Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68717	Jak3-inhibitor-i	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	HLX; CREB3; ABT1; TRIM27; IRF9; TFAP2A; MXI1; VGLL1; GATA6; ZNF557; PBX2; TOPORS; DAXX; AES; ZNF304; MXD1; CDK9; PML; ATF3; TAF1D; C1D; YEATS2; JAK2; PSMC3; MAFB; RNF141; ZNF467; PCGF1; CRYM; ZNF350; CNOT6; PHF1; NFKBIB; ITGB3BP; ADNP; ZNF593; ID4; ZNF14; TCF21; KLF2; STAT4; YEATS4; HOXD1; ZNF177; SP100; TCEB2; DBP; MED7; WWC1; MED12; TP63; PEX14; DPF2; ETV5; IRF4; PAX5; ZNF165; KLF11; ARID5B; NAB1; MDM2; FOXD1; NR4A1; ID1; EGR1; ZSCAN31; ZNF136; CAMTA1; ZSCAN18; RBL2; ARL2BP; NFIB; TFDP2; ZBED2; IL16; BCL11A; CBX7; TGIF1; EHF; MNDA; PIAS1; SATB2; TCF7L2; POU2AF1; ERBB4; MYCL; TSC22D1; ST18; NFE2L2; HDAC9; CD3D; MKL2; BATF; TXNIP; FOXG1; CREB3L2; NKX2-1; TCEA2; ZBTB16; EGR2; EYA2; RBPMS; PIR; MEIS2; TRIM29; JUP; TGFB1; WT1; BHLHE41; CRK
Down-regulation	112	USP22; NCOR2; SPEN; SOX4; SIM2; PAXBP1; HOXA7; USF2; NCOR1; SUZ12; PRKDC; SMARCD3; SMAD7; ESR1; CIC; HDAC6; DNMT3B; MYT1; BRD3; GATAD2A; BTAF1; REXO4; CAPN15; PHF8; PBRM1; MAF; SREBF1; ZIC1; ZBTB7A; BCLAF1; CENPF; ZBED4; E2F8; ZNF331; EZH2; CDK8; PLAG1; TULP3; KDM2A; PATZ1; MED24; KAT2A; ZMYND8; CCNC; CBFB; CHD9; SFPQ; ZNF224; PRRX1; MYF6; HEY2; JARID2; HIVEP2; STAT5A; ZNF587; PITX2; RBBP7; HEY1; BTG1; TRRAP; ZFP36L1; DNMT1; PURA; DLX5; DEK; EP300; PBX3; DMTF1; CDK7; PAWR; BASP1; NPAS2; ATF4; IRF8; SALL2; PITX1; HOXC6; ZMYM2; KLF5; DDX17; CUX1; CUX2; TBL1X; DACH1; MAFF; POU4F1; NLK; MSX1; STAT3; ZNF160; ZEB2; HTATIP2; LEF1; ZNF721; ETV1; HOXA5; ZNF573; PCGF2; BRD4; NUP62; CREB3L1; CHD7; MAGED1; NR2F2; TOX3; EED; ZBTB20; ZBTB18; ZFPM2; ZNF274; CEBPA; ZFP36L2