Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68727	Leflunomide	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	TCFL5; THAP11; HOXC10; PRDM2; HCFC1; TERF2; PAX9; DAXX; ZNF282; CARF; ZNF444; ARID1A; ZNF787; MYBL1; ZBTB14; ZNF552; UBE2L3; AES; HHEX; CIZ1; SATB1; PIAS4; UBTF; CDK9; CBFA2T3; ARNTL; RING1; KDM5D; SP3; ZNF24; TXNIP; ID1; RBPMS; TRIM28; RUVBL2; ZBTB18; HOXC6; FOXF2; ADNP; IRF3; ZNF34; MAZ; AIP; JUN; NR1H4; PCGF2; ELK3; TAF12; MKL2; ZNF165; NCOA6; CBX4; MEN1; INSR; ZNF544; TBL1X; GTF3A; CNOT3; ZNF623; NFE2; WNT4; TAL1; ST18; CREB3L2; PITX1; FOXE1; EGR1; TBL1XR1; GATA6; CALR; CEBPA; NKX2-1; FOXD1; ATF5; TRPS1; ZNF652; SLC2A4RG; ZNF589; BCL3; MYC; RUNX1; TGFB1; FLNA; TCF4; ERBB4; MTF2; SOX9; PURA; DNMT1; BCL11A; CDK7; ZBTB16; HMG20B
Down-regulation	116	TLE1; USP22; ATF1; HMGA2; UBE3A; SIX2; BASP1; ATF3; SMAD7; MEOX2; PEX2; MED4; KLF13; ARID5A; ZNF331; KLF6; ETS2; RLF; MAF; PAXBP1; HOXA7; NRIP1; PTTG1; EGR3; PBRM1; ZIC1; RYBP; JUND; SNAI2; BMI1; CENPF; NR1I2; MITF; ZNF268; PAX5; LEF1; HMGB2; NCOA1; ID4; ZNF423; MEIS1; IRF2; PPARGC1A; ETV1; TCF21; YBX3; BTG1; ZEB2; NR4A1; AR; TFCP2L1; CBX3; EYA1; EHF; POU4F1; ZNF562; DACH1; EWSR1; SMARCD3; ITGB3BP; LPIN2; MYCL; PLAGL1; HIF1A; SSX1; SSBP2; AEBP1; KLF5; TMF1; CHD7; MDM2; HDAC9; FOXO1; IKBKAP; NR3C2; HMGB3; TOX3; RNF10; ZNF266; NKX3-1; JARID2; YEATS4; CCNE1; NFKB1; KLF9; RBBP8; NR2F2; MYCBP; ZMYND8; EED; FOSL2; KAT2B; MECOM; EYA2; ZBTB20; ZNF160; MSX1; NUP62; HEY1; EGR2; CREB3L1; WT1; PEG3; AHR; HOXA5; MNAT1; ETS1; SCAND1; DMTF1; ZNF721; ZNF274; PBX1; TCEA2; EMX2; NFKBIB; NFKB2