Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68888	Isoreserpine	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	HMG20B; JUND; RHOA; ABL1; MTA1; SREBF2; TP53; NFKBIA; PBXIP1; AIP; SAFB; SMARCD2; ZNF787; RFXANK; TRIM28; SND1; SLC2A4RG; JUP; MYBL2; RELB; SCAND1; SIAH2; RXRA; NELFB; PARP1; ZNF711; MNX1; CNOT3; GATA3; EZH2; NR1H2; KLF6; CAMTA2; MITF; EHMT2; MSC; ZNF205; SATB2; TCF25; FOXL2; PCBD1; DDX17; SIN3B; ZNF8; NRIP1; BCL6; ALX1; RUVBL2; ZNF580; TXNIP; AR; ZNF835; MED24; ZNF274; KAT5; E4F1; CHD8; PHF1; HIPK2; SATB1; THRA; BNC2; ZNF227; HLX; BTG1; VGLL4; HOXA11; NOC2L; SMARCA2; SMARCB1; HDGF; FOXO3; RING1; RBL2; HEY2; KLF9; IRF3; ZHX2; TCEB2; ZNF264; POLR2A; MLXIP; NANOG; CEBPB; OSR2; MYRF; EMX2; ZNF500; CALR; ZFP36L1; LITAF; TCF7L2; ATN1; CBX7; PTTG1; ARID5B; HOXB2; SOX9; PITX1; CERS4; MAFB; SOX13; CAPN15; TCEA2; IRF9; ESR1; SALL1; SPDEF; NFIL3; GATA6; TSC22D1; FOXG1; MYCN; UBE2I; IRF6; HMGB3; ZNF331; ZIC1; MEIS2; WT1; KDM5D
Down-regulation	140	ZMYM2; DMTF1; FHL2; BRCA1; PSMD9; SSBP2; SMARCA5; TRIM22; TFDP1; TRIM29; ING2; E2F8; GTF3A; ATF2; RNF138; ZNF354A; BRCA2; PMS1; ZBTB11; COPS2; MYC; RAN; ZNF195; ZNF12; RNF6; CHD9; USP22; ZNF131; IRF7; UBE2B; TSG101; ZNF107; BAZ1A; RUNX1; BCOR; ARID3B; SP100; SAP30; ECD; TRIM24; ZNF7; MTDH; CHD1; HOXD1; KAT6B; RBBP8; ZNF273; NCOR2; TAL1; TCFL5; SIX1; PHF20; NFIB; FUBP1; COPS5; SOX4; NR2C1; SMARCD3; NFYB; TAF1D; NFE2L1; BAZ2B; KLF10; CRK; ASCL1; BASP1; NKX2-1; NUP62; SNW1; MGA; TAF10; DNAJC2; NAB1; ZNF84; PATZ1; TAF9; PBX1; MECOM; ZEB1; TBL1XR1; CREB3; RNF10; CREB1; C1D; ZNF281; ZNF232; TLE1; ZNF217; TOB1; ZBTB1; LEF1; ZNF443; MBD2; RB1; BRIP1; MED6; ZNF160; RNF111; HMGA2; ZNF189; HMGN3; NPAS2; ZNF24; BTAF1; ZNF587; ZNF140; ZNF623; MEIS1; KLF5; ZZZ3; VEZF1; CHD7; HMG20A; BBX; CTR9; ATF1; MTF2; CCNH; WWC1; ZMYND8; REST; TBX3; ZBTB18; ZNF117; BRD8; BCLAF1; TSC22D2; SMAD2; DACH1; BIRC2; ARID4A; SFPQ; CBFB; ATF3; ID3; CRY1; PEG3; YWHAB; PIR; IRX5