAP30; HDAC6; CREB3; UBE2B; STAT6; IKBKAP; RBBP8; MED7; DEK; ING2; ZNF273; SIX1; NFYB; TRIP11; CHD1; RAN; ZBTB11; HOXD1; TRIM29; USP22; TSG101; ECD; PAWR; TAF1D; ZNF107; NFE2L1; NRBF2; PHF20; BBX; ZNF232; STAT3; FOXN3; TAF9; SMAD3; ZNF33B; KDM4A; CCDC59; MEIS1; SNW1; NCOR2; RNF6; PATZ1; SP140L; RREB1; CREBZF; NUP62; HIPK1; ZZZ3; RNF111; EHF; PSPC1; HMGN3; NAB1; ZNF443; DDIT3; ZBED1; KLF3; ZFP36L2; BAZ2B; HOXC6; ITGB3BP; CREB1; ATF3; NR1H3; EED; ZNF140; ELF4; SERTAD2; EGR3; ZNF623; HOXB6; ZNF721; RYBP; NFYC; NFYA; C1D; AGO2; HMGB2; SOX4; ZNF652; VEZF1; KLF10; MBD2; ZNF131; AEBP1; SMAD2; TERF2; ZNF160; PBX1; BASP1; ZNF587; BTAF1; TBX3; BCL10; ASCL1; ZBTB1; HMGA2; PLAGL1; ERBB4; RORA; ARNT2; ZNF665; CCNH; REST; TGFB1; ZFPM2; CITED2; MEF2A; FOXJ3; VDR; ZNF189; MAGED1; ELF5; HTATIP2; ZBED2; TOB1; ID3; MYBL1; CTR9; ZSCAN18; SMAD1; BHLHE41; SFPQ; TCEA1; ZNF117; ERBB2; PHIP; NKX3-1; TRIB3; MYB; IFI16