Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68733	Dantrolene	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	164	PPARD; VPS72; THAP11; TRIB3; NR5A2; GATA2; SPDEF; PRDM14; MED25; ZKSCAN4; SOX18; ELF4; PBXIP1; ZNF444; ATF3; SETDB1; HIC2; ZNF232; ZNF835; GON4L; ZNF688; MKL1; OVOL2; PRDM13; AR; ZNF816; HOXD1; ZNF141; TSHZ2; HBP1; HIPK2; BRD7; AIRE; PIAS4; CXXC1; SOX13; ZNF467; CCNH; CEBPD; E2F8; GATA6; ATN1; TAF4B; NR0B2; IRF9; ZNF133; RARG; HOXD3; ZNF394; ZNF79; TCF7L1; ZIC3; CTCF; SRCAP; BNC2; TWIST1; NFRKB; BPTF; PEX14; TFAP2A; ZNF652; PCGF3; CNOT3; PAX6; ZNF415; ZNF33B; ZNF665; DR1; FOXG1; CAMTA2; PFDN5; CERS4; CDIP1; ARID1A; ZNF711; SOHLH2; NR1H2; RERE; KLF7; DBP; TEAD4; FOXK2; ZNF580; ZNF623; IRF8; MAK; SHOX2; ZNF43; HOXB6; FOXO1; KLF13; AGO2; TTF1; ZNF124; IRF6; HLX; ACTL6A; ZFP36L1; TP53; MED17; SOX17; JUNB; TTF2; PBX3; NUP62; NEUROD1; PCGF1; ZNF544; MED15; HDGF; KLF11; ESR1; MXI1; NR2F1; GFI1; HOXB2; WNT4; WIZ; ZNF117; GRHL2; E2F5; HIRA; SALL2; TFAP2C; ATF5; MKL2; VDR; MNDA; NFE2; ST18; MEIS2; YAP1; AES; TCF21; BTG1; ERBB4; HMBOX1; TGFB1; KAT2B; EMX2; HOXB7; GTF3A; ZNF264; TCEA2; HOXB5; SOX11; ZNF589; WT1; HDAC9; NFATC4; BCL11A; ZBED2; HEY1; EGR1; TFDP2; FOSB; MYRF; ZMIZ1; DLX2; AHR; SOX9; TLE4; OSR2; MECOM
Down-regulation	156	USP22; RFX5; ATF1; BBX; PPARGC1A; CTNNB1; PHF8; ZNF329; EP400; RAN; PHF2; SNW1; BRCA1; USF2; ZBTB38; YWHAB; EDF1; ING3; HMGA2; NFYB; NRIP1; MYT1; SMARCE1; SMARCC1; PBRM1; BRD8; NPAS2; ZNF672; HMGA1; XBP1; SIAH2; MLX; MITF; FOXC1; ETV5; MED13; ZBTB11; SFPQ; TSC22D2; HSF2; SREBF2; PHIP; KLF2; RBM14; CBFB; ASCL1; SIM2; DDX54; BRD2; TBP; FOXJ3; ZNF148; RBBP5; MAGED1; UBP1; HMG20A; DDX5; ETV1; PATZ1; SUB1; LPIN2; ERBB2; HNRNPD; HDAC6; PRKDC; TAF7; ASH2L; KMT5A; CREB5; TLE1; NR1D2; ORC2; ZHX3; RBBP4; PTTG1; CREB3L1; TCEB2; ZEB2; SMARCC2; CRY1; RNF10; BTAF1; NFIL3; PQBP1; BIRC2; ZMYND11; HMGN3; ZMIZ2; DRAP1; SAFB2; YBX1; ZSCAN18; SATB2; ZNF84; NR2C1; ZNF443; ING1; BMI1; SALL1; TAF1D; CBX3; TBL1X; CHD1; HMGB2; EP300; KLF5; ZNF281; MDM2; ING2; SNAI2; NFAT5; HOXC6; BAZ2B; TFAM; EGR3; VGLL4; POLR2A; ZBTB20; ETS2; TBL1XR1; RELA; DNAJC1; PURA; CITED1; SMARCA5; SOX10; SMARCA2; CTR9; MSX1; NKX3-1; ZNF131; NR4A1; MAFF; DDIT3; ID2; BASP1; ENO1; HIVEP2; ZBTB18; CHD7; JARID2; FOSL2; MED1; MYB; EED; TAF10; LEF1; HLF; ZNF160; PLAGL1; KDM5D; TXNIP; TRIM29; NFKBIB; CEBPA; NFKB2