Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68720	Irsogladine	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	SMAD3; THAP7; ZNF282; SETDB1; HLX; TRIB3; TRIM22; ERF; ZNF131; HIC2; IRF9; SAP30; AATF; ZNF350; MXI1; HOXD1; ZNF768; ZNF195; LOXL2; ARID5B; RNF141; NR1H3; ZNF467; PCGF2; ZNF43; GFI1; ZNF165; HIRA; TDP2; KLF13; TFAP2A; USP21; TSG101; PLAGL2; SP100; CCNH; ZNF85; POLR3C; FOXL2; ID1; PAX5; BRD4; SMARCB1; MITF; FOXO1; ZNF532; KLF11; ZNF394; BACH2; HBP1; ZNF580; ZNF415; KLF3; TFDP2; VPS72; PIAS1; MED15; RUNX3; PCGF1; ZNF589; ZNF665; ZNF232; SOX9; SMAD1; TCF7L1; TFCP2L1; CRYM; MLXIP; HEY1; GATA6; KLF7; EGR1; ZNF281; FOXG1; EGR2; MYRF; ZNF91; MAFB; CBX7; IFI16; WT1; ZBED1; CDK2; ZNF430; DLX2; TBX3; TCEA2; ZSCAN31; BNC2; ID3; POU2AF1; SNAI2; HOXB6; TGFB1; CREB3L2; ERBB4; ZFP36L2; MECOM
Down-regulation	68	RFX5; SPEN; HNRNPD; ATF1; ZNF587; BASP1; NKX2-2; MED21; EDF1; PBRM1; CDK8; BATF3; SOX5; ZBTB32; CCNA2; BTAF1; MED13; DNMT1; NRIP1; ARID4A; CHD9; FOXO3; IRX5; RBM14; HSBP1; ING3; KDM2A; SATB2; TLE2; PSPC1; HSF2; ZMYM2; CHD1; ARNTL2; SMAD4; NAB1; DACH1; RBPMS; TOX; CDK7; BMI1; BCLAF1; CITED1; OLIG2; DNAJC1; TRPS1; ASCL1; NFKB1; KDM5D; CHD7; MYCBP; EED; ESR1; PLAG1; RXRA; SCAND1; MNAT1; MYB; HOXA5; MYCN; HMGB3; INSM1; BAZ1A; PBX3; ZNF721; NFKB2; NUP62; CEBPA