Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68819	Digoxin	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	229	FOS; CNOT3; HMBOX1; ZNF430; PPARD; CBX4; JUP; ESR1; BRD4; CDX1; ZNF335; DDIT3; ZNF394; PEX14; PHF1; KLF9; HLX; HDAC5; NR4A3; HDAC9; POLR3C; ZNF93; SNAPC4; AFF4; NR0B2; NEUROD2; NR1H2; AR; CSDC2; SUPT6H; PBX2; ZNF34; LHX3; CREB3L2; IRF9; NAB2; JUN; MED25; ARID4B; ATOH1; PRDM14; ZNF85; MEF2D; ZHX2; REL; NCOA2; ZNF44; HOXB2; KDM5C; KLF7; ESRRG; WT1; E2F4; ZNF331; PROP1; HSF4; TOX4; ZNF91; IRF6; CDK7; E4F1; ZNF235; ZNF345; RAD21; TULP2; MXI1; SUPT5H; BAZ2A; JUND; ZNF669; DBP; HSF1; GBX1; FOSL2; MED17; TGFB1; BANP; BNC2; ZBTB44; ZBTB17; HBP1; CHD4; USP16; ERBB4; CDIP1; ATF3; ZNF354A; TULP3; CBFA2T3; NR5A1; LDB1; NFE2; CCNT1; SKIL; ETV3; RRN3; TWIST1; FOXK2; CALCOCO1; ZNF273; SIN3B; ETS1; ZNF10; BCL3; GMEB2; RARG; ZNF611; TFAP2A; CAMTA2; EN1; TRPS1; SMARCA1; KLF15; NFE2L2; GATA1; BCL11A; ZNF544; ACTL6B; CHD8; TXNIP; FLI1; SPDEF; BARX1; SKI; CDC5L; ZNF701; DLX2; NRIP1; ZNF43; ZNF350; PIAS1; SATB2; PHIP; LITAF; PNRC1; YAP1; HOXB5; SIX6; FEZF2; ZNF239; RSF1; CEBPD; INSM1; ELF4; RELB; ZBTB43; CEBPB; TP73; ZNF224; ZNF500; RING1; KDM5B; HHEX; SHOX2; EMX1; ZNF117; INSR; VPS72; FOXF2; IRF3; ARID5B; ZNF136; ZNF682; ZNF556; ZNF195; IFI16; OSR2; IRX4; VGLL1; KDM5A; NR1H4; HDGF; MLXIP; MTF2; SIX3; TP63; ZNF253; PGR; ZNF589; GATA6; NCOA3; NR5A2; NR4A2; ZNF665; TFDP2; PBXIP1; SOX13; NR4A1; RUNX3; ST18; KLF13; CITED2; MED13; ZNF141; ZFPM2; NR1D2; TFAP2C; NR3C1; FOXE1; BNC1; MAFG; FOXO4; GATA2; VDR; AEBP1; PAX5; HOXC10; PCGF1; NFAT5; BACH2; TTF2; RYBP; ZNF264; EMX2; MEIS2; SNAI2; TCEA2; NFE2L3; HOXD1; FOXO3; ZBED2; BTG1; TRIB3; HTATIP2; SSX1; KLF6; MYBL1; IRX5; DACH1
Down-regulation	256	TP53; PATZ1; PARP1; NUP62; PMS1; PSIP1; SMARCA4; CBX5; CCNA2; SUV39H1; HMGA2; BRCA1; NFIB; ING2; HDAC6; TRIM28; MAGED1; ZNF32; URI1; SMARCC1; EZH2; BRD3; SMARCE1; SOX11; GTF3A; SMARCA5; TBL1XR1; ITGB3BP; PHF20; ZNF532; DDX54; SAP30; RBBP4; E2F5; NFYB; CENPF; ZNF248; PQBP1; CBX3; ZNF672; TAF1D; ZNF146; RAN; CENPB; TADA3; CCNE1; HDAC1; PMF1; RNF138; NPM1; SOX4; RNF141; TCF4; XBP1; SP3; ZNF266; TLE1; IKBKAP; UBTF; ZFP30; ENO1; ZBTB14; PKNOX1; TSC22D3; PREB; HSBP1; USP22; BASP1; ETS2; MED7; LIMD1; HMG20A; ZNF84; ZFP64; PCBD1; MAF; TRIM27; BAZ1B; MYCBP; MLX; HDAC2; BAZ1A; TRRAP; ELK1; ZBED4; E2F6; NR2C1; ZBTB1; TCF12; EDF1; ZBTB18; REXO4; PBX1; BMI1; NELFB; APEX1; HNRNPD; CARM1; SCAND1; KAT8; ZBTB24; HMGXB4; TAF12; ZMYM2; REPIN1; NONO; YBX1; WDHD1; TAF9B; ZBED1; PEX2; ZNF443; RBM14; STAT1; PCGF2; SREBF2; ATF4; BCLAF1; SIX1; TCF20; SMARCB1; ASH2L; EWSR1; PIR; MED24; ID3; CTNNB1; CHAF1B; RBBP7; LOXL2; NCOA4; TRIM29; NCOA6; SMAD4; TAF10; ZNF184; HOXC6; ZMYND11; LPIN2; CREG1; MGA; NAB1; CARHSP1; PSPC1; MAFB; CNBP; FUBP1; MDFI; NEDD8; ORC2; ELF5; NFE2L1; NR2F2; ISL1; DEK; THAP1; UBP1; EED; TRIM32; HES1; WWC1; SMAD2; ZNF302; BIRC2; HDAC4; KDM5D; HMGN3; PUF60; TAF7; PRKDC; BRD8; NRBF2; NPAT; TGIF1; CBFB; BATF3; KDM4A; HMGB2; RUVBL2; ID1; ATF1; PBRM1; PHF2; MAZ; USF2; PHF8; ZNF24; HDAC3; RNF14; PIAS3; POU3F2; ZNF189; DEAF1; NCOR2; MEIS1; SUB1; NR1H3; XRCC6; C1QBP; ZNF131; ELK3; DDX5; SND1; GTF2IRD1; CHD7; NKX3-1; WHSC1; ZBTB11; MED1; TFDP1; ZKSCAN7; CTBP1; TSC22D1; RNF4; TRIM16; SFPQ; WWP1; ZNF528; DNAJC1; TBL1X; HEY1; SOX2; TOX3; ZNF783; FLNA; HMGB3; THAP11; ZNF3; MECOM; TBP; REST; ZMIZ2; HLTF; VGLL4; EGR2; SREBF1; SAP18; SATB1; SMAD6; MBD2; WWTR1; LEF1; ASCL1; SMAD1; TOB1; YWHAB; ZMYND8; KAT6A; CTR9; ZIC1; CCNC; CRY1; MYCN; RFX5; NFIL3; TBPL1