Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68910	Alprostadil	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	147	TAF1C; TBX21; TAF5L; ZNF335; HOXA1; NR0B2; LHX3; ETS1; CDX1; ELK4; JUP; GBX1; ARL2BP; CBFA2T3; ZNF654; THRB; SP140L; MAFF; PHF1; CD3D; LZTR1; PBXIP1; SPI1; HSF4; CBX4; E4F1; NFKB2; NR1H2; ZNF239; E2F4; DAXX; VENTX; CNOT3; NR4A2; FOS; NFE2L2; ATOH1; JUND; ZNF331; LHX6; NFATC3; PAX5; KDM5C; HIRA; ZSCAN9; BARX1; TGFB1; NR5A2; FOXF2; KLF7; WNT4; SIN3B; PRDM14; PRDM1; IL16; LDB1; PRDM2; RAD21; IRF6; KLF6; EP300; NR4A3; TP63; NANOG; BNC2; SLC2A4RG; HHEX; ZHX2; TCF21; PRDM12; SP140; NR1H4; NR3C2; RORC; GATA1; PIAS4; SUPT3H; SOX13; POLR3C; HLX; HDAC9; SNAI2; SPDEF; FOXE1; KDM4C; CCNT1; TFAP2A; ZBTB20; CSDC2; CDIP1; IRF9; TXNIP; FOSL2; MLXIP; ARNTL; CDK9; NOC2L; CREBL2; ZNF580; ZNF544; CEBPD; JUN; THRA; THAP7; ESR1; ZNF350; CREM; STAT4; SOX10; CERS4; RXRA; TEAD3; NFATC4; SATB2; EMX1; ZNF500; TP73; KLF9; ATN1; ZFP36L1; NFE2L3; MYBL1; ZNF117; CBX7; CCNH; IFI16; CALR; IRF8; BHLHE41; TRPS1; CEBPB; PEG3; HEY1; GATA6; DACH1; WT1; MEIS2; KLF11; UBE2I; VDR; NR4A1; HOXA5; TRIB3; POU2AF1; TFAP2C; ZNF91; NFIL3
Down-regulation	251	CRK; IKBKAP; ZMYM2; SOX11; PATZ1; SPEN; ZKSCAN1; NCOR2; MYC; NUP62; SAP30; BASP1; TCF12; SMARCA5; COPS2; VGLL4; DRAP1; NEDD8; SOX4; SUV39H1; E2F5; GTF3A; BRCA1; NR2C1; RUNX1; FHL2; CCNA2; BRCA2; HDAC6; BRD8; BAZ1A; BCOR; SIX1; KMT2A; EZH2; KAT6A; PUF60; PHF20; TAF1D; NAB1; EED; PMS1; ZNF248; MAGED1; TSG101; COPS5; MGA; ING2; TLE1; ZNF292; SMAD3; USP22; DPF2; NCOA6; BAZ2B; PSIP1; WDHD1; RELA; RCOR1; SMARCE1; SCMH1; CCNC; ZNF131; TBP; TRIP6; TCF4; LEF1; TRIM24; ZNF302; ZNF430; FOXD1; ARNT; KAT8; RSF1; MEN1; CNOT2; ATF2; PBX1; PSPC1; NRBF2; CARM1; CNOT1; E2F8; CERS6; NFE2L1; BMI1; BIRC2; RNF6; TAF9B; SMARCA4; ZBTB11; PBRM1; ZNF629; HDAC2; SETD3; MED6; PQBP1; SNW1; RLF; RBM14; ZBTB18; BAZ1B; YAP1; ENO1; ZNF146; ATF4; RAN; UBE2B; ZFP36L2; RBBP4; ERBB2; ZNF672; PHF8; RNF4; SF1; PLAGL2; TAF10; DEK; KLF5; PAXBP1; CLOCK; RNF111; TRIM29; TCEA2; GTF2IRD1; CDK8; ZNF107; FOXJ3; MSX1; MYCBP; ATF7IP; HMG20A; ZEB2; PSMC3IP; CREG1; MLX; HIVEP1; PIAS3; NKX3-1; EBF2; DNAJC2; MTDH; NFYB; NPAT; TRRAP; ZMYND11; CHD7; RBBP5; CTR9; E2F3; ETV1; RBBP7; ZNF12; NCOA4; ZNF529; TBL1XR1; ETS2; ZNF443; BCLAF1; MEOX2; ZNF22; HNRNPD; NRIP1; BTAF1; ZNF652; MED1; ZFHX4; BRIP1; GABPB1; RNF141; REPIN1; REST; NR1I2; ZBTB1; RREB1; RFX7; TCERG1; CITED1; ZBED1; YBX1; ZNF267; ARID4A; NR2F2; ADNP; ASCL1; DNAJC1; SETD2; SAP18; VEZF1; NFIB; ZNF184; WWC1; MEIS1; APEX1; ZFP64; HMGN3; NFYC; BCL10; EDF1; CHD9; ELK1; PCGF2; BLM; KDM5D; TSC22D1; AFF1; MECOM; EMX2; TEAD1; CHD1; CREB1; HOXC6; ING1; RNF10; HCFC2; ID3; DDX5; TOB1; TSC22D2; HOXB6; USF2; ARID4B; TRIM16; JARID2; MMS19; MED24; SMAD1; PIAS2; CRY1; KDM5A; ZNF24; FLNA; HSF2; DNMT3B; CBX3; SMAD2; KDM2A; ASH2L; ZNF587; ZNF551; CUX1; ATF5; FOXC1; ID2; ZSCAN18; ING3; PIR; SFPQ; SOX9; HLTF; ZIC1