Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68602	Midostaurin	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	169	FOXF2; BRCA1; TRIB3; NFATC3; MNDA; PDLIM1; ARID1A; IRF9; CEBPD; HLX; LZTR1; CCNH; ABL1; TFAP2A; VPS72; TP73; ZNF467; PRDM2; MXI1; ZNF354A; ZNF506; MNX1; ZFHX3; ZNF43; LOXL2; ATN1; TBX2; HIPK2; JUND; IRF6; SPDEF; HOXB1; SETDB1; CDX1; PCGF1; ZNF165; HIPK1; ZNF580; PBX2; SUPT6H; CALCOCO1; MYCL; MYBL1; SSBP3; ZHX2; ELF4; ZNF32; EPAS1; MED15; ARID5B; CIR1; CDIP1; FOXJ2; EHMT2; FLI1; PHF1; HMBOX1; POU2AF1; OVOL2; DAXX; LITAF; BAZ2A; VDR; RAD21; ZNF423; KDM4C; ZNF688; RING1; STAT4; NFX1; ZNF117; PAWR; RRN3; CRYM; GON4L; CNOT3; GFI1; CTCF; FOXA2; POU4F2; JUN; SHOX2; RFXANK; CEBPG; NR0B2; PSMC3; IRF3; TAF1; NFATC1; GATA6; SIX3; VGLL1; RCOR3; ZNF665; ZNF394; SUPT5H; ID1; CERS6; TERF2; AES; TOB1; RARG; MTDH; ZNF232; TCF7L2; TCF7L1; POLR3C; NFE2L1; ZNF652; PBX3; MED12; HOXB5; SOX13; PEX14; HHEX; TCF21; SNAI2; ZNF44; INSR; YAP1; SMARCB1; PPP1R13L; TP63; CEBPB; CAMTA1; ZNF195; TP53; BCL11A; GRHL2; AIP; CALR; HOXB6; ZBTB20; FOXD1; DBP; MAZ; IL16; MKL2; CREB3L2; RREB1; CBX7; COPS2; AHR; TGFB1; PIAS1; TCEA2; PNRC1; RUNX3; SMAD1; TAL1; MYRF; NFE2L2; ZNF264; TWIST1; TCF7; ZBTB18; LMCD1; TXNIP; BNC2; TRIM29; ID3; HOXB2; FOXF1; DNMT1; TBX3; ETS1; ZFP36L2; HOXB7; BHLHE41
Down-regulation	167	RUVBL1; HMGA2; USP22; ATF1; RFX5; MED4; WWTR1; PSIP1; LZTS1; PLAGL2; SMARCC1; DDX5; YWHAB; MED21; RAN; RBBP4; HSBP1; HDAC6; BRIP1; SMARCE1; DEK; STAT5B; MED13; HDAC2; FOSL1; PPARGC1A; NR2F2; MAF; ETV1; RBL1; ELK1; HNRNPD; ZEB2; NFIB; LPIN2; ZNF148; ARNTL2; TFAM; EWSR1; BBX; ERBB2; TRIM22; PATZ1; EP400; BATF3; YBX1; NRIP1; ZNF587; PBRM1; ING3; UBE2I; CRY1; NCOR2; PAX5; NRBF2; SIX1; L3MBTL1; CBX6; TRPS1; DNMT3B; E2F6; SND1; TRRAP; JARID2; ENO1; TLE2; TSC22D2; NFYB; SUPT4H1; CDK7; EGR3; TAF11; IRF8; BRD3; EN2; ZNF468; RBBP7; SAP18; BRPF1; NPAS2; BLZF1; MAFG; ZMIZ1; PSMC3IP; ZNF281; EDF1; ETV5; MED7; KDM2A; BASP1; EGR2; CBX3; DMTF1; REST; VGLL4; FOXG1; PRRX1; SCAND1; MED1; FLNA; PIAS3; MYCN; ZMIZ2; ZNF532; UBP1; NUP62; NKX3-1; KDM5A; ING2; MAGED1; ITGB3BP; EED; FOXO1; SSBP2; ZNF267; ZBTB1; DLX5; SFPQ; PCGF2; SATB2; IRF7; NR2F1; HMGN3; RXRA; HLTF; BLM; ATF4; PTTG1; XRCC6; BTG1; MNAT1; EZH2; ELK3; HOXC6; HTATIP2; NFKB1; MYCBP; NR4A1; MAFB; OLIG2; CTR9; CUX1; ZMYND8; TGFB1I1; NFIL3; MEIS1; HOXA5; MECOM; NR4A2; CHD7; MEOX1; RBPMS; ZFPM2; KDM5D; ZNF274; HEY1; ZNF217; MSX1; PBX1; TRIP6; CITED2; IFI16; ZBTB16; TOX3; EGR1; CEBPA; NFKB2