Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68851	Midostaurin	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	NFKB2; JUP; NFKBIA; PNRC1; TP53; KAT6B; JUND; ZNF770; MKL1; BTG1; INSM1; ZNF787; NFIX; HES1; SMARCA2; PKNOX2; AIP; ZNF331; LHX2; RHOA; PHF1; MTA1; PDLIM1; HSF1; KLF6; CNOT3; ZHX2; LITAF; DDX17; RFXANK; MYT1L; NAB2; MAFF; JAK2; BRD4; SCAND1; PRDM14; ZNF688; ZNF205; FOXO3; EP300; NANOG; NR4A3; E4F1; SPI1; CREM; NR4A2; MXI1; NRIP1; ING4; PBXIP1; CALR; ATOH1; SATB2; EN1; KLF7; ABL1; HLX; NR1H2; VGLL4; BHLHE41; JUN; RELB; CEBPB; TCF21; HDAC9; ZNF500; ZFPM2; ZNF224; HIPK2; ZNF444; HIRA; FOXL2; REL; ZNF264; TCEB2; RBL2; PEG3; SMARCA1; TXNIP; BNC2; SSBP3; TP73; ZNF667; FOXF1; ZBTB20; CERS4; ESR1; MED15; FOXF2; TULP3; ZNF580; PAX6; CDIP1; TFEC; SOX13; CREBL2; HBP1; TCEA2; MAFB; PGR; FOXG1; TOX3; PITX1; IRF6; HOXA11; HDGF; TFCP2; MED24; NFE2L3; KLF9; CCNH; EMX2; TRPS1; ATF5; TOX; TFAP2A; MEIS2; BRD2; UBE2I; ZNF91; KLF11; MYBL1; NFIL3; TRIB3
Down-regulation	205	IKBKAP; DMTF1; ZMYM2; GTF3A; ING2; SMARCA5; BRCA1; SIX1; FHL2; NUP62; ESRRA; MAML1; NRBF2; HMGA2; RNF6; RUNX1; MED7; PLAGL2; CDK7; TAF1D; MYC; ZNF107; EGR2; HDAC6; DNAJC2; ZNF7; ATF7IP; ECD; TRIM22; XBP1; KAT6A; BCOR; CHD9; CHD1; ZNF195; ZNF354A; ZNF12; WDHD1; CEBPZ; RNF138; TAF9; ZNF24; HDAC3; ZNF672; CCNE1; IRF7; SPEN; ZNF45; ZBTB1; ZNF443; CDK8; ZBTB11; DEK; TCF7; NCOA4; LEF1; ETS2; EED; BAZ1A; PMS1; ZNF131; STAT3; RCOR1; TAF7; MGA; ADNP; BAZ1B; ZNF273; LIMD1; SSRP1; MYNN; ZNF532; MYCBP; DR1; ZNF84; PATZ1; ZNF143; PSPC1; PKNOX1; ZNF468; TAF10; CCNA2; ITGB3BP; TRRAP; RBBP8; ZFP64; TCF4; TCF12; CREBZF; NAB1; TRIM29; MED6; MEN1; RAN; SNW1; ZNF146; CREB1; SAP18; MAGED1; SP140L; NCOR2; PREB; ZNF22; C1D; FUBP1; ASCL1; PSMC3IP; CRK; ZNF3; E2F8; UBP1; BRIP1; PSIP1; RNF141; ZNF23; ZNF232; ENO1; BCL10; ZNF32; TOPORS; ZNF202; RB1; ELK1; SOX4; BASP1; SMAD3; NFYB; HMGB1; SERTAD2; HOXD1; REST; BRPF1; ID3; FOXN3; REPIN1; HNRNPD; NPAT; ZNF606; TRIP6; CRY1; CBFB; SMARCD3; RNF4; HIPK1; SMAD2; SMAD4; ZNF267; TSC22D4; ZBTB18; BCLAF1; ZNF189; RBM14; NFYA; ZNF217; BTAF1; ETV1; KLF10; BACH1; MAX; BMI1; WWC1; CTR9; STAT1; EGR3; MNAT1; RNF111; ZNF329; ZBED1; ARNTL; ERBB2; ZNF14; BLM; KDM5D; HOXC6; BRD8; TSC22D1; CBX3; BIRC2; FOXJ3; SUB1; SFPQ; HMGN3; CUX1; SMAD1; TERF2; VEZF1; ZNF134; HOXB7; NR2F1; GTF2IRD1; ELK3; EDF1; HLTF; MEIS1; TBX3; YWHAB; DNMT3B; PIAS2; NKX3-1; PURA; IRF8; TBL1X; ID1; ZSCAN18; ZNF586