Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID67139	Dosulepin	GSE92742	ASC	Human	24h	10uM	EID0368

Response Information :

Types	Number	Response transcription factors
Up-regulation	303	CREB1; TBX2; GATA3; BTG1; MED13; KMT2A; ZNF93; MYB; CD3D; WNT4; BAZ1A; EGR2; EGR3; E2F5; CNOT6; PBX2; NOCT; FOXO1; CUX1; MAML1; TRPS1; NFE2; CHD7; TXNIP; MKL1; ARID3A; CREBZF; ZBTB44; DNAJC2; ZNF586; IRF4; ZNF711; HSBP1; TSC22D2; KLF10; ZNF195; CHD1; RBM14; SERTAD2; BCL11B; SMAD4; DEAF1; NPAT; SMARCA1; RARG; PLAGL2; NLK; ZNF778; PHOX2A; TCF7; SSX1; ADNP; PEG3; TRIM22; IRF9; ETS2; URI1; RELA; ZNF253; ZNF430; NFX1; BACH2; REL; IKZF1; MXD1; EP400; HINFP; ASCL1; CBFA2T3; RSF1; PAX5; TCF20; NR1I2; CREB5; SIX3; TRIM29; STAT4; SPDEF; ZNF556; KDM4A; PSMC3; SPIB; TFDP2; HCFC1; CHD3; NR3C1; NFATC4; PHOX2B; BRWD1; ZFP36L1; PAX1; SOX2; RBBP5; BAZ2A; CCNE1; DPF2; RYBP; HMG20A; DACH1; HMGB1; LZTS1; WT1; TOPORS; ZKSCAN1; TRIP11; ZNF701; ZNF629; PROX1; NAB2; TMF1; SOX21; TRIM33; PRDM5; ZNF200; GRHL2; SKI; ZHX2; WHSC1L1; LEF1; AGO2; ZNF124; NFYC; KLF9; PHF8; ESRRA; ZNF165; EGR4; GATAD2A; PRRX1; ZNF43; OVOL1; NRBF2; CREB3L2; ZNF506; LPIN2; BLM; NFYB; E2F6; MEN1; PAWR; ID4; TGFB1; SNAI1; ASH2L; CBX5; SOX10; CCNT1; ZNF672; BCL10; ZBTB43; IRX5; TAF4; RARA; NEUROD1; EPAS1; BPTF; RCOR1; VEZF1; RXRA; MTF2; FOXE1; E2F2; MYCN; SP1; HMGB3; FOXA1; TAF10; PURA; ZNF143; ZNF281; PTTG1; NFAT5; NR1D2; TP63; GLI3; ZBTB39; NFATC3; TULP4; TAF12; BACH1; MED1; ZNF117; BCOR; OVOL2; DBP; SOX13; CBX6; ZNF75D; PAX6; BRIP1; THAP1; GTF2IRD1; HOXA1; FOXL2; CARF; TRIM25; DMRT1; CAMTA1; ORC2; NR0B2; SHOX2; ZNF22; VDR; SIM2; HLF; ADRB2; ARID4A; ZNF202; HIPK3; CTR9; SMARCE1; ERBB2; ZBED2; SP140; CHD4; TAF1; UIMC1; HDAC9; IL16; DLX5; DLX4; SALL2; ZFHX3; RNF141; FLI1; HOXC10; LYL1; SSBP3; SMARCA5; ELF3; ZBTB20; NR0B1; ZNF189; BRD7; ZNF557; ZBTB48; BASP1; CERS6; ZNF443; CDX1; ZNF107; GATA6; SOX11; VGLL1; ZNF587; RUNX1; CREM; NKX2-2; HLTF; MXI1; CARHSP1; TAF9; BAZ1B; HOXC4; GTF2I; ZNF665; KDM2A; UBE2B; MED20; RERE; BCL11A; PITX1; YAP1; BHLHE40; IRF5; ZBTB38; MYT1L; MNDA; ZNF160; SOX5; CCNA2; ESR1; TOX3; TBL1X; KLF7; WWC1; IRF8; RNF14; NKX2-1; ING3; ZMIZ1; HIVEP2; ZNF721; ZNF331; IRF6; ZNF232; HIC2; STAT6; BNC2; STAT3; OLIG2; ZEB2; AHR; NCOA1; AEBP1; TRIP6; TFAP2C; POU2AF1; MAF; ZNF652; ID1; INSM1; CRK
Down-regulation	252	VGLL4; PUF60; TCEA2; CEBPD; RHOA; ABL1; GTF3A; TSC22D3; NELFB; HMGN3; LOXL2; NR2C1; ARID5B; MTA1; HOXA10; ERCC3; TCF15; IRF3; ZNF580; HIF3A; ATF4; TGFB1I1; ZBTB17; FOXJ3; SETD2; ZNF593; ZNF133; PMS1; HOXB13; CDYL; SUB1; ETV4; HOXB3; ADNP2; TDP2; LHX1; TBX10; CBX3; KAT2B; ZZZ3; POU5F1B; DLX2; FOXG1; THAP10; ZBTB16; HOXD13; ZSCAN18; MED27; ZSCAN12; HOXA7; ZNF32; FLNA; ARL2BP; PSIP1; KLF2; SIX2; PHF1; RNF6; PPARG; PCGF1; TBX19; PTRF; CREG1; VSX1; PBX1; FOXC1; CRX; ZNF83; SCAND1; KAT2A; GBX2; LMCD1; RFXANK; NKRF; MYF5; ZMYM2; MDFI; TRIM16; EVX1; MYOG; ZBTB7A; KAT7; IKBKAP; UTF1; NOC2L; CTBP2; PMF1; RBM39; ZNF337; RBBP7; DNMT3B; NPAS2; LZTR1; KDM4C; ZSCAN5A; PHF20; ZNF219; TCEA1; ZNF787; ATF2; DR1; HDAC3; ARID5A; SATB2; NRIP1; PITX2; XRCC6; TRIM32; ZNF84; EYA1; ZNF302; BRD8; ZNF589; MEF2D; ZNF432; EWSR1; KMT5A; KLF6; ZMYND8; SOX9; TBX3; TRAK1; SSBP2; FOXM1; ZNF529; PIR; APEX1; ING4; EDF1; TLE2; POLR3F; HDAC7; ZNF426; NCOA6; COPS2; RUVBL2; ZNF205; YBX1; YBX3; RLF; POU4F3; TDRD3; MED24; UBE2I; HLX; ZNF263; ZNF688; ELK3; SOX17; CDK9; EMX2; PLAGL1; ZNF468; MED17; ZNF512B; ZFHX2; NFIX; ZNF226; NFE2L1; RNF138; NONO; HCFC2; CRY1; TSC22D1; AES; SMAD7; EYA2; ATN1; ZNF268; CEBPB; MAGED1; CHD8; HDAC1; TEAD4; ZBED1; ETV5; LIN28A; MED23; ZNF358; ZFX; C1QBP; MYRF; ZNF184; POU4F1; DNAJC1; THAP11; CEBPZ; ZNF573; EN1; TCF7L1; CBFB; BCLAF1; ETV1; MEOX2; LITAF; AIP; PEX2; NR1H3; HOXA4; RBBP4; CNOT1; ZNF423; CENPB; NCOR2; PEX14; TULP3; CALCOCO1; ARID1A; ZNF532; SOX15; OSR2; CERS4; HOXB6; CARM1; HEY1; DMTF1; NANOG; SMAD1; KLF4; CREB3L1; DDX5; CBFA2T2; AR; ESRRG; RFX5; BMI1; CDC5L; PSPC1; KAT6B; CDK8; NFIB; WWTR1; SAP18; SOX12; BCL3; MAFB; HOXB7; HES1; CITED2; SAP30; FOXF1; ZFP36L2; HMGB2; MEIS2; NR2F2; SPEN; NFIL3; PCGF2; FOS; FHL2; ZNF91; HOXB2