Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68968	Irsogladine	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	82	TP53; CEBPZ; MAFF; NFKBIA; RUVBL1; NRIP1; SAFB; FOXL2; SIRT7; MYBL2; KLF6; MTA1; RHOA; SCAND1; ABL1; JUND; KMT2B; PARP1; SMARCA1; KAT6B; MKL1; BCL6; INSM1; MSC; TCF21; HLF; NANOG; SLC2A4RG; BTG1; DDX17; TCF25; GATAD2A; MAF; BNC2; ZBTB38; MAFB; BANP; ALX1; TCEB2; CREM; CARHSP1; HSBP1; HEY2; LHX2; KLF9; NR2E1; HIRA; HIPK2; ZNF264; E2F2; STAT5B; SATB2; VGLL4; FOXG1; AEBP1; PTTG1; POLR2A; CEBPB; ID1; ZBTB20; PITX1; ID4; SREBF1; UBE2I; ATF5; PBX3; NR1H4; NFIL3; CALR; SALL1; STAT5A; MEIS2; TWIST1; KLF2; TBPL1; SOX9; ZNF331; IRF6; ZIC1; NR2F2; TCEA2; GATA6
Down-regulation	144	DMTF1; IKBKAP; ING2; UBE2B; ZNF354A; TRIM29; TCF7; ESRRA; BRCA1; LEF1; TRIM22; ZNF12; CHD9; SIX1; KAT6A; PSMD9; NR2C1; ZNF131; NCOR2; E2F8; ZNF7; SOX4; FOXN3; SAP30; AES; MGA; NFYB; ZNF107; PLAGL2; NFE2L1; ZKSCAN1; ZNF16; CHD1; ZNF273; RNF10; ECD; MED7; MED12; TFCP2L1; KLF10; SMAD1; ZNF268; SMARCD3; ZNF33B; FUBP1; RNF138; RNF6; CD3D; DNAJC2; BASP1; SMAD3; ZBTB11; STAT3; PATZ1; MEOX1; MTDH; GTF3A; MEN1; ZFHX3; HIPK1; ZMYM2; ITGB3BP; CREB3; ZNF443; RAN; TSG101; RUNX1; XBP1; NPAS2; CCDC59; HOXD1; DEK; ZNF124; SNW1; ZBTB18; RBBP8; ZNF217; NCOA2; KLF5; HDAC6; TLE4; HOXC6; EGR2; ZSCAN31; RUNX3; NKX3-1; TLE2; REST; ZZZ3; ZNF32; ZBTB1; FOXE1; RNF111; BRIP1; TBX3; MED6; AFF1; CRK; ZNF467; ZNF232; CALCOCO1; ELF4; ZNF329; TAL1; NUP62; STAT1; ERBB4; BAZ1A; ZNF623; ZFP36L2; PHIP; KLF3; TGFB1; ZNF652; ZBED1; MDM2; NFIC; HOXC10; NR1H3; TERF2; EGR3; ZNF587; VEZF1; BRD8; ZNF415; MAGED1; HMGB2; CTR9; TOB1; HMGN3; ZSCAN18; SMAD2; ZNF304; YWHAB; ZNF419; ZBED2; ID2; ERBB2; VDR; MEIS1; TCEA1; INSR; CRY1; SFPQ