Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68521	Chlorthalidone	GSE92742	NPC	Human	24h	10uM	EID0374

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	RELB; STAT5B; BRCA1; CEBPZ; ZNF331; CREB3; CREM; CARM1; SPI1; EGR4; TDP2; BCL3; HLX; SMARCB1; IRF9; DR1; BHLHE40; POLR3C; HLF; NR4A3; TFAP2A; TP63; NR1H3; VPS72; C1QBP; NFKB1; EMX2; NANOG; SOX13; SNAI2; BNC2; KLF3; CNOT3; PCGF3; GLI2; NAB1; NUP62; ZBTB38; BAZ1B; FOSL2; SMAD1; IRF1; APEX1; DDX17; RBPMS; MYBL1; ID1; KLF4; ESR1; TGFB1; TGIF2; TRIM29; HLTF; KLF5; ZNF589; RORA; DACH1; REL; MKL2; MNAT1; POU4F1; TFDP2; RBBP8; NFKB2; HIPK3; ZHX2; JUNB; CITED2; BHLHE41; NKX2-1; TCEA2; KLF9; ZBED2; PBX1; ETS1; PEG3; MYCBP; HOXB2; SOX9; WT1; CRK
Down-regulation	88	TLE1; TRIB3; CDK9; TSC22D4; SIM2; RCOR1; NKX2-2; NCOR2; BRD3; ZSCAN32; SOX4; ZBTB43; ZNF669; ZBTB11; HOXC6; ZNF184; CIZ1; LEF1; HIRA; BTG1; MYT1; CARHSP1; CHAF1B; SOX10; ZSCAN16; BRPF1; POU2AF1; IRF4; BRD8; ZNF652; ZMIZ2; EZH2; MED27; ZNF211; CTBP2; ZNF84; HTATIP2; ZNF692; MAGED1; AFF1; NFATC1; OLIG2; ZNF536; KLF2; MAFG; BLM; GATAD2A; MEN1; ZEB2; POLR2A; ASCL1; IRX5; BRD2; CRY1; REPIN1; PHOX2B; NR2F2; HOXC10; ZNF468; MBD4; ATF4; ZBTB18; NFE2L1; ALX1; TOX3; ZFHX4; HEY2; ERBB2; MLXIP; PTTG1; GRHL2; ZNF107; SAP30; KLF10; ZKSCAN1; TRIM24; TBL1XR1; ZNF91; PCGF2; MED1; ID2; EGR3; PBX3; ZFP36L2; LITAF; ZBTB16; EGR1; CEBPA