Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68858	Ibudilast	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	RELB; GATA3; RHOA; BHLHE40; SMARCD2; BCL3; ZNF223; CDX1; ABL1; NRIP1; SND1; AIP; SLC2A4RG; TAF4B; RFXANK; MYBL2; GMEB2; PBXIP1; MTA1; PPARD; THAP10; ZNF552; RXRA; CNOT3; RERE; ZNF816; ZNF227; HMG20B; ZNF571; BCL6; LHX3; JUP; ZNF226; HMGXB4; HOXB2; FOXL2; CAMTA2; HLX; TWIST1; NR1H2; JUND; KLF7; PCBD1; BNC2; AR; ZNF85; NAB2; MITF; EMX2; EZH2; SPIB; KLF6; TRIM25; TAF9B; CEBPB; VPS72; HIPK2; SCAND1; ZNF222; ZNF711; HMBOX1; PHF1; RXRB; HOXA11; ZNF835; ACTL6A; HINFP; KAT5; ESR1; IRF9; MED15; MED24; LITAF; SIAH2; NELFB; KDM5C; NKX2-2; ATF6; KLF9; JUNB; NR4A3; ZNF264; ALX1; ZBTB16; ZNF331; E4F1; BRF2; TTF1; SOX17; ZNF512B; ZNF253; FOXO1; MED21; CREBL2; IRF5; TP63; BRD4; JUN; TXNIP; CALR; RBPMS; ATN1; TRPS1; HDGF; CBX7; SOX13; HDAC9; MYRF; ARID5B; KLF4; PLAGL1; IRF2; CREB3L1; CAPN15; TFCP2; ZNF580; PGR; PFDN5; ELF4; SPDEF; HBP1; ZNF43; FOXO3; MAFB; TLE4; PITX1; ZNF91; HOXA5; MLXIP; OSR2; RORA; UBE2I; MEIS2; IRF6; WT1; TCEA2; NFIL3; IFI16; GATA6
Down-regulation	176	ZMYM2; DMTF1; FUBP1; SMARCA5; TLE1; TRIM24; PATZ1; TFDP1; ING2; BAZ2B; SOX4; USP22; ZNF672; BCOR; PMS1; FHL2; MTDH; RNF138; CNOT1; WDHD1; NFIB; BASP1; RCOR1; E2F8; SIX1; BAZ1A; ZNF423; BRCA2; MAML1; NFYB; KDM5B; PHF20; ZNF131; PRMT2; ZBTB18; NR2C1; E2F3; BRCA1; CEBPZ; MED20; CHD9; ZBTB1; TBL1XR1; PUF60; BTAF1; ZBTB11; ZNF7; HMGA2; RUNX1; RAN; PSPC1; RNF6; NFE2L1; RNF10; SOX12; CLOCK; NFATC3; SAP30; CCNA2; TCFL5; RREB1; BRD7; RNF111; TAF1D; GTF3A; CRK; CDK8; MEN1; RBBP5; ZNF107; HNRNPD; CHD1; HOXD1; IRF7; MBD2; RB1; NUP62; GLI2; FOXN3; SMAD4; TCF7; SNW1; NCOA2; ATF7IP; ZNF24; NCOA6; TRIM29; HES1; KAT6A; PSMC3IP; TERF2; ASCL1; ETS1; TOB1; HMG20A; VEZF1; ZNF281; MGA; TCF12; STAT3; DACH1; PQBP1; TAF10; CREB3; PBX1; KLF10; LEF1; ZNF12; ATF5; ZNF146; HMGN3; WHSC1; TLE2; TULP4; NAB1; ZNF302; GABPB1; NPAT; HDAC6; CHD7; SMARCE1; BRIP1; PBX3; BRD8; YBX1; FLNA; PAWR; RFX5; NR2F1; WWC1; ZNF232; HTATIP2; PEX2; TERF1; CBFB; ATF3; ZBED2; REST; HIRA; TGIF1; CUX2; ARID4A; BATF3; RBBP8; SMARCD3; ID3; ZZZ3; ZSCAN31; FOXJ3; NKX3-1; DPF2; MEIS1; TSC22D2; CTBP2; UBP1; POU2AF1; SMAD2; ZNF83; MTF2; TAL1; CUX1; ELK3; PHIP; TBX3; MYCN; CCNH; CTR9; BCL11A; CRY1; SFPQ; MYB; HLTF; TBPL1; KDM5D; IRX5; ID1