Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID67404	Dosulepin	GSE92742	ASC	Human	24h	10uM	EID0369

Response Information :

Types	Number	Response transcription factors
Up-regulation	327	ST18; HHEX; TXNIP; TAF5; ZNF124; E2F2; GATA3; ERBB4; AGO2; ZFP69B; PRDM10; BNC1; TCF21; LHX3; ACTL6B; ZNF74; THAP10; ZNF331; ZNF586; ZNF43; VGLL1; POLR3C; E2F1; ZFP36L2; RXRA; NKX2-1; ZNF329; ZFHX3; RBFOX2; NEUROD6; FOXE1; GATA2; ZNF562; ZBED2; PAWR; ING2; GATA1; TBX3; ZNF264; TAF5L; RBBP8; ARID3A; MKL2; CD3D; ZNF665; CCNE1; ARID1A; NR4A3; SAP130; ZFPM2; ZNF180; HIC2; ZNF257; CREB3L2; DLX5; NR0B1; IRF6; PHIP; SPEN; ZNF117; TAL1; TCF20; ZNF701; E2F3; JUP; ZNF85; PBX1; ZNF232; TAF1C; CREM; EMX1; RAD21; TGIF1; TAF1A; PRDM1; C1D; SAFB2; ELF4; MYBL2; SOX3; THAP7; TLE2; ZNF415; ZSCAN18; REL; ZNF174; MYCN; PRDM2; SNAPC4; HOXA3; TDP2; ZNF492; ZNF682; ZNF75D; ZNF223; DLX2; SKIL; MEIS2; ZNF8; KLF1; IRF2; GRHL2; ZNF215; ZBED4; MBD1; TOB1; BRIP1; ZNF274; STAT4; ISL1; ZNF557; ZFP30; DOT1L; BARX1; PPRC1; ASH1L; MYBL1; CAPN15; FOXH1; IRX4; NHLH1; PHF1; PAX6; CHD2; RREB1; CUX2; HMGB2; NR4A2; SUPT3H; NR3C2; MED21; ELK4; NEUROD1; HOXD1; HMGXB4; TAF9B; CDIP1; PAX1; ZNF652; TEAD3; NAB2; CBX4; BACH1; SNAI1; MNAT1; ANKRD1; ZNF112; ZHX2; TSC22D2; PEX14; ZFP36L1; ZIC3; RSF1; SALL2; TAF4B; FOXI1; NLK; DMTF1; CAMTA1; ZNF695; NFAT5; FOXF2; HDAC4; CBX7; SOX13; GFI1B; HOXA1; ZNF222; SKI; ZNF350; KLF13; SALL1; HINFP; ARID3B; KDM5C; BCL11B; ZNF93; PIAS1; WDR77; SSX1; ZNF512B; ZNF816; TBX2; ZBTB44; SOHLH2; GATA6; BLZF1; ZNF200; TUB; ETS1; ATN1; CCNH; E4F1; TFAP2A; GMNN; CBFA2T2; SIX6; HOXD13; KDM5B; ZNF91; IRF8; CREB3; ID1; LIN28A; CBFA2T3; CDK8; TEAD1; TBX21; SP2; TRIB3; ZNF273; CDC5L; RARG; NANOG; PIAS4; FOXF1; HBP1; ZNF239; CDK2; MED17; CREBL2; SOX21; ZNF141; SOX18; TOPORS; BRWD1; ZNF711; MECP2; FUBP1; ZNF268; NKX2-2; SAFB; TULP4; CBX2; ZNF217; ZNF443; CNOT3; TERF1; ZNF175; JAK2; MED14; ERF; SMARCA5; CITED2; TCF7L2; TULP3; E2F8; ID4; ZNF623; SOX17; OLIG2; TAF9; SOX9; OVOL2; KLF5; ZNF589; RNF6; ZNF532; NFE2; MNT; MED13; WT1; KLF11; ZNF354A; ZNF835; GTF2I; TRPS1; NR1D2; SMARCC2; URI1; NFYA; PRDM14; FOXM1; MYCL; TGFB1; TCF3; DACH1; ZBTB16; HMGB1; FOXG1; PHF20; UBE2B; EGR2; ZNF195; CTCF; TCF4; SP3; TFAP2C; ZBTB1; MYT1; ENY2; DAXX; SATB1; KLF10; PPP1R13L; TFDP1; TP63; ETS2; HIRA; SUPT4H1; VEZF1; CRYM; INSM1; SPIB; TFDP2; SFPQ; MNDA; NFE2L3; ARNT2; FOXN3; MEF2C; ZNF544; VPS72; TGIF2; BCL11A; NR4A1; FOS; BHLHE41; ZNF165; DNMT1; ZNF423; VDR; NR2F1; MAFB; KAT6B; SOX11; PEG3
Down-regulation	300	PUF60; CRK; EDF1; UBE2I; TLE1; YBX1; ENO1; HLX; PSIP1; FOXJ3; MMS19; FHL2; TRIM28; USF2; TP53; ASH2L; SSRP1; MDFI; TAF10; SMARCD2; ZNF302; ATF4; MLXIPL; CEBPA; FOSL1; RBPJ; STAT1; SIX2; TRIM22; NCOR2; PARP1; CCNA2; PCBD1; NELFB; NEDD8; SMARCE1; MSX1; NUP62; ELK1; CSDE1; ARNT; ECD; REST; ATF5; NFKBIA; TRAK1; TRIP6; BTG1; ERCC2; MED6; PRPF6; ZNF146; RHOA; SREBF1; KLF6; HDAC6; KLF12; HDAC2; RELA; BRF2; BATF3; HOXB3; YBX3; KMT2B; TBP; APEX1; SIAH2; SIX1; PDLIM1; ZNF83; SP140L; FOXD1; ZSCAN12; ZNF408; HOXC6; CLOCK; PHF8; ZNF783; ZKSCAN1; CERS6; BCL6; HOXB7; SND1; POU5F1B; ZNF646; FOXO1; ZNF3; SP100; SETD3; HDAC7; ZNF672; BAZ1A; REPIN1; TSC22D3; MSL3; ERCC3; ATF6; BCLAF1; RUVBL2; KAT8; MEOX2; RFXANK; ZNF787; WHSC1; TBL1X; EMX2; CNBP; HCFC2; SETD2; GABPB1; WIZ; NONO; CHD9; FOXO4; MED23; ORC2; HLTF; NR2F2; VGLL4; KDM2A; MAZ; RNF10; NR2C1; STAT6; HMGB3; CXXC1; WWTR1; SUV39H1; CNOT1; ZNF133; TAF1D; CREB3L1; NPM1; DPF2; ZBTB48; ZNF84; MAX; BCL3; SLC2A4RG; FLNA; MTF1; C1QBP; PBRM1; HMG20B; SMARCC1; CTR9; ZNF768; CEBPG; GATAD2A; AATF; HMG20A; PREB; TSC22D1; DNAJC1; MED24; MEF2A; BMI1; BRPF1; NCOA4; TRIM16; HOXC10; ZNF292; TSHZ2; RAN; HSBP1; RFC1; TRIP4; HDAC1; KDM5D; RBM14; CREG1; SF1; PLAGL1; MED1; HTATIP2; ZNF692; NR2F6; THAP4; PBXIP1; BRD8; ARID5A; RNF141; HOXB2; CBFB; TBX10; SCMH1; AIP; CASZ1; EBF2; RBM39; KDM4A; ZNF24; UBP1; CENPF; ZNF160; HIVEP2; BNC2; SIRT7; ZEB2; KAT7; MBD4; HEY1; NRBF2; LOXL2; ZNF189; PEX2; EYA1; PRRX2; NFE2L1; NR1H3; XBP1; KAT5; FOXC1; ALX1; MAF; PA2G4; TAF7; SNW1; ZMIZ2; PATZ1; SMARCA2; STAT5A; ZNF337; TCF12; NFKB1; MTDH; MLX; NFYC; NAB1; RUNX1; KLF7; TCF15; PMF1; ATF3; MYNN; EHMT2; SUZ12; PRMT2; ZNF212; MITF; ZFHX4; SERTAD2; ERBB2; SMARCD3; TOX4; HMGN3; ETV6; MSC; ZNF248; PCGF2; KLF2; LPIN2; POU4F1; ZMYND8; ZIC1; CRY1; RBBP7; BHLHE40; BAZ2B; PITX1; TGFB1I1; ERG; TLE4; ZBTB11; ARID4B; RBPMS; HNRNPD; ELK3; DEAF1; DNMT3B; USP21; SPDEF; EZH2; IFI16; TSC22D4; WNT4; KLF4; RUNX3; HOXB6; MECOM; ELF3; IRF1; IRF7; TCEA1; PIAS3; EYA2; PPARG; YWHAB; TWIST1; EHF; TCERG1; NKX3-1; PIR; MYB; PTTG1; RFX5; FOSB; LEF1; IKBKAP; NFIL3