Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68591	L-701252	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	367	PPARG; PAX8; IKZF1; GATA3; RFX5; SATB1; SMARCD2; ARID4B; FOSL1; MYBL2; ELF1; OVOL2; KLF10; RBL1; ZNF556; AFF1; EGR4; TXNIP; ZNF672; FOXJ1; KLF2; STAT5A; ZNF669; NFE2; NCOA4; FOXO4; NPAT; RUNX3; ARNTL2; EHF; EPAS1; PDLIM1; TFDP1; RNF141; RHOA; ZNF165; GFI1; NR0B1; ZNF226; ETS2; CIITA; ATF1; KDM5A; HOXA10; HLTF; YEATS2; VGLL1; SMARCA2; BRWD1; SHOX; TAL1; ZNF652; ELF4; STAT5B; TSC22D3; RB1; SIAH2; HNF1B; SNAI1; NR2F6; ZBTB25; GATA4; TULP4; ZHX3; TRIP11; CCNE1; RARB; SREBF2; TRIM22; ZNF217; BBX; HOXC8; HNF4A; NR2C2; HLF; WHSC1L1; KDM5D; KLF4; STAT3; ELF3; SIX6; TTF2; MYBL1; CD3D; HOXC10; TERF2; CHD3; PBXIP1; PPARA; TFEC; CHAF1B; ARID5B; BCL11B; MNX1; ZBTB40; E2F8; HES1; SMAD5; FOXO3; PPARD; NFATC1; PRDM13; ZFY; NFAT5; MED12; BCL10; TBX19; BCL11A; SPDEF; PAX5; ACTL6A; TCF7; MKL2; ZNF813; ZKSCAN1; PHF8; VDR; CBX7; AEBP1; BACH1; MYT1L; NEUROG2; ASH1L; IKZF2; ZNF770; MTF1; SIX3; PHOX2A; TFAP4; FHL2; NFX1; TAF1; MYNN; BIRC2; HTATIP2; EN1; NAB2; ZNF467; ZSCAN31; WWC1; POU3F1; RELB; ID1; FOXA2; PROP1; ETV6; EP300; ANKRD1; WWP1; PIR; ZNF764; ZNF587; STAT6; EYA2; TSC22D1; MAK; HIPK1; MYC; HOXA6; PRDM5; PAX1; HOXD3; ZNF692; ARRB1; TBX21; DLX4; ARID3A; DEK; HOXC13; OVOL1; GATA6; RBL2; EGR3; TEF; TBL1X; TOB1; POU4F1; ZNF701; ACTL6B; SKIL; ZNF324B; ZNF639; PRDM1; CSDE1; NFE2L2; HDAC4; TAF1D; NOCT; NR3C2; BCOR; MYCL; TBX5; KLF6; NFRKB; KDM2A; TRIM16; RFX2; E2F3; CBFA2T3; TWIST1; PLAGL2; TEAD1; ZBTB38; LHX6; ZNF783; HHEX; CALCOCO1; AIRE; FOXC1; LYL1; JUP; BNC1; HLX; HDAC11; MAFF; NKX3-2; NKX2-5; MLXIP; TBP; HOXA7; FOXK2; SCMH1; TFAP2B; MECOM; PNRC1; TCF20; SETD3; PRDM8; NEDD8; ERG; ZSCAN16; TFDP2; GRHL2; SIX1; SSBP3; FOXD1; WT1; ERBB4; MECP2; TRAF6; EZH1; HOXC4; PIAS1; PEG3; JUNB; FEV; HMG20A; FOXH1; YWHAB; UIMC1; MDM2; OSR2; ZNF117; ZBTB44; SERTAD2; KDM4C; FOXG1; ZNF665; CDK9; ZNF410; EBF2; ZNF266; FOXI1; KLF7; RELA; NR1I3; PAWR; ID2; LITAF; ZBED2; SP140; ZNF629; PROX1; RNF111; NR4A3; RARG; KLF9; MED7; ATF7IP; PRMT2; FOXE1; ASH2L; ONECUT2; FOXF1; SOX10; NKX3-1; MYB; HOXA1; DMRT1; RORC; TRIM29; SNAI2; SOX17; ETV1; CREM; REL; BHLHE40; PIAS3; YBX2; VPS72; RBBP7; NFKB1; NFE2L3; TRAK1; PSMC3IP; ZMYM2; LEF1; SIM2; ASXL1; TFCP2L1; GTF2I; EGR2; TBX3; KLF3; ASCL1; IRF1; JUN; YEATS4; HIVEP2; MYRF; PRRX1; INSM1; HDAC5; PITX1; NFKBIB; TRRAP; TRPS1; ZNF654; IRF4; KLF1; HDAC1; CREBL2; RORA; MAML1; SMAD6; NR1D2; TFAP2C; TCF21; NR4A1; MEN1; ZBED1; EMX2; SMAD2; MNDA; DNMT3B; HDAC9; MED1; WWTR1; VEZF1; FOSL2; FOSB; CUX1; RUNX1; CTR9; ZSCAN18; BATF; NUP62; NFKB2; ZNF721; EED; SOX9; MEIS2; ZBTB18; ZNF160; HOXC6; ST18; CDK7
Down-regulation	463	USP22; PSMD9; PUF60; CCNA2; KAT6B; PSIP1; NCOR2; GMNN; CHD9; ARID1A; HIRA; ZNF140; SMARCC2; PA2G4; ZNF268; GABPB1; MED16; RAN; C1QBP; TCEA1; TRIB3; NCOR1; APEX1; INSR; PTTG1; ZNF432; SOX2; CARHSP1; GATAD2A; ABL1; BTF3; ARID5A; PIAS4; SMARCC1; BRD8; ZNF32; ZNF232; PRDM10; SOX4; TULP3; ATF2; ELF2; CCDC59; BRD7; RUVBL1; RNF4; BAZ2B; ZNF10; RING1; ZNF444; CERS6; HOXD11; MED21; KAT6A; RCOR1; SIRT2; CTCF; UBE3A; ZNF84; ZNF43; BRD2; CDC5L; PQBP1; DNAJC2; ZNF593; MTA1; GMEB1; SP110; CHD8; IRF9; MED24; SALL2; BAZ2A; TLE1; SALL1; ABT1; TCF3; LZTR1; SFPQ; MED27; ZNF22; CXXC1; TRIM28; BRF2; TDP2; ATF4; ZNF146; NELFB; TERF1; ZNF195; POU3F2; ZBTB11; SUV39H1; TAF9; HMGN3; CBX5; ETV5; CCNC; TCERG1; MKL1; PBRM1; TRIM27; ZNF329; NR2C1; THAP10; SP140L; HMGB3; GLI2; ZNF668; RNF10; KMT5A; HSF2; GTF2F1; RYBP; TDRD3; BRD4; TCF7L1; SPEN; ZNF131; RUVBL2; ZNF358; SUB1; MED13; THAP7; LOXL2; TLE2; PHF1; PCGF1; RAD21; SOX11; HCFC2; DNAJC1; JARID2; DR1; AFF2; SCAND1; CCNT1; ATN1; SREBF1; ZNF281; FOXJ3; ZNF423; DAXX; DACH1; HNRNPD; APBB1; HMGA2; PMS1; SUPT3H; ETV4; CITED1; ZNF580; HMGXB4; ZNF263; SMAD4; ENO1; ZNF688; UBE2I; SUPT5H; CIZ1; CBX4; SMARCB1; MTF2; AES; MED17; ZFHX3; TAF5; SAP130; PREB; RERE; RBM14; ZNF12; TGS1; ZNF574; HMGA1; ZBTB7A; UBTF; HOXA11; ZEB2; ZNF711; HOXD1; ZEB1; SOX15; ZNF254; HIC2; ERCC2; CBX3; MBD3; ZSCAN9; CARM1; MED4; MDM4; REXO4; ZFPM2; BCL6; HDAC2; ZNF536; RNF138; HSF1; NRIP1; ZNF606; LDB1; IRF8; RFC1; FOXA1; CTBP1; KLF5; ZNF112; E4F1; YBX3; ZNF551; ZNF835; ZNF219; ITGB3BP; SMAD1; RBFOX2; ZFP37; THAP1; CERS4; ZNF174; NOC2L; NR2F2; ZNF586; ZNF771; ERBB2; MDFI; NFIB; PPRC1; PBX3; RBBP8; BACH2; ZNF222; ZNF419; RBBP5; RBM39; MTDH; PKNOX1; SMAD7; ZNF85; CNOT3; NFYC; MGA; COPS2; PEX2; ZNF302; UBE2L3; ZNF212; MAZ; TGFB1I1; ZMIZ1; TAF11; SOX13; PITX2; ZNF74; CBFB; HIVEP3; IRF7; CNOT2; XRCC6; ZNF45; PATZ1; HMG20B; SMARCD3; PIAS2; ID4; ZNF180; ZNF133; SNIP1; HCFC1; PFDN5; DEAF1; RLF; SRCAP; YAF2; NR2F1; CEBPZ; PRKDC; CLOCK; ZFP30; ZNF34; CTBP2; HIF3A; ZBED4; MED15; RBPJ; NPM1; SMARCE1; CREB5; GLI3; PSPC1; STAT1; ZNF136; NR1H2; ZFHX2; ATF5; MSX1; DMTF1; SIX2; CUX2; ZNF562; ZNF143; ZNF44; CSDC2; EWSR1; SUMO1; HIF1A; SAP18; RFXANK; HOXD13; ZNF189; CRY1; ZBTB14; FOS; ZBTB17; MED20; CENPB; ZNF345; WIZ; GTF3A; MED25; THAP4; GMEB2; HOXB6; POLR2A; MYOG; REST; ZNF134; HEY2; MEOX2; MED23; ZNF184; ING3; TFAM; MED14; FOXM1; POU2AF1; TEAD3; BPTF; SUPT7L; SPI1; KAT2A; ZNF667; SMARCA5; TAF6; ZNF304; BASP1; POU4F2; PMF1; SF1; KDM4A; BCLAF1; SATB2; EDF1; TAF5L; PEX14; UTF1; SMAD3; MNT; ZNF273; ZNF177; ZNF516; ZNF512B; E2F5; ING1; ZSCAN32; PAX6; GON4L; SUPT6H; SAFB; MLLT10; MAX; HDAC3; NFIC; NRF1; FOXO1; CREG1; ZNF430; LPIN2; NKX2-1; TCF25; HAND1; PHIP; MBD2; HMGXB3; ZIC1; DRAP1; ELK3; ENY2; NFYA; SAP30; ARNT2; WHSC1; TCEA2; HOXB5; CEBPB; TAF9B; ZIC3; SUPT4H1; BRD3; ZNF83; ZHX2; BNC2; HMBOX1; ZNF623; NR1H3; HEY1; CREB1; TLE4; HMGB1; KAT8; CHD7; SIN3B; ZNF107; MMS19; SMARCA4; TGFB1; PBX1; CDK8; MAF; CAMTA1; RNF14; ZNF14; DPF2; ZFP36L1; FOXN3; PHF20; MNAT1; ZBTB16; IKBKAP; BATF3; CNBP; CHD1; ZFX; ZNF124; ZNF91; ZMYND8; TRIP6; YBX1; DDIT3; ZBTB20; CRK; NANOG; TOX3; CALR; GTF2IRD1; TCF12; CITED2; PCGF2; MAGED1; ZNF573; MAFB; MEIS1; TGIF1; SSBP2; ETS1; ADRB2; EGR1; IRF6; ZNF589; SLC2A4RG; BHLHE41; ZFP36L2; CEBPA