Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID67682	Icariin	GSE92742	ASC	Human	24h	10uM	EID0370

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	KDM5A; ZFP36L2; IRF6; ATOH1; MXI1; NKX2-2; ID1; UBE2I; TDP2; TFDP2; PSMC3; CDX1; TBX3; SPDEF; TCEB2; RXRG; CHD4; CHD8; KDM5C; ID4; ATN1; JUN; NFE2; TCF21; CTCF; SCAND1; ARID1A; GRHL2; GATA6; ZNF500; PRDM10; DDX17; PRDM1; PFDN5; HLX; PBX3; CNOT3; RARG; GATA1; KLF1; ZNF219; HAND1; HIRA; MEIS1; EYA1; MKL1; CUX2; SALL1; SSBP3; ZNF331; TCF7L2; EN1; SIX3; PGR; ZNF467; MYCN; FOXM1; CBX4; TRPS1; CDK2; ZBTB16; DACH1; TFEC; PAWR; MED14; HHEX; TFAP2A; MYRF; PEG3; LITAF; BCL11A; GATA2; HMGB3; HOXB5; EPAS1; CALR; EHMT2; FOXF2; RAD21; PBX1; WT1; CREB3L2; MEIS2; BANP; FOXF1; NR4A3; BTG1; SATB1; GMNN; ARNT2; MYB; ZNF93; SOX13; NR1H2; FOS; MYCL; MBD2; SOX9; DLX2; CREM; SOX11; ZFHX3; ZNF232; ATF3; PITX1; ZMIZ1; OSR2; MYBL1
Down-regulation	127	TLE1; TSC22D3; STAT1; XBP1; TRIM22; CRK; FOXJ3; KLF2; TRIP6; IRF8; MED7; NFIB; HDAC6; HLTF; PHF8; EGR3; ZZZ3; ZBTB24; RNF6; SIX1; MTDH; RB1; SAP30; ZNF217; POU4F1; KLF9; CTBP1; MDM2; MED1; NUP62; BMI1; EZH2; BLZF1; THAP1; ITGB3BP; ZBTB18; ATF4; DNAJC2; BHLHE41; TERF2; ZNF267; REST; ZNF107; ZIC1; MSC; ZMIZ2; STAT5A; CRY1; BATF3; ATF2; RBM14; BRD3; ING2; SP3; GTF3A; TWIST1; ZMYM2; MED4; ZBTB11; BCLAF1; SMAD2; ZNF529; NAB1; C1D; GTF2IRD1; TMF1; ZNF146; ZNF432; ASH2L; RORA; HCFC2; RNF141; TAF10; ELK3; LEF1; FOXO4; HOXB7; EGR2; PPARG; HMGN3; SMAD3; PPARGC1A; SHOX2; MAFB; KAT6A; USP22; BLM; MEF2A; BATF; IRF7; ATF7IP; ATF1; BRPF1; CTR9; KAT7; DMTF1; KDM5D; CBX3; ASCL1; NCOR2; AHR; PMS1; MED6; HOXC6; NR2F1; DNMT3B; BAZ1A; ZEB2; BBX; NRBF2; ZKSCAN1; FOSB; RBPMS; ING3; KLF10; RFX5; PSIP1; KAT6B; HDAC9; SMAD1; TERF1; SFPQ; HTATIP2; MAGED1; BASP1; NR3C1; ETV1