Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68976	Dibenzepin	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	NKX2-1; KLF6; TOX4; ETS1; TCF21; PBX2; TBX21; SLC2A4RG; HIRA; ZNF688; NFATC3; GATA1; CITED2; COPS5; SOX21; FLI1; ZNF768; BARX1; NOC2L; FOXK2; MNDA; LHX3; CSDC2; NFE2; CEBPE; PRDM14; ZNF444; E2F4; KLF7; ZNF215; PRDM10; BNC2; MXI1; SIX3; ZNF611; ZNF544; ZNF671; SSBP3; NR4A2; TSHZ2; RLF; CALR; TRPS1; JUND; HLX; AEBP1; E4F1; WNT4; AR; ZFPM2; PSMC3; GFI1; NCOA2; HEY2; POU2AF1; ZHX2; JUN; LMCD1; ESR1; CAMTA1; CDIP1; FOSB; CREB3L2; MYBL1; ZBTB16; CEBPD; KLF1; WT1; NR1H4; PEG3; ID4; NFE2L3; TFAP2A; SPDEF; REL; CEBPB; ZNF117; HMGB3; IRF6; STAT4; MEIS2; ATF5; ZNF331; INSR; TCEA2; ID1; TRIB3; IFI16; DACH1; MYB; NFIL3
Down-regulation	213	HMG20B; IKBKAP; DMTF1; USP22; ZKSCAN1; NUP62; SSBP2; MAML1; ZMYM2; ZNF12; PMS1; BRCA1; EED; SMARCA5; SAP30; ITGB3BP; TSC22D3; PHF20; CRK; SPEN; OLIG2; ZZZ3; PATZ1; CLOCK; TLE1; ZKSCAN5; DEK; PKNOX1; CNOT1; TRIM29; NRBF2; ZNF443; CENPF; SMAD3; PSIP1; SP3; CHD9; RNF6; ZNF430; HDAC6; BASP1; MED7; CENPB; MGA; NCOR2; BBX; ZBTB11; RNF4; XBP1; E2F3; ING2; UBE2B; MYC; NCOA4; SAFB2; HLF; ZNF267; ZBTB38; PBRM1; NAB1; YBX1; PITX2; MITF; CHD1; SMARCD3; ZNF302; THAP1; MED23; PAXBP1; ZFX; ZBED1; KAT7; NR2C1; ZNF473; DNAJC2; STAT6; TRIP6; TRIM28; FOXJ3; CCNC; CDK8; RBBP5; SETD2; ATF1; ZBTB18; BCL10; TRRAP; SMARCA4; REPIN1; CREB3; GTF2IRD1; COPS2; PLAGL2; MED6; HIPK1; MAGED1; ZBED4; BRIP1; TAF6; ZNF337; ZBTB1; MTF2; TCF12; CDK2; TFAM; TOPORS; HES1; ZBTB24; SUV39H1; ZNF131; NFAT5; CARM1; ZNF3; PQBP1; ZNF184; NFYB; EGR3; RNF138; LEF1; VEZF1; TMF1; ELF2; BAZ1B; TSC22D4; LIMD1; REST; ELK1; STAT1; CBX3; ZNF32; BPTF; BRPF1; DDX5; MEOX2; ETV1; C1D; TAF1D; PHF2; ZEB2; NR1D2; NR1H3; MLX; EGR2; NPAS2; ZNF124; NKX3-1; ZNF529; TRIM16; PSPC1; CDYL; ZNF14; ZNF22; ZNF148; ZNF189; ZIC1; BATF3; GMNN; TOX3; UBP1; SATB1; BMI1; ERBB2; ECD; ID3; PIR; PHF8; ETS2; IKZF5; SFPQ; ARID4A; TEAD1; MED1; TAF10; WWC1; BRWD1; ZNF24; SMARCE1; ELK3; HMGA2; DLX2; JARID2; BRD8; ING3; USF2; SMAD2; BLM; CRY1; SMAD1; BCLAF1; BIRC2; FLNA; SMAD6; MAFB; TSC22D2; TBX3; ZMIZ2; ID2; HIC2; HMGB2; TOB1; MED13; MEF2A; TBL1X; MEIS1; HLTF; ASCL1; AHR; ZNF134; SOX9; CTBP2; HOXD1; CTR9; ZNF586