Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68951	Ponalrestat	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	TLX1; CD3D; POU2F2; TBX21; PKNOX2; CEBPE; NFIX; OVOL1; ETS1; CDX1; LHX3; INSM1; PAX1; FOXF1; GRIP1; ZNF688; ATOH1; TCF21; PBXIP1; SIRT7; HSF4; E4F1; TONSL; PEX14; SOX21; PEG3; HOXB1; CDIP1; TCEB2; NPAS1; NEUROD1; NR0B1; ZHX2; NR4A2; AR; JUP; CBX4; ZNF205; CARHSP1; NANOG; NOC2L; DDX17; CSDC2; NFKBIB; PRDM14; MSC; SIX3; NFATC3; JUND; SPIB; EN1; E2F4; ZNF671; PIAS4; VGLL1; SOX13; DBP; BNC2; ZNF345; RBPMS; BARX1; ESR1; MXI1; NR5A2; ID4; PRDM12; NKX2-1; YAP1; SUPT3H; ZNF93; OSR2; NR1H2; SMARCA1; ZNF331; HLX; WT1; PGR; KLF9; HDGF; GFI1; TP73; SSBP3; PCGF3; BCL11B; JUN; ZNF253; TDP2; PAX6; KDM5C; CEBPD; FOXF2; CERS4; TRPS1; BTG1; LMCD1; STAT4; CEBPB; LIN28A; NR1H4; ZNF589; AEBP1; TFAP2A; ZFPM2; ZBTB20; TULP3; SATB2; UBE2I; IRF6; SPDEF; MEIS2; POU2AF1; TOX; GATA6; DACH1; TRIB3; FOXG1; ZIC1; ST18; ZNF91; NFIL3; MSX1
Down-regulation	247	ZMIZ1; DMTF1; IKBKAP; PHF20; COPS2; ZMYM2; USP22; NUP62; ZKSCAN1; UBE2B; BRCA1; TRIM22; MAML1; SAP30; ZNF12; CRK; SP3; NCOR2; PMS1; YEATS2; PSMD9; PSIP1; NFYB; RBBP8; NRBF2; CENPF; ZNF44; HDAC6; PLAGL2; EED; ING2; TLE1; MGA; ZNF45; SMARCA5; ELF2; BAZ1A; PATZ1; CHD9; ZNF410; ZNF430; SMAD3; DEK; TOPORS; ZBTB18; TADA3; XBP1; RNF111; TCF12; DNAJC2; MED6; ZZZ3; CNOT1; BAZ1B; ZNF672; ZNF468; SUV39H1; ZNF629; CHD1; RNF6; CBX3; ADNP; TFCP2L1; ZNF3; ZBTB11; ECD; DR1; TRIM29; PKNOX1; RNF138; ATF2; NEDD8; KAT6A; LEF1; HDAC7; BASP1; NKRF; STAT1; CREB3; STAT6; MED23; NAB1; NFIB; SNW1; ATF7IP; FOXJ3; TCF4; MYC; KLF10; CBX5; THAP10; ZNF107; TAF7; BPTF; MTF2; ZBTB1; PCBD1; TRIM24; TOB1; RUNX1; E2F8; KMT2A; NR2C1; ZNF266; NFE2L1; C1D; ZNF443; BRD8; ZNF226; KAT7; GTF2IRD1; MITF; KAT6B; CCNA2; NCOA6; MECOM; REPIN1; ZBED1; THAP1; SETD2; VEZF1; TBL1XR1; DAXX; PQBP1; SIX1; HMGA2; UIMC1; CENPB; HOXB6; MED7; SMAD4; ITGB3BP; RAN; OLIG2; FUBP1; RNF10; WWC1; SMAD5; ZFP64; ZNF189; BCL10; NPM1; ATF1; ZNF84; MEIS1; BRIP1; UBP1; BCLAF1; ZNF131; HIPK1; ZNF217; E2F3; ZNF267; RFX7; SF1; TRRAP; SMARCE1; EGR2; ORC2; ETV1; NFAT5; HMGN3; TCEA2; NPAT; HOXC6; TAF1A; TLE4; ARID4B; MED13; HMG20A; ASXL1; ZNF184; ZEB2; RB1; WWP1; RBBP7; ZNF652; RCOR3; TERF2; PHF2; AFF1; ISL1; TRIM33; BBX; KLF5; ZNF148; STAT3; SFPQ; REST; PSPC1; CUX1; ETS2; SAP18; TRIM32; ARID1A; BMI1; SATB1; ERBB2; BRPF1; ZNF587; RBBP4; ARID4A; BIRC2; STAT5B; BATF3; RNF14; GMNN; HMGB2; BAZ2B; MAGED1; SMAD2; HNRNPD; ZBTB38; NKX3-1; NR2F2; ZNF329; ZNF14; BACH1; CBFB; ELK3; ZNF512B; ZNF134; ZMIZ2; PIR; CTR9; ID2; LPIN2; ID3; MEF2A; ID1; AHR; SMAD1; SALL1; NR1D2; DDX5; MYCBP; TSC22D1; ZSCAN18; TSC22D2; PIAS2; EGR3; HLTF; ING3; FLNA; MED1; MYBL1; KDM5D