Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66965	Vorinostat	GSE92742	SKB	Human	24h	10uM	EID0367

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	MTF2; HOXA5; HMG20B; RUVBL1; THRA; WWC1; ACTL6A; RUVBL2; DBP; NOC2L; VPS72; PARP1; ID2; ZNF589; SATB2; TCF21; ZNF133; KAT2A; RERE; MKL1; PSIP1; CBFA2T2; ENO1; CCNC; ZKSCAN4; UBE2L3; CBX4; MXI1; CCNH; CHD4; PIAS1; SPIB; MYBL2; SOX4; IRF6; TRIM24; DACH1; NFE2L3; CDIP1; SMARCD3; CRYM; PBX3; SALL2; DLX2; TCEA2; MKL2; LEF1; ID3; FOSB; ZNF467; ASCL1; MYCBP; ZNF665; CERS6; THAP7; DLX5; HHEX; NFE2; TCEB2; HDAC1; PRKDC; CDK2; FOXF2; INSM1; HOXB5; TGFB1; ZNF331; WNT4; SERTAD2; ZNF232; TLE1; MYBL1; HOXD1; BCL11A; WT1; NFIL3; ATF3; SSBP2; CALR; PHIP; HOXB6; GTF2A2; CARHSP1; HDAC9; TOX; TRIB3; ID1; NKX2-1; SOX9; TFAP2A; LITAF; HOXB2; ZNF91
Down-regulation	154	ZMYM2; TP53; USP22; PUF60; ERBB2; ZEB2; ZHX2; ATF5; PATZ1; PCBD1; SFPQ; KLF2; EWSR1; PBRM1; UBP1; TRIP6; SIAH2; FOSL1; SMARCC1; ATF1; BACH1; NFE2L1; PHF2; PLAGL1; CSDE1; TRIM22; HMGB2; STAT6; TGIF1; ZBTB38; SP3; ATF4; ZNF432; SMAD4; GABPA; XBP1; SP140L; CTNNB1; WHSC1; PMF1; HMGB1; ZIC1; MEOX2; CARM1; RCOR3; NCOR2; NFYB; CTBP1; MYF6; PSPC1; ZZZ3; ZBTB20; GABPB1; ELF1; ZBED1; CREB3L1; RNF6; BCLAF1; GTF2IRD1; YAP1; SUV39H1; ZBTB1; ZKSCAN7; ZNF264; KAT6B; DDX5; NFKB1; TMF1; BASP1; TSC22D2; ZNF189; HIPK3; COPS2; MSC; FOXO4; PHF8; CBX5; TRRAP; MAGED1; PRMT2; ZNF302; TBL1X; BAZ1B; ARL2BP; RRN3; RBBP4; ZFP36L1; STAT4; PRRX1; SAP30; BAZ2B; REST; ZNF536; CBFB; HMGA2; BPTF; MAF; TGFB1I1; BRD3; USF2; RBM14; BHLHE40; EYA2; IRF2; MTDH; POLR2A; MAX; ARID4A; PLAGL2; RNF10; GATAD2A; GTF3A; PPARG; HOXC4; RREB1; ELF5; BAZ1A; HOXC6; NR1D2; SHOX2; HDGF; SMARCA4; NUP62; BTG1; TEAD4; SAP18; KLF4; HOXB7; PBX1; ZBTB43; ING3; KDM5D; NFIB; MED1; NRIP1; FOSL2; MEF2C; WWTR1; ZNF512B; KLF10; CEBPG; FOXD1; ZMIZ1; KLF5; ZBTB18; FOXM1; CHD1; MSX1; LMCD1; KLF6; BMI1; CREB1; MAFB; RELB