Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68777	Chlorthalidone	GSE92742	NPC	Human	24h	10uM	EID0375

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	PPARD; GATA2; AEBP1; NFATC3; ZNF771; LHX3; TRPS1; NR3C1; BARX1; MDM4; ETS1; ZNF444; CDX1; ZNF816; JUP; NR0B2; HMX1; NKX2-1; HLX; CEBPE; MED14; TSG101; WIZ; VPS72; FOXN2; ZNF552; CDIP1; IRF6; TWIST1; TSHZ2; FOXO1; MECOM; E4F1; L3MBTL1; MLXIPL; RFXANK; GATA1; KLF7; ZNF195; MEOX2; HIRA; SUPT5H; HOXB5; KDM5C; ZHX2; ZNF580; SUPT6H; ZFPM2; SHOX2; TCEB2; E2F4; NFE2; FOXF2; SOX13; KLF9; ELF4; ZEB1; ZNF671; NR1H2; PHF1; TCF7L1; SKI; JUND; ESR1; SP140L; HDAC9; TCF21; HIPK2; LMCD1; CEBPD; FOXE1; ZNF224; FOXF1; RBFOX2; AR; BNC2; ZBTB20; PAX5; KLF13; HOXB2; BACH2; TFAP2A; IRF9; CALR; CUX2; ZBED2; FOXD1; POU2AF1; INSR; ATF5; JUN; SMAD1; LITAF; ZNF117; TCEA2; TRIB3; HEY1; IFI16; IRF8; VDR; MEIS2
Down-regulation	198	IKBKAP; USP22; ZMYM2; ZNF12; KAT6B; ING2; NUP62; DR1; PATZ1; CRK; ZBTB18; SMARCA5; ZNF266; SAP30; PMS1; PSIP1; BBX; CENPB; ZNF184; BAZ1A; CBX3; BRCA1; NRBF2; RNF4; ZBTB11; CNOT1; ZNF529; MAML1; ZZZ3; EED; TAF11; KLF10; CHD1; ZBTB38; TRIM28; TRIM24; RNF6; SUV39H1; PHF20; XBP1; E2F6; ZFP30; ZNF84; THAP1; ZKSCAN1; SPEN; ZNF562; TLE1; SMARCA4; ZNF148; MED7; TCF4; HDAC6; TOPORS; ZEB2; ZFP64; DNAJC2; MED6; HIPK1; ZNF7; PIAS3; UBE2B; ZNF248; CBX5; CDK8; ZSCAN12; MTF2; ZNF468; RREB1; TRIM22; FOXJ3; E2F3; ZNF44; SMAD3; FOSL2; NFIB; NFYB; HES1; CENPF; BCL10; VEZF1; TBL1X; SIAH2; TAF6; CHD9; HMGA2; SP3; TBL1XR1; STAT1; ATF7IP; TAF1A; PSPC1; ZNF672; ZNF131; ZBTB1; MAGED1; TOX3; MAX; TTF2; LIMD1; BMI1; ORC2; TRAK1; REPIN1; RNF138; CNOT6; CREB1; KLF4; HSBP1; PAXBP1; BASP1; PBX1; ZMYND8; ZNF107; TOB1; SFPQ; TSC22D2; OLIG2; PSMC3IP; ITGB3BP; FLNA; TRIM29; ATF1; ZNF443; KAT7; EGR3; HOXC6; BCLAF1; EGR1; BIRC2; ZNF32; WHSC1; HMGN3; WWC1; ARID4B; DEK; TRRAP; USF2; NRIP1; HDAC4; REST; ZNF189; UBP1; RBM14; ZNF140; ZNF532; ZNF217; SMARCA2; C1D; MYCBP; ZMIZ2; NCOA1; DLX5; NR0B1; DNMT3B; ILF2; ID3; SPDEF; MED1; BRD8; BATF3; BRPF1; ID2; ZSCAN18; ZNF14; GMNN; ETV1; HIC2; PCGF2; FOXG1; NKX3-1; DNAJC1; RBBP4; PIR; ETS2; C1QBP; TBPL1; TRIM16; DDX5; ASH2L; HLTF; BRD2; MYCN; CBFB; TBX3; NFIL3; MSX1; ING3; AHR; YWHAB; JARID2; ERBB2; KLF2; NR2F2; CRY1; CTR9; ID1; IRX5