Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68587	Mibefradil	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	325	HIPK1; IRF9; LZTR1; ZNF331; THAP11; NKRF; CCNH; PRDM14; KDM5A; ATN1; PRDM2; TFAP2A; ELF4; CEBPD; MYBL1; ZIM2; EN1; SPDEF; JUN; ZKSCAN3; NEUROD6; AR; SSBP3; MYBL2; TDRD3; VPS72; SMAD3; E2F8; IRF6; TRPS1; LHX3; TAF1; ARID1A; ZNF467; GATA6; TAF5L; CREM; LMCD1; BCL11A; CBX2; ZNF354A; THRB; RARG; HLX; MED15; TAF4B; TERF2; TULP3; EMX1; MXI1; ZKSCAN4; ZNF235; FOXJ1; PROP1; ZBTB25; VGLL1; PCGF1; NEUROD2; ZNF141; ZNF816; KDM5C; TFAP2C; ZNF75D; POLR3C; MED12; PAWR; ASH1L; ZFHX3; ZNF85; HIPK2; ZNF665; FOXJ2; AEBP1; ARID5B; CDIP1; TP73; NFATC3; GATA2; CAMTA2; CBX4; TTF2; ZNF701; BAZ2A; TAF1C; ZNF74; CALCOCO1; ZNF688; E2F4; SRCAP; ZNF580; MBD1; CHD2; ZNF264; HOXC10; CBX6; ZNF93; ZBTB44; HMBOX1; PRMT2; ZNF556; TRIB3; KDM4C; ZNF345; ERG; SNAI1; BNC1; BNC2; ZNF444; ZNF682; NFATC1; ZNF33B; KLF9; ECD; ALX4; POU5F1B; CERS6; ZNF124; PPP1R13L; ZIC3; CSDC2; ZXDC; TAF4; ZHX2; TUB; YEATS2; SERTAD2; ZNF215; CNOT3; TRIP11; PHF1; SETDB1; RAD21; BRWD1; ZNF180; BCL11B; SSX7; ZNF253; PAX6; TOB1; SOX13; NR0B2; KLF3; KLF6; SPIB; ZNF232; SNAI2; CSDE1; TCF7L2; ZNF652; SPI1; ZNF500; TGIF2; ZNF239; CDX1; ZNF586; MNDA; ZNF117; ZNF43; ERBB4; NCOA2; TSC22D3; NFRKB; SSBP2; ZNF623; MKL2; CREB3; HHEX; SRY; DLX5; SOX18; JUNB; RFXANK; TDP2; PEX14; NR5A2; PBXIP1; NFE2L3; CREBL2; CCNT1; BARX2; PRPF6; MBD2; HOXC8; OVOL2; ACTL6A; KLF15; SOX17; CREB3L2; ESRRG; FOXE1; DBP; WNT4; VDR; TAF9; ARNTL; HBP1; IRF7; GON4L; MED25; NFAT5; HOXC4; GRHL2; ZNF350; ZSCAN32; SAP30; CALR; CIR1; ERF; TEAD4; SNAPC4; IRF3; MTDH; PBX3; CDK2; ZNF430; NR4A3; ZNF394; GATA4; ESR1; PSMC3; BHLHE41; DLX2; CEBPB; PNRC1; USP21; ATF3; GFI1; CBFA2T3; FOXF2; YAP1; HTATIP2; RING1; MLLT10; NFYA; EPAS1; SHOX2; TCF7; OSR2; BPTF; CCNE1; SUPT6H; DAXX; INSR; FOXN3; TAF6; TBX3; NFE2L2; TGFB1; AES; HDAC9; RUNX1; AGO2; FOXI1; SOHLH2; SMARCA2; ZNF200; LITAF; CD3D; SUPT5H; FOSB; NFE2; LHX6; ZNF426; MITF; SLC2A4RG; NFATC4; CBX7; BRD4; MAML1; HOXB5; TCEA1; KLF13; ZNF136; HSF1; RBL2; MYCL; NR0B1; SSX1; TCEA2; URI1; EHF; ZNF165; CREB1; RUNX3; KLF11; SOX9; NR1H3; ZFP36L2; MYRF; SATB2; ZNF654; MNT; JUP; HOXB6; PGR; RREB1; NANOG; AHR; ETS1; NR3C2; NR1D2; TGIF1; ZNF589; ELF5; ZNF107; ZNF91; IL16; FOXA2; ZBED2; FOS; DNMT1; TRIM24; SMARCA1; WT1; TP63; ST18; KAT2B; ID2; BTG1; ZBTB16; ELF3; MEIS2; TWIST1; LEF1; HOXB7
Down-regulation	282	HDAC2; HMGA2; CCNA2; TCERG1; HNRNPD; SMARCC1; MED24; RAN; PSIP1; USP22; SNW1; RBM14; PUF60; RBBP4; SOX2; TBP; EDF1; RHOA; HSF2; MED16; SMARCE1; HDAC6; KAT5; RNF4; MED23; KAT7; GABPB1; YBX1; PARP1; SOX11; ATF1; MED4; CCNC; DRAP1; ZNF329; TRIM28; BRD8; BASP1; PMF1; DDX5; NRIP1; CEBPZ; NPM1; SIX2; NEDD8; PHF8; HMG20A; BTF3; SALL1; BRD3; BRCA1; NONO; KDM5B; PHF2; BCLAF1; STAT5B; HMGN3; THAP1; SUB1; SNIP1; TSC22D2; ARID4B; BMI1; SP2; NELFB; LZTS1; EP400; PSMC3IP; ZKSCAN7; YWHAB; C1QBP; PBRM1; ZNF672; ENO1; RUVBL2; KAT6A; SUPT4H1; SMARCD3; HDAC1; BATF3; FOXO3; MAGED1; SIX1; NCOA4; ETV5; FOXJ3; JARID2; RNF141; NR2F2; TAF11; SREBF1; ZBTB24; UBE2I; USF2; TBPL1; BAZ2B; ELK1; SMARCA5; PRKDC; TADA2A; SFPQ; RCOR1; TRIM32; TRRAP; ABT1; PCGF2; RBM39; MDFI; NRBF2; ZNF764; EZH2; CITED1; ZNF292; ZNF410; EYA1; PPARGC1A; ZNF587; HSBP1; ZBED4; ZNF212; SMAD4; NFKBIA; ADNP2; HMGB3; NUP62; PATZ1; MEOX2; CHD7; UBE2L3; SUV39H1; PCBD1; ETV4; NACA; APEX1; ABL1; TCF15; DDX54; CTBP1; RBBP5; ETV1; TAF1D; DNMT3B; EWSR1; NFYC; PBX2; ZNF23; RBPJ; NR2F1; CBFB; ZNF787; KDM5D; CBX3; HMGB1; KDM2A; LPIN2; BAZ1B; PQBP1; SUPT7L; ID4; TSC22D4; CDK8; TOX; GABPA; SAFB2; RBL1; TLE4; NFIL3; PITX2; MED1; DEAF1; ZNF783; EGR2; RERE; NCOR2; CDK9; MYT1L; DPF2; RNF10; ZBTB11; TCF4; ZNF84; ORC2; ERCC2; ZNF226; TLE1; NKX2-2; CDK7; TBL1XR1; PIAS2; CRY1; HLTF; NLK; SP140L; ZNF76; CTR9; TP53; UBE3A; MYCBP; SMARCA4; ITGB3BP; MDM4; BIRC2; ZEB2; HDAC3; REST; MAF; PITX1; EED; AATF; CBX5; ZNF148; GATAD2A; GTF2IRD1; TOX3; SND1; RBBP7; REPIN1; ARRB1; CARHSP1; YAF2; WWTR1; TAF7; SMAD2; KMT5A; ZNF532; OLIG2; MMS19; TFAM; NAB1; BRPF1; DR1; IKBKAP; WHSC1; ERBB2; ASCL1; SP3; ATF4; SCAND1; PREB; PTTG1; YBX3; TCF12; VGLL4; PSPC1; ZIC1; DDIT3; TGFB1I1; E2F6; DNAJC1; TRIP6; ZNF189; NFE2L1; TAF10; ZFHX4; CREB3L1; ZNF22; XRCC6; BRD2; PLAGL1; MED6; IRF8; ISL1; ZNF248; ZEB1; EGR3; EMX2; STAT3; INSM1; VEZF1; MSX1; ZNF274; ZSCAN18; HMG20B; FOXD1; ZMYND8; ZBTB20; BAZ1A; DMTF1; MECOM; HMGB2; HOXA5; CEBPA