Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68849	Flunarizine	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	182	EGR1; GATA3; SLC2A4RG; CNOT3; HOXB2; CEBPD; JUP; ESR1; PPARD; BCL6; NFIX; RELB; GBX1; LHX3; NR3C1; VPS72; MITF; PKNOX2; CHD8; CALR; KLF9; PBXIP1; HDAC9; ZNF770; EMX2; GMEB2; FOXK2; CBX4; JUND; NAB2; NR1H2; MTA1; RHOA; SOX17; MAFF; HLX; PMF1; HSF1; E4F1; AIP; SETDB1; TOX4; ZNF223; TOX; ZBTB16; HMG20B; HOXD11; BNC2; FOXA2; TCFL5; TAF5L; RFXANK; PROP1; HOXB7; TP63; KDM5C; MNX1; CBX6; MYRF; MEOX2; ZNF8; CAMTA2; ZNF239; FOXF2; NFATC4; CREB5; THRA; ZNF711; SPDEF; KLF13; TXNIP; MED15; PRRX1; SMARCB1; SRCAP; HDAC5; TLX3; LZTR1; BTF3; SIX6; SHOX2; PRDM14; HMBOX1; ZHX2; CAPN15; DDIT3; PHF1; ZNF835; SIN3B; POLR3C; RXRB; BARX1; NR4A1; INSM1; TRPS1; CDC5L; ZNF444; HOXB5; TULP3; E2F4; MED21; SCAND1; HOXD10; RING1; ING4; GATA6; PRDM2; KLF7; BTG1; CERS4; RXRA; HIPK2; ETV1; ATF6; BANP; FOXO1; PCGF3; FOXL2; AR; HOXA11; FOXO3; ZNF224; ZNF264; ZNF500; ERBB4; BRD4; FOXG1; ATN1; SPIB; VGLL1; IRF9; NR1H4; TCF7L2; MLXIP; CITED2; SALL2; ZNF580; NKX2-2; PGR; MYCL; HDGF; SOX13; ZNF589; HBP1; ZNF331; MED24; DLX5; ARID1A; WWTR1; ZIC1; HOXC10; CBX7; CEBPB; ZNF512B; RBFOX2; ZBTB20; IRF6; ZNF91; SIAH2; ATF5; PNRC1; LOXL2; CUX1; NFIC; NR4A2; PITX1; ST18; HOXB6; TWIST1; OSR2; ATF3; EGR3; UBE2I; HEY1; MAFB; WT1; HOXA5; TCEA2; MEIS2; TRIB3; NR2F2; NFIL3
Down-regulation	237	DMTF1; FHL2; SMARCA5; BRCA1; PMS1; TFDP1; BAZ1A; BASP1; SSBP2; SOX11; HMGA2; RAN; WDHD1; SOX4; ARID3B; NFIB; BAZ2B; SAP30; ZNF131; CHD9; SP110; SNW1; PATZ1; ZMYM2; TBL1XR1; USP22; ENO1; RNF138; ZNF672; NFYB; MAML1; NRBF2; CEBPZ; SP3; PSMD9; TDRD3; ZBTB18; ZFP30; PSMC3IP; ZNF281; PUF60; E2F8; HSBP1; ZNF146; ITGB3BP; ZBTB11; VGLL4; TRIM22; IRF7; RBBP5; CHD1; NUP62; CNOT6; ATF1; BRCA2; BCOR; ZNF84; ZNF302; RNF10; ING2; ZNF107; FOXN3; MED7; TAF10; REXO4; TCF4; ECD; WHSC1; CRK; MBD2; TAF7; ZBTB1; HDAC3; BAZ1B; PBX3; RFC1; PQBP1; PBX1; MTDH; RNF6; ASCL1; BRD8; NR2C1; CREB1; CBX5; MGA; BTAF1; GTF3A; DNAJC2; LIMD1; TRIM24; ID4; CBFB; KMT2A; ZNF248; SETD3; SMARCC1; STAT1; PLAGL2; FUBP1; CDK8; YBX1; ETS1; TAF1A; ZNF3; BCLAF1; ZNF23; HMGN3; KDM4A; UBE2B; VEZF1; NCOR2; TRIM29; DRAP1; GABPB1; SMAD4; RB1; BMI1; ZNF273; CCNA2; ZNF140; CENPF; RBBP8; UBP1; MEOX1; ELK3; SUB1; PSIP1; HNRNPD; CNOT1; KDM5B; SMAD3; TBP; RCOR1; ZNF184; SP100; HMG20A; ZBED1; STAT3; MED6; XBP1; ETS2; CREB3; RBBP4; CTNNB1; ZNF267; SMAD2; EP400; WWC1; HDAC2; RCOR3; ZFP64; CTR9; RUNX3; NR2F1; ORC2; MEIS1; TRIM27; ZNF217; FOXJ3; FLNA; ID3; ZNF24; TRRAP; ZNF32; BRD7; SMARCE1; EED; MAF; BBX; ZNF232; PBRM1; REST; RFX5; KLF5; BATF3; BRIP1; RNF141; TOB1; PTTG1; TULP4; ZNF14; ZNF423; CRY1; BCL10; ZZZ3; MYB; YWHAB; HDAC6; HDAC1; TBPL1; ZMIZ2; ZSCAN31; ZBED2; DDX5; NCOA1; RBM14; DACH1; TRIP6; ING1; REPIN1; NKX3-1; IRF4; CBX3; ZNF652; TGIF2; PEG3; KDM5D; DPF2; ZNF443; TSC22D2; MYCBP; RYBP; LPIN2; HMGB3; IRF1; ARID4A; LIN28A; AFF1; SFPQ; HTATIP2; DLX2; PIR; MTF2; POU2AF1; MYCN; DNMT3B; TBX3; EYA1; PIAS2; TSC22D1; MAGED1; HLTF; KDM5A; HMGA1; VDR; ZNF586