Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID68346	Midostaurin	GSE92742	NPC	Human	24h	10uM	EID0373

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	JUN; NFATC4; ID2; CCNH; DLX2; RARG; ZMYND8; ZNF573; PDLIM1; CBX4; PRDM2; AIP; EN1; CBFA2T2; TFAP2A; PAWR; TSC22D3; ZNF215; TULP3; ST18; HOXC13; VGLL1; SRCAP; ZNF580; SP140L; IRF9; HHEX; ZNF444; CEBPD; RBM39; ELF4; HOXC11; CEBPG; HDAC9; IRF7; SPIB; HOXB1; ID1; ZNF24; SP110; INSM1; NCOA2; PCGF3; FOXF2; BPTF; VPS72; RAD21; FOXA2; ZHX2; JUP; LZTR1; ARID5B; BACH2; PCGF1; PNRC1; SERTAD2; MYRF; SIRT2; GATA6; AHR; ZNF264; JUND; BCL11A; BHLHE41; CBFA2T3; CEBPB; ID3; ZNF589; GTF3A; ZBED2; TOX; FOXE1; MKL2; ZSCAN31; RUNX1; PEG3; ZBTB20; SNAI2; TRIB3; ATF4; ESR1; ZFP36L2; FOXG1; ARNT2; DLX5; CERS4; TGFB1; HOXC10; ZNF91; EMX2; KLF11; TRIM16; WT1; POU2AF1; MYBL1; ERBB4; ATF3; TOB1; LITAF
Down-regulation	181	HMGA2; ZNF443; PSIP1; RCOR3; BMI1; HES1; RUVBL2; MAML1; ZNF614; PIAS3; BRCA1; FOSL1; RFX7; DNMT3B; ING1; EED; CENPF; GABPA; NPAT; PHF8; TRRAP; ORC2; SSRP1; PARP1; ING3; RBPMS; DDX54; STAT5B; SMARCA5; KDM5A; CIZ1; NUP62; TBPL1; MSX1; ZNF672; MTF1; HNRNPD; PATZ1; ZBTB18; SP3; BRD3; SAP18; AATF; ZBTB38; ARID4A; ZNF432; SMARCE1; POLR2A; RBBP4; SMAD5; ETS2; TRIM28; SLC2A4RG; HLTF; ZMIZ2; NCOA4; AFF1; SUV39H1; ECD; CTR9; SNW1; YBX1; MED7; ADNP2; BBX; FOXN3; ZEB2; ZNF226; HMGB3; SFMBT1; RLF; PSMC3IP; CREBZF; FLNA; PIAS2; TP53; ETV1; DNAJC1; TRIM32; MAF; MDM2; HEY2; ZNF329; AGO2; SAP30; CBX3; SIAH2; PPARGC1A; MYCBP; ASH2L; RBM14; ZNF813; RNF14; ING2; RBBP7; NR4A1; NFAT5; SFPQ; ZNF468; TMF1; BAZ1A; TCF12; HMGA1; NAB1; NCOR2; EYA1; MEF2A; PCGF2; KLF1; XBP1; CRY1; SUB1; UBP1; ZBTB43; ZNF200; LPIN2; BAZ1B; SMAD4; ISL1; RNF141; EGR4; ZNF22; DEAF1; KLF2; BCL10; FOXF1; VEZF1; NKX2-2; NR2F2; ZNF267; EHF; CDK7; RCOR1; HMGB1; EGR3; BLM; MNT; ENO1; MITF; MAGED1; MEIS1; SALL1; RBBP8; TFAM; EDF1; WWTR1; CEBPZ; TGFB1I1; MYT1L; SMARCA2; PITX1; CBFB; TCEA2; ELK3; STAT3; TAF1D; CBX5; TBL1X; HEY1; ZNF160; FOXJ3; TFDP1; CITED2; PIR; MYCN; CREB3L1; FOSL2; TSC22D2; ATF1; CRK; HLF; NFKBIB; NKX3-1; NRIP1; HMGB2; USP22; EGR1; ASCL1; NFIL3; BASP1; EGR2