Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68949	Sb-431542	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	385	NFKB2; KDM4C; DBP; PDLIM1; PPARD; IKZF1; TCF15; MYOG; BHLHE40; FOSL2; MNDA; HMG20B; CEBPA; CEBPZ; TFDP2; FOXO4; MYT1L; TXNIP; BANP; FOXE1; HLF; JUP; PAX8; FOXJ1; SMARCA2; ZNF175; STAT1; PRMT2; SPEN; PHF1; TGFB1I1; ZBTB38; SMARCD2; E2F8; DAXX; NFX1; HR; HIVEP2; MBD1; GCFC2; HDAC4; WNT4; LHX6; FHL2; NKRF; SNAI1; NPAS1; LIMD1; TCF4; GLI1; SIAH2; ZNF324B; LYL1; BATF; FOXL2; MNAT1; PML; TFEB; HMGXB3; RARG; ZBTB7B; MAX; EPAS1; HAND2; NKX6-1; MAFK; NKX2-8; HDAC7; ZBTB40; CASZ1; PDX1; KLF9; ZNF556; CREG1; XBP1; ING1; HOXC8; GFI1; MNX1; POU4F1; ZSCAN5A; TSC22D3; AIRE; ZNF276; TGIF1; EHMT1; NEUROD2; ZMIZ2; FOSB; FOXJ2; NEUROG1; TLE1; NR3C2; FOXN1; ZMIZ1; TOB1; TRIM25; LHX5; ZNF226; MEF2D; IKZF5; ZNF696; IL16; ZNF384; NFKBIB; RFX2; SSX3; TEAD3; ZKSCAN3; HIPK1; TBX21; MAFF; ZNF335; ZNF292; MAP3K10; HOXA6; GATA2; NFAT5; TRIM22; ARID4B; TULP1; HOXA5; OSR2; NOCT; HMX1; EN2; PRDM8; ERF; ERCC2; STAT3; ZNF580; MYRF; ZNF646; AFF1; ELK4; THAP3; HIC1; NFATC1; POLR3C; HES2; WT1; TRIM32; SP3; CRTC1; ZNF574; TSC22D4; NEUROD6; TONSL; BARX1; ZNF394; TAF1C; ESR1; MSC; NCOA1; CRX; EYA3; SERTAD2; HOXC11; CD3D; DR1; TDRD3; REL; HDAC11; HOXD9; SIX5; GLI2; KLF10; CAMTA2; TEF; HOXA1; DYRK1B; MYBL2; POU3F1; ELF1; CEBPE; THRA; IRX5; CBX4; BCL10; TAF6; BIRC2; PIAS3; PAX2; OVOL1; CDX2; HOXA10; TCF3; ZBTB48; LHX1; TRIP11; SMAD2; SREBF2; NPAT; PITX3; AGO2; JUNB; ZBTB25; ZNF506; SHOX2; NFE2L2; SUPT6H; HOXA3; KAT6B; MED25; EVX1; NRL; RBL2; HOXD3; POU6F1; IRF5; AES; CREB3L1; TRIM16; SP140; RBL1; WHSC1L1; SPDEF; TBX4; ARID4A; ZNF286A; GRHL2; ZZZ3; KMT5A; JAK2; ASH1L; ZNF446; SIRT7; GTF2I; UIMC1; MKL2; MTA1; USF2; KDM5A; RXRB; LMX1B; RREB1; NR1D2; RNF14; MTA2; MDM4; HOXA7; ZNF771; CIR1; PRDM14; ONECUT2; CDX1; NR4A3; SETDB1; PAX6; ZNF711; NFE2L3; TBX10; RUNX1; ZHX2; ZNF510; TEAD4; POU5F1B; USP16; ZHX3; ZNF205; CBFA2T3; SKI; KDM4A; ETV2; CSDC2; NR5A2; NFE2; MXD1; KDM5C; CIC; TRIM27; IRF8; FOXC1; PRDM1; EMX2; GATA4; PNRC1; BPTF; MZF1; HIF3A; HSF4; MED15; PHOX2A; SETD2; ZNF629; FOXI1; STAT5A; TFDP1; KAT7; ZNF536; BNC2; LPIN2; KLF1; HDGF; HOXC10; ELF3; PPARG; MYB; ATOH1; CDYL; ZSCAN31; TRIM24; ZNF267; VDR; HEY1; NR5A1; SHOX; RB1; ZNF23; SIN3B; ZNF189; MYF6; RFXANK; MLLT1; PBXIP1; PIAS2; SOX18; POU2AF1; PAXBP1; BCL11A; BHLHE41; DNAJC1; SMARCA1; NFE2L1; EHMT2; PURA; WWTR1; NFATC4; TLX3; BCL11B; KLF2; YEATS4; RNF111; TGIF2; HSBP1; HHEX; KAT2B; HOXD10; CIITA; TBL1XR1; USP21; BACH1; FUBP1; GABPA; ZNF444; BRD2; MYOD1; EP300; BRWD1; CHD1; MXD4; MDM2; FOXA2; CUX1; MEF2A; HOXA4; EMX1; ZNF253; ITGB3BP; HIPK3; STAT5B; LOXL2; HOXD1; IRF1; ZIC1; BATF3; AHR; POLR2A; CBX7; ATN1; IRF9; LEF1; HOXB7; FOXN3; TFEC; WWC1; BCLAF1; BACH2; BMI1; ZFP36L2; FOXO3; IRF6; HTATIP2; ST18; BASP1
Down-regulation	466	SOX11; PUF60; USP22; HIF1A; SMARCC1; EZH2; CCNC; APEX1; RAN; CBX5; E2F5; ZNF195; NFATC3; SUMO1; NONO; CHD8; SMARCC2; XRCC6; SOX2; ZNF232; ID4; DRAP1; CRK; SSRP1; ZBED4; ZNF44; SALL2; GMEB2; ABL1; PRKDC; ZNF268; ENY2; ZNF611; ZKSCAN1; TOX3; TSG101; JUND; HCFC1; HDAC2; ATF2; IKBKAP; ZNF721; EED; VGLL4; ILF2; THAP4; MEOX1; SOX4; HMGB1; ZNF667; TRIM28; BRD7; DMTF1; MED17; PQBP1; TCF20; NCOR1; INSM1; FOXA1; C1QBP; ZNF426; DNMT1; CCNA2; CARM1; CERS4; WDR77; BCOR; TAF11; PSMC3; PLAGL2; ZBED1; ZNF140; MED23; PFDN5; SCAND1; ZFP30; SF1; ARID1A; ZNF32; MDFI; ZNF334; ISL1; EGR2; BRD4; ZNF432; ADNP; FOXO1; THAP10; TAF9B; MEOX2; CREB5; AEBP1; ZNF160; CNOT6; ARID3B; ZNF136; ZNF529; RRN3; ATF4; MNT; PBX3; PRDM10; SOX3; HDAC1; ESRRA; ZNF131; TCF7L1; NPM1; ZNF177; TAF10; PRPF6; TCEB2; KAT6A; ZNF562; ZNF787; SUPT7L; TRIP6; RUVBL2; HES1; HOXB2; URI1; CHD7; ZIC3; E2F3; SP2; TFAM; UBTF; GTF2A2; PITX2; L3MBTL1; DDX17; ZNF302; CARHSP1; ZNF219; TCEA1; GTF3A; ZNF12; BRD8; ZNF688; TBP; SMARCE1; ZFHX4; SSBP2; ZNF84; TGS1; CENPF; ERCC3; HDAC3; RBM39; ZNF3; RERE; POLR3F; ENO1; ZMYM2; MBD4; KAT5; ZNF35; HEY2; CITED1; GMEB1; SIX2; ZNF212; ID3; SMAD1; HMGB3; TOX; NRBF2; GLI3; MYBBP1A; PROX1; YAP1; MKL1; PSMC3IP; FLNA; ZNF337; SRF; TAF1D; ZNF512B; CTBP2; ASCL1; COPS5; RBBP7; ABT1; CBFB; ZNF43; TULP3; DDX5; RBPJ; TP53; KMT2B; STAT6; MTDH; SUB1; ZNF222; ADNP2; ZNF142; HIC2; CUX2; FOS; ZNF135; C1D; ZNF180; PHF8; TCF7L2; MAFB; TRRAP; RCOR1; ARL2BP; MED31; HOXB5; ID1; RAD21; SAP18; KLF6; ZNF112; RYBP; E2F1; RBPMS; ZFP37; HMGN3; CNBP; CALR; ZMYND8; ZNF415; HMGB2; WWP1; CTBP1; SREBF1; HDAC9; CARF; MTF2; BLZF1; HIRA; ZNF816; ZNF665; BAZ1B; ZBTB7A; ZNF282; EN1; CBFA2T2; FOXG1; NKX3-2; SMARCB1; NR1I2; ZBTB39; ZNF83; HNRNPD; HAND1; ZFP69B; ZNF468; TAF1A; ZNF235; PARP1; TAF4; ZSCAN9; PPRC1; INSR; GATAD2A; ZNF33B; MSX1; ZNF573; ZNF551; LIN28A; CEBPG; RNF4; KLF7; NCOA3; MED21; GON4L; RING1; SLC2A4RG; CDK7; ZNF223; ARNT2; TCF7; NFYB; MED20; CDIP1; UBE2B; HDAC6; EYA1; PTTG1; ZNF146; NRIP1; SUPT3H; ZNF835; PMF1; NFIB; ZNF174; PLAGL1; PIAS4; NCOR2; FLI1; ZBTB20; KAT2A; SOX15; PCGF2; MAZ; SUZ12; ZNF606; ZNF224; ARID3A; RBBP5; SMARCA5; MED4; TLE4; SAP30; HSF1; DLX2; ZFP36L1; CHD9; ATF3; TCF21; RCOR3; TOX4; ZNF329; ZNF443; ZNF215; ZNF124; BTF3; ZNF669; ZNF91; MED7; KMT2A; CREB3L2; ZNF10; SIM2; ZSCAN18; TBPL1; MECP2; ZNF528; ARID5B; ATF5; ETV5; HMGA2; WIZ; HMGXB4; PATZ1; PBX1; ZNF155; MTF1; HIPK2; ESRRG; GFI1B; RNF138; SNAI2; POU3F2; ZKSCAN7; SOHLH2; FOXJ3; ZNF165; ZNF544; AIP; ZNF248; DDIT3; CERS6; CDK2; KAT8; ZNF362; CREB1; ZNF671; RNF6; NR2C1; ZNF593; ZBTB1; SETD3; ZNF675; CHD4; BAZ2A; ETS1; ZNF345; NFRKB; LITAF; KDM5D; TSC22D2; HOXB6; YWHAB; ZNF623; TAF7; NR1H2; JARID2; MMS19; PEX2; ZFP64; KLF13; NHLH2; ARRB1; IRF7; SP140L; ZNF419; HOXD11; HESX1; BAZ2B; ZNF254; BRF2; DACH1; RXRG; RBBP4; MBD2; MED14; TAF5; YBX1; MYCBP; ZNF589; SIX3; ETV1; TBX3; ZBED2; PCGF3; GTF2IRD1; NAB1; CITED2; CEBPD; ZNF587; CTCF; MEIS1; CBX3; KLF11; HSF2; RSF1; MED6; MITF; ZNF304; PHIP; HOXB13; RNF141; UBE2L3; YBX2; HLX; SMAD7; ORC2; TGFB1; PAWR; CTR9; TBL1X; MED1; DNAJC2; RXRA; ELF5; SFPQ; NR1H4; CRY1; TERF1; MED13; GABPB1; ZNF350; MECOM; TCEA2; CAPN15; HCFC2; GMNN; ZNF211; ZNF24; EYA2; SOX9; TFCP2; ZNF117; UBE2I; ID2; PIR; MEIS2; PEG3; NFIL3; ZNF586; NR2F2; TRIB3