Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68470	Leflunomide	GSE92742	NPC	Human	24h	10uM	EID0373

Response Information :

Types	Number	Response transcription factors
Up-regulation	58	NFE2L2; TEAD4; ZNF217; LDB1; TULP3; ELF4; TFAP2A; TCF21; IRF6; WT1; ST18; GATA6; ZNF180; CCNH; SNAI2; VPS72; AHR; TRIB3; MAGED1; JUND; GTF2IRD1; BHLHE41; CEBPD; BNC2; PCGF3; IRF9; MED17; OSR2; YAP1; ZNF467; MYBL1; ETS2; OVOL2; HOXC10; ZBTB20; ARID5B; ZFPM2; ZNF331; ERBB4; VDR; HOXD1; JUP; HOXD3; HOXB2; TOX; SMAD7; ID1; SMAD1; ZBED2; TCEA2; MEIS2; NR4A2; KLF5; ZFP36L2; PBX3; ID3; YBX3; EGR2
Down-regulation	75	BMI1; MSX1; PSPC1; HLTF; BCL11B; TSC22D3; RBBP4; FLNA; MEF2A; HIPK3; KDM2A; DNMT3B; RNF10; HDAC4; TCF12; CTR9; ZMIZ2; DNAJC1; ID2; VGLL4; TSC22D2; MYCBP; RBBP5; TCF4; WWTR1; EDF1; BTG1; SMARCA2; BAZ1A; BRD2; RBBP7; XBP1; ZEB2; NELFB; SCAND1; SATB2; ZNF432; BRPF1; KAT6B; TBL1XR1; NKX2-2; ARID4A; PAX6; SALL1; UBP1; FOXG1; BAZ2B; AFF1; TBL1X; NR2F2; TFAM; TRIP6; SMARCA1; FOXJ3; NRIP1; C1QBP; HSBP1; TGFB1I1; EYA2; ELK3; RBPMS; POU4F1; HTATIP2; BASP1; MAF; MYB; ZBTB18; CRK; PBX1; TAF10; BCL11A; KDM5D; MAFB; ZIC1; EGR1