Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID67713	Leflunomide	GSE92742	ASC	Human	24h	10uM	EID0370

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	NKX2-2; SUPT4H1; JUN; HSF1; ST18; NAB2; IRF5; HIPK2; ZKSCAN4; PRDM14; PARP1; ARL2BP; FOXF1; MKL1; HMX1; ZFP36L2; SCAND1; CARHSP1; RBPJL; ZNF257; TULP3; SAFB; NOC2L; BARX1; ZNF350; HOXD13; SALL1; MYRF; SALL2; ZNF331; FOXO3; SMARCC2; ZNF224; ZSCAN9; PBX1; FLNA; ZNF671; ZNF345; BNC1; ZNF500; BRWD1; FOXL2; ZBTB16; NR2F2; BNC2; CXXC1; IRF4; HIRA; ZNF264; KMT2B; DDX17; PRPF6; IRF9; ZBED2; ZNF426; SMARCA1; PEG3; TCF21; CREB3L2; TCEB2; CHD4; CBX4; RXRA; CCNE1; KLF11; PNRC1; CERS4; NR4A1; SUPT6H; MEIS2; DNMT1; FOXE1; SOX11; BHLHE41; NFKBIA; MED13; WT1; ZNF711; JUP; ADNP2; ID4; TDP2; MNDA; SATB2; FOXF2; SMARCB1; KLF7; NKX2-1; ELF4; ZNF551; SOX9; PBXIP1; NR4A2; GRHL2; ZNF93; GMNN; CNOT3; EYA1; YAP1; FOXM1; NR1H2; NR1H4; TLE4; DDX5; CALR; PBX3; HES1; GATA6; ZNF611; ABL1; MAF; ARNTL2; HHEX; MBD2; TFAP2A; SMAD3; ZFP36L1; ID1; CREM; HMGA1; NR2F1; TCEA2; ZNF91; ARNT2
Down-regulation	171	NR2F6; TSC22D3; TLE1; NFIB; HOXB7; TSG101; MSX1; RNF10; FOXJ3; XBP1; NR2C1; ZZZ3; TFE3; BATF3; PSMD9; ZBTB25; RNF14; FHL2; SIX1; C1D; STAT6; STAT1; CDK8; ZBTB18; HOXC6; HDAC6; ITGB3BP; MED20; ZNF143; ING2; TRIP6; MYC; KLF2; NFYB; ZMYM2; ZMYND8; REST; THAP1; SIN3B; TRIM22; ZNF267; VDR; YWHAB; BMI1; HLTF; EGR3; IRF8; NUP62; PPARG; STAT5A; SAP30; MED7; ZFP64; IRF7; CCNC; CRK; ZNF107; CTR9; PIAS3; TAF10; ATF2; GTF3A; LEF1; MNAT1; RBM14; MTDH; NFE2L1; CRYM; SMAD7; SP3; UBP1; CCDC59; BBX; PATZ1; SOX4; ECD; BCL10; RNF6; SERTAD2; SMARCD3; STAT3; KLF10; ZNF14; HOXC10; ZNF217; ZNF226; PPP1R13L; ZNF146; RELA; TSC22D1; HIVEP2; PHF20; KAT6A; MED21; ZNF443; SMAD2; CHD1; NKX3-1; NCOR2; RBBP8; TBL1X; MEOX2; BAZ1A; BCLAF1; TERF2; SIAH2; HTATIP2; NCOA4; MEN1; TGS1; RREB1; EMX2; HOXB2; HOXB6; ZMIZ2; REPIN1; TADA3; EZH2; MED6; ZBTB11; PMS1; ZSCAN18; RUNX1; ELF5; TFCP2L1; IKBKAP; EYA2; E2F5; BHLHE40; ASH2L; PIR; LIMD1; ZBTB1; CREBL2; TMF1; TBL1XR1; SP100; SMAD1; SSBP2; NCOA1; ASCL1; EHF; HOXA10; MYB; NR1H3; EGR2; ZKSCAN1; ZNF468; ESR1; CBX3; NFAT5; ATF1; IRX5; KDM5D; ARID4B; FOSB; ERG; PCGF2; ATF7IP; CITED1; ELK3; RFX5; TRIM16; FOXC1; SFPQ; TRIM32; USP22; NRIP1; HDAC9; TGIF1; NR3C1