Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68479	Mdm2-inhibitor	GSE92742	NPC	Human	24h	10uM	EID0373

Response Information :

Types	Number	Response transcription factors
Up-regulation	63	JUN; KLF4; CERS6; TCEB2; DACH1; ZNF516; PGR; TULP4; AR; MNDA; CSDE1; TCF21; PAWR; ST18; TFAP2A; BTG1; IRF6; HTATIP2; BACH2; WNT4; NCOA2; FOSB; LOXL2; OSR2; FOXA2; BAZ2B; ERBB2; IRF9; TBX3; ZNF532; MYB; REL; EHF; TRIM16; TLE4; INSM1; BCL11A; PCGF2; MEIS1; DDX17; TXNIP; WT1; ZSCAN31; NFATC1; IRF8; ZNF652; CBFA2T3; HOXC6; MYRF; SNAI2; APEX1; ARNT2; BASP1; EGR1; PBX1; LEF1; TFEC; BHLHE41; ZBED2; ESR1; PBX3; EGR2; MEIS2
Down-regulation	91	NFIB; ZNF44; ZNF443; ING3; CRY1; ZNF148; LPIN2; ZBTB11; ZBTB1; DEK; SLC2A4RG; BCL3; HNRNPD; BRD4; FLNA; TEAD4; EED; IRF5; NCOA4; PPARGC1A; ZNF529; NR1D2; MECOM; ZBTB43; BBX; ZBTB38; ZNF813; MEF2A; YEATS2; TEAD1; MLX; FOSL2; ZNF329; VEZF1; DNAJC2; KLF2; ZNF14; TFCP2L1; ZNF266; HLTF; ELK3; CREB1; IRF4; ZNF134; ID1; STAT4; DDIT3; ZNF331; ARNTL2; NFYB; DNMT3B; RBBP8; STAT3; PRRX2; TRIM22; KAT6B; CD3D; NFIC; HLF; CCNE1; ZNF512B; HMGB2; MED21; ZNF562; MAGED1; CBFB; XBP1; SIX2; KDM5D; SMAD1; PIR; FOXC1; WWTR1; ZNF468; TCF4; RORA; NRIP1; EYA2; CDK7; YWHAB; NR2F1; TAF10; ZSCAN18; MYC; AFF1; SOX10; ERBB4; TCEA2; ATF1; TOB1; USP22