Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68600	Zaprinast	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	128	MEF2C; SMAD3; THAP11; BCL10; BRD7; SIAH2; PRDM2; SPDEF; TAF4B; PRMT2; ZNF532; TERF2; ZNF282; ZNF816; CBX2; NSD1; CREM; SHOX; ZNF117; HMGA1; ZNF253; ETV4; ATN1; ZNF467; TRIB3; ZNF195; KLF3; PRDM14; HIC2; SSBP3; ECD; ZNF688; DAXX; NEUROD6; ZNF33B; ZNF124; FOXK2; RARB; STAT4; AATF; ZNF423; PCGF2; TAF9; POU5F1B; ARID5B; PRDM1; FOXG1; RNF138; CTNNB1; AR; LIN28A; ZHX2; NFYA; MNDA; CDK9; TAF5L; TCF7L1; URI1; NR0B1; CBX4; LMCD1; TEAD4; KDM4C; IRF6; CEBPD; ERF; NR4A2; TFAP2A; E2F5; SP140; SPIB; LOXL2; GTF2I; MXD3; MKL2; TRIM16; ZNF665; NEUROG1; POU2AF1; CCNE1; INSR; SOX11; SHOX2; IL16; FOXA1; GRHL2; POU4F1; TFAP2C; EGR1; PGR; ZNF43; SMAD1; ZNF589; DBP; ZNF394; ZNF652; ZNF165; CREBL2; ZNF232; NANOG; MNT; YAP1; MYRF; HBP1; JUNB; KLF11; FOSB; HDAC9; COPS2; SOX17; KLF4; TCEA2; ZFP36L2; TBL1XR1; CBFB; LITAF; MEIS2; BCL3; NR2F1; BCL11A; GATA6; TRIP6; MECOM; HOXB7; ERBB4; CDK7; DNMT1; CRK
Down-regulation	144	GTF2A2; DRAP1; RBL1; BRD8; RRN3; ASCL1; SAFB2; NCOR2; PSMC3IP; ING3; TBP; UBE3A; BCOR; ARNT; ZNF587; HMGA2; SREBF2; FHL2; PAWR; PTRF; RNF111; FLNA; DPF2; HCFC2; MITF; ZNF329; EDF1; PPARGC1A; LPIN2; RBM14; KAT5; L3MBTL1; TLE1; MEOX2; HDAC6; HNRNPD; SAP18; EP400; ZNF551; PHF8; NR2C1; TGFB1I1; RUVBL2; ZKSCAN7; HMG20B; CITED2; TAF5; RLF; ENO1; GFI1B; SMARCE1; ZBTB20; RELA; ID4; PBRM1; NOC2L; BATF3; NCOA1; ZNF410; NR2F2; FHL5; EP300; PITX2; NFYB; BMI1; SALL1; SND1; SMAD4; STAT6; NFIB; MAF; HMGB1; NEDD8; ZNF426; HOXB13; RAD21; CTR9; BTG1; BCLAF1; PBX3; MED24; MYCN; TMF1; REST; CRY1; LEF1; WIZ; IRF1; ZSCAN18; GATAD2A; MYB; ING2; ZMYND8; INSM1; JARID2; ZNF302; ZNF266; YEATS4; SOX10; TAL1; PLAGL1; EED; ATF3; ATF4; YBX3; MEF2A; ACTL6A; TCF12; MAFF; ALX1; ZBTB38; ZNF131; CUX1; BASP1; NFKB1; SMAD6; ZFP36L1; PITX1; PURA; ISL1; WWTR1; BRD2; NUP62; MAFB; SSBP2; TOX3; TLE4; IRX5; KAT2B; ZNF83; KLF10; MLXIP; TSC22D1; ZKSCAN1; HTATIP2; ZNF274; DLX2; ZNF217; WT1; HOXB2; MNAT1; EMX2; ZBTB16; CEBPA