Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68662	Alprostadil	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	196	PPARD; SPDEF; PRDM14; PBXIP1; THAP11; NR1H2; JUN; EN1; TRPS1; LZTR1; GATA6; PDLIM1; TOB1; HIRA; TRIB3; IRF6; ATF3; SRCAP; ZNF688; ZNF223; ZNF816; GATA1; SSBP3; ZNF835; RAD21; ZNF665; CDX1; HIVEP1; ZNF165; BNC1; ZNF74; ZNF576; ELF4; MBD1; IRF9; CXXC1; VPS72; ATF6; SUPT3H; TAF9; THRB; TFAP2A; ZNF273; TOPORS; CERS6; LHX3; TP73; UBE2L3; STAT4; FOXJ1; FEZF2; OVOL2; ZNF264; CREM; ZKSCAN4; KLF11; ZNF668; SKIL; VDR; NOCT; ZNF222; ZNF552; ZIC3; ZNF141; SPI1; ZNF33B; PRDM2; TAF5L; RORC; RING1; CSDE1; CBFA2T3; ZNF180; RUNX1; SUMO1; NR2E1; ATOH1; MED15; TDP2; MYB; CBX4; CBFA2T2; TRIP11; ZNF253; HLX; SOX15; ERBB4; VGLL1; ZSCAN9; LITAF; PPP1R13L; ZNF43; ZNF394; MYBL1; TULP3; KDM4C; SP140L; SNAI2; MXD1; SIRT2; CCNH; ZNF91; ZNF652; FOXA2; ZBED2; ENY2; ARNTL; ZNF415; FOXF2; ZNF195; MED12; ZNF117; CAMTA2; AES; KLF13; NEUROD1; EHF; BNC2; FOXL2; KLF5; PHF1; MED14; GLI2; FLI1; BCL11A; ZNF573; TTF2; HSF1; SOX9; NFYA; KLF7; MAK; LIN28A; TP63; ZNF544; ARL2BP; MKL2; HDAC5; TCF21; GRHL2; RBFOX2; ACTL6A; AEBP1; FOXE1; NFE2L2; MEIS2; JUP; ATF5; TRIM29; ZNF44; HBP1; DEK; CEBPB; SMARCA2; JUNB; ZFP36L2; PBX3; PGR; PNRC1; ZMIZ1; ZBED1; CREBL2; TAL1; PAX6; CD3D; TCF7L2; ZNF589; DACH1; FOXG1; ZSCAN31; TCEA2; RORA; TBX3; INSM1; NFATC4; ZIC1; TOX; ZNF512B; ZHX2; TXNIP; KLF6; TCF7; FOSB; CDK7; DNMT1; PEG3; ID1; CALR; HOXA5; WT1; TGFB1; ST18; ETS1; TFDP2; BHLHE41; KLF9
Down-regulation	234	KAT6A; PUF60; SPEN; TCERG1; SNW1; SMARCC1; PSMD9; SALL1; RCOR1; HMGA2; TBP; RFX5; BRD8; CCNA2; RBM14; PHF8; RNF4; EDF1; NCOR2; FHL2; SUV39H1; LPIN2; MED4; USP22; KAT7; FOXJ3; RERE; POU2F2; DPF2; ARID4B; HDAC1; ERBB2; BMI1; TBL1X; NFKBIA; BRCA1; RNF10; EP400; ZNF148; MYT1; TSC22D2; SOX4; ELF2; ZEB2; HCFC2; TRRAP; SMARCE1; ETV4; ECD; EGR2; RHOA; DDX54; ATF1; DRAP1; POU3F2; HSF2; PSIP1; ZBTB11; KAT5; ENO1; PRKDC; ZNF516; ZNF146; TAF1D; PCBD1; HOXC6; TRIM32; CITED1; ZNF532; FOXO1; USF2; SP3; TCF15; PPARGC1A; ASH2L; POU2AF1; PCGF2; NR2F2; MAGED1; BBX; E2F2; YWHAB; RBBP4; ZKSCAN7; MED16; TRIM22; ZNF410; HNRNPD; NR0B1; NCOA6; PMF1; BIRC2; DAXX; DNAJC2; E2F6; UBP1; HDAC2; SFMBT1; BCOR; SP2; NFYC; TRIM28; GTF3A; PSPC1; DNAJC1; TSC22D4; PHF2; EGR3; RNF141; XBP1; BRD3; BASP1; BAZ2A; HMG20A; POLR2A; BCLAF1; SIAH2; ATF7IP; EYA1; PBRM1; MSX1; TADA2A; SAP30; FOXO3; POU4F2; PATZ1; BAZ2B; CRY1; HEY2; JARID2; NEDD8; KMT2A; ZNF212; BRD2; KDM2A; PAX5; MDM4; ZMIZ2; ASCL1; ZNF226; REST; CTR9; NFIL3; SFPQ; TSG101; SMARCC2; AATF; MTDH; BRPF1; NRBF2; ETV5; RNF14; CREB5; TBL1XR1; ADNP; TCEB2; SMARCA1; DMTF1; SMARCA5; HSBP1; HMGB1; NPAS2; HOXB6; ALX1; BATF3; ZNF443; ZZZ3; PTTG1; RB1; TCF12; TBPL1; HOXB7; POU4F1; ZMYND8; PIR; DDX17; MEN1; CHD1; ETV1; PRRX1; IRF8; MXD4; ZMYM2; SOX11; CENPF; MED1; PPRC1; NR4A1; TRIP6; TSC22D1; IKBKAP; PIAS3; SMARCD3; KDM5A; HLTF; SMARCA4; ZBTB38; SMAD2; EZH2; RNF6; HTATIP2; NFAT5; ID2; IRF4; POU2F1; CARHSP1; TGFB1I1; CBX3; FLNA; ELK3; MAFB; OLIG2; ZBTB18; NUP62; HOXB2; PBX1; TGIF1; FOXF1; TOX3; TAF10; HMGB2; ZBTB16; ZNF217; ISL1; HMG20B; EGR1; NKX3-1; SCAND1; NR2F1; TLE4; ZBTB20; NFKBIB; OSR2; NFKB2