Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID67337	Midostaurin	GSE92742	ASC	Human	24h	10uM	EID0369

Response Information :

Types	Number	Response transcription factors
Up-regulation	189	PPARD; KDM5A; HLX; HHEX; NCOA3; ELF4; ST18; PRDM10; MKL2; ZNF180; JUN; TCF21; SPEN; JUP; SPI1; ZNF32; MED12; THAP10; FOXO1; TXNIP; TFAP2C; SALL2; SOX17; WT1; CHD4; ZNF350; NFAT5; ZFHX3; ZNF75D; ZNF112; TTF2; ZNF174; ELK4; CREB3L2; NR1H4; VGLL1; SIX6; SRCAP; PEX14; PRDM12; TBX3; TRPS1; MAFB; NKX2-1; FOXE1; HBP1; THAP7; ZNF200; NFE2L2; ZNF492; ZNF331; ID4; MED14; SMARCB1; DLX5; IRF6; NFE2; TAL1; ZFP36L2; MEIS1; ZNF354A; CDC5L; HOXB1; LZTR1; ZNF623; HIVEP1; ZNF268; NFATC3; TAF12; OSR2; ZNF232; PHF1; E2F3; TCF20; TULP3; EP300; GRHL2; CBFA2T2; ZSCAN31; DLX4; SKI; E2F8; MYBL2; TFAP2A; ING4; PFDN5; SALL1; BACH2; HOXB13; TCEA2; OLIG2; CALCOCO1; ZNF444; NR4A3; FOXL2; ARL2BP; LPIN2; TRIB3; ZHX2; TWIST1; ZFPM2; SSBP2; NFE2L3; SAP130; SOX3; VPS72; SOX13; EN1; ZNF45; KDM5C; CREB3; RRN3; MYBL1; NR5A2; TRIM33; GMNN; HIC2; ZNF124; MYCN; KAT2A; ERBB4; FOXF2; SUPT4H1; BACH1; DDIT3; ILF2; HOXA1; ARNT2; ING2; DLX2; RAD21; SUPT3H; PBXIP1; TERF2; BCL11A; ZNF43; WWP1; SHOX2; IRF8; CTCF; PQBP1; FOXM1; PHIP; ELF5; HOXD1; NR0B1; VDR; ZNF468; CUX2; SP2; ZBED1; TDP2; ZNF117; FOS; TRIM29; ZNF532; KLF13; TFDP1; HIPK1; ZBED2; ZBTB16; TCF7L2; KAT2B; TGIF2; UBE2B; HIRA; ABL1; MYRF; ESR1; NFIL3; FUBP1; BHLHE41; GATA6; CDK2; CREBL2; NKX3-1; MXI1; SNAI2; PEG3; ATF3; ZNF423; NCOA2; TSC22D3; NR2F1; ID3; DNMT1; MNDA; HOXA5; ID1
Down-regulation	176	CRK; NR2F6; FOSL1; FHL2; STAT1; CCNA2; YBX1; TP53; BMI1; BCLAF1; ZKSCAN1; SMAD7; UBP1; SUV39H1; CLOCK; RBM14; ENO1; TRIM28; HNRNPD; ZNF23; MED6; PITX1; NUP62; HMGN3; ZNF302; YWHAB; GATAD2A; C1QBP; CTR9; HDAC2; TRIP6; BAZ1A; ERCC2; NRIP1; CENPF; DNAJC1; EDF1; ZNF430; POU2F1; HLTF; ORC2; TRAK1; DDX54; MYC; ZNF672; RNF141; SMARCA4; ZMYND8; PSIP1; ATF6; CITED1; ECD; ZNF692; URI1; HMG20A; SIAH2; MSX1; NELFB; CBFB; RELA; PA2G4; REPIN1; ZNF44; HMGB2; ZNF783; DR1; SMARCA5; MYCBP; NPM1; KLF6; KDM5D; XBP1; MSC; PREB; TRIM22; ING3; ASH2L; ELK3; CARM1; ZNF281; SND1; FOXD1; CCNC; ZNF787; ZNF146; NLK; CALR; RBPMS; E2F5; TAF10; BANP; CHD9; TSC22D2; NCOA4; DDX5; LZTS1; ESRRA; RORA; FOXJ3; TBP; NFIC; RBBP5; DNAJC2; SUB1; AES; MXD4; ZBTB38; DNMT3B; SIX1; LOXL2; SIX2; PIAS2; STAT6; MAGED1; PTTG1; CNOT1; ELK1; TCF12; IRF4; ZBTB11; RUVBL2; KDM4C; ARID4B; NFKB1; TBL1XR1; MED24; ZEB2; IRF1; TRIM32; RUNX3; TRIM16; PMS1; IRF2; TSC22D4; TCERG1; WWTR1; PIAS3; HES1; JARID2; HIVEP2; BHLHE40; CBX3; SMARCA1; ZZZ3; BATF3; CREB3L1; ZBTB18; SFPQ; CDYL; KLF7; SMAD2; ZMIZ2; MED1; BASP1; RFX5; SMAD1; PURA; KAT6B; EZH2; HIPK3; CEBPZ; BAZ2B; TOX; RAN; ERBB2; KLF2; EMX2; MTA1; EGR3; HOXC6; TBL1X; ZNF91; IKBKAP; POU2AF1; DACH1; CREB1