Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID67660	Cyclopamine	GSE92742	ASC	Human	24h	10uM	EID0370

Response Information :

Types	Number	Response transcription factors
Up-regulation	163	NKX2-2; NKX3-2; JUN; ZNF500; FOXL2; ZNF444; SALL2; PIAS4; WT1; ZNF665; ZNF141; FLNA; DCC; HSF1; PRDM14; ZNF232; MYBL1; ZNF257; IRF6; ZNF770; HHEX; PBX1; NFATC4; ZBED2; FEZF2; ZNF350; ST18; CITED2; TULP3; FOXM1; ZBTB16; E2F4; POU4F3; TCF7L2; TCF21; TBX5; XRCC6; SMARCB1; BARX1; VGLL1; ZNF426; ZNF701; NFE2; MYCN; PSMC3; PEG3; HINFP; EN1; NFATC3; ZNF345; TEAD3; ZIC3; ZNF215; ELF4; BNC2; NR0B1; ZNF711; MXI1; ZFP36L2; TFEC; ZNF682; ZNF74; E4F1; CDK2; RING1; ZNF667; HDGF; SOX18; ZNF652; ZNF544; E2F8; CHD8; ZNF224; SPDEF; SAP30; GATA4; KAT2B; JUP; CDIP1; RXRA; HOXD11; GRHL2; ZNF239; MYCL; ATN1; RBFOX2; NKX2-1; PRDM10; HIRA; CUX2; PAWR; AR; RBM39; CERS4; MED14; MNDA; TFAP2A; MKL1; TAL1; L3MBTL1; HOXB5; CARHSP1; POLR3C; ZNF573; ZNF611; KLF11; VPS72; DEK; SOX3; ZNF692; FUBP1; NR5A2; KLF7; ZNF688; NR1H4; REL; FOXE1; GMNN; CNOT3; MEIS1; HIC2; PHIP; FOXF2; PBX3; ZNF91; DNMT1; THAP7; SOX17; ILF2; INSR; OSR2; TFAP2C; ZNF580; ARNT2; NFE2L3; GATA6; BTG1; HES1; MLXIP; TCERG1; ZNF117; HMGB3; CALR; ZNF93; NEUROD1; OVOL2; YBX3; TRIB3; TWIST1; ZNF43; THAP11; HOXB2; HOXB6; ZNF160; LIN28A; ZNF721; ZNF331; ZNF589; TOX3; ZBTB20; AEBP1; ZFP36L1; MEIS2
Down-regulation	176	TSC22D3; TLE1; MSX1; FOXJ3; KLF2; STAT1; BAZ1B; CBFB; CRK; TRAK1; XBP1; VGLL4; TRRAP; TSG101; KLF9; RNF6; TRIP6; SMAD7; SIX1; TSC22D1; BMI1; BCL10; USP22; MTDH; NFKB1; HDAC6; HEY1; HLTF; ITGB3BP; ATF2; MED4; REPIN1; FOXO4; YWHAB; PURA; ZFP64; NFIB; TRIM22; PHF8; DNAJC2; HIF1A; PIAS2; RBM14; ZZZ3; ZNF23; RNF14; RB1; BRD3; ZBTB24; NUP62; EGR3; CTR9; SPEN; SETD2; KDM5D; ELK3; STAT5A; MEF2A; HNRNPD; CRY1; DNAJC1; POLR2A; TAF7; BRD8; UBP1; MNAT1; NCOA4; ETV5; C1D; BATF3; USF2; SMAD2; BHLHE41; YBX1; FOXC1; HOXB7; NRBF2; NR1D2; CREBL2; JARID2; ASH2L; SMARCA1; RELB; ZNF468; HOXA10; ZIC1; ZEB2; MEOX2; BCLAF1; NFE2L1; SOX4; ZBTB38; ARID4A; SNW1; HMG20A; ZNF432; CBX3; ATF1; ZNF189; PPARGC1A; REST; BBX; MYCBP; ZNF107; GTF3A; ZMYM2; CHD1; MED1; ZBTB11; HOXC10; BRPF1; TAF10; NKX3-1; STAT3; BHLHE40; HMGN3; PAX5; UBE2B; EYA2; SMARCA2; NFATC1; SMAD1; CCNC; STAT5B; MED6; SERTAD2; KLF4; WWTR1; TRIM32; NRIP1; TMF1; ARID4B; POU4F1; HIVEP2; FOSB; BCL3; DDX5; RNF141; ING3; RARA; BCOR; SMARCA4; ZBTB18; SUB1; TBPL1; EGR2; PIR; ZMIZ2; IRF1; MAGED1; TCF4; KAT6B; AHR; MTA1; ID3; PCGF2; HOXC6; RUNX1; IKBKAP; SFPQ; MAFB; FOXD1; KLF10; LMCD1; DNMT3B; ASCL1; KLF6; DACH1; HDAC9; TGIF1; RFX5; CITED1; LEF1; NR2F1; POU2AF1; NR3C1