Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68695	Icariin	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	64	E2F8; NR5A2; ZNF286A; TRIB3; AFF1; SSRP1; CERS6; PROX1; ZNF253; CUX2; TAF6; RNF111; ZEB1; CBX6; HOXC10; TCF12; BCL11B; RSF1; ZBTB40; ZNF384; DDX17; NONO; MEN1; PRPF6; TRIM28; RBPJ; MYCN; MKL2; HOXB6; SMARCA5; IRF7; KLF10; INSR; HOXB13; ST18; KDM5D; TBL1X; HAND1; TGFB1I1; ZBTB18; ATF7IP; FOXG1; GLI3; TWIST1; TEAD1; SREBF1; CARHSP1; TRIM24; ATF4; ZNF589; BAZ1A; SNAI2; HOXB2; SOX11; CTR9; BASP1; TOX3; PBX3; HDAC9; ZBED2; HOXC6; SOX9; MYRF; CRK
Down-regulation	70	RFX5; KLF2; ADNP2; TSC22D2; ATF3; CTBP1; HOXA7; EZH2; CTNNB1; ZEB2; CHD7; TOB1; FUBP1; NFYB; MYBL1; CBFB; TGIF1; NR4A1; PPARGC1A; HSF2; ARL2BP; POLR3C; YAF2; NR4A2; NRIP1; ZMYND11; SAP18; POU4F1; CHD1; HMGN3; SMARCD3; ZNF512B; HMGB1; GTF3A; KLF11; POU2AF1; RBBP4; TP63; RUNX3; LOXL2; MNAT1; ZNF423; BCL6; DDIT3; AEBP1; MTF2; TFCP2L1; NCOA3; CDK7; SOX10; TCF4; KLF5; YBX3; NR1D2; HOXA5; NKX2-1; TRIM29; SCAND1; TLE4; CITED2; ISL1; NR2F1; HMGB2; ID1; TCEA2; BHLHE41; ID3; NFKB2; EGR1; CEBPA