Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66951	Pirfenidone	GSE92742	SKB	Human	24h	10uM	EID0367

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	BCL11B; ZBTB14; SMARCA2; BRIP1; KAT6B; PLAGL1; RBBP5; RBL2; NFIB; IRF4; TOPORS; TMF1; ZNF430; ZNF165; SMARCA1; NKX3-1; SATB1; TGIF1; TFAM; BCLAF1; CEBPZ; BRD8; TXNIP; TSC22D1; ZNF783; NR1D2; IRF1; PURA; FOXJ3; DBP; TOX3; TBPL1; ZNF267; ELF5; HLF; GATA2; SKI; BTG1; EYA2; TBP; MAFF; LPIN2; ID2; EZH2; LEF1; NAB1; SUV39H1; ZNF711; ARID4A; ORC2; ZNF468; TBL1XR1; TCFL5; PNRC1; SMARCD3; NR2F2; PHF8; CREB3L1; TAF7; NFAT5; ISL1; ASCL1; EHF; ZNF516; SNAI2; MYCBP; HIVEP2; WWC1; NEDD8; ETS2; RYBP; ZIC1; HSF2; ATF1; TTF2; FOXA1; BHLHE41; ATF3; TBL1X; CREB5; FOSL2; SATB2; PRKDC; EBF2; MXI1; TFDP2; CD3D; SIM2; ZNF226; HBP1; CRY1; ZNF551; RFX5; HMGN3; HLTF; TBX3; TSC22D2; NR4A2; SIX2; SUZ12; SIX1; PEG3; PIAS2; ID1; EDF1; EGR3; ARID4B; MED1; GTF2A2; NRIP1; BCL11A; KDM5D; ID4
Down-regulation	99	NR2F6; ZMYM2; CREG1; HR; ZNF219; ZNF768; ZNF444; CARM1; CDX1; SFPQ; E4F1; HIC2; SF1; ARL2BP; FLNA; YEATS2; ZEB1; SIRT2; ATOH1; MED25; MXD3; ZMIZ1; NFIC; HMX1; HOXA10; SPEN; PITX2; ZFP36L2; SMARCB1; NCOR2; TEAD4; GTF3A; JUP; HLX; POU2F1; XRCC6; PA2G4; KLF13; TRIM28; LZTR1; HOXA11; RLF; ATN1; HDAC7; ZBED4; MEF2C; HIPK2; LDB1; TGFB1I1; ZNF580; INSR; CDX2; MYRF; CHD7; EPAS1; HMGA1; RXRA; TSG101; CNOT3; ARID3B; GATAD2A; MED15; JUND; TGFB1; SOX18; SIX3; PSMC3; MAZ; KLF4; HHEX; SOX17; ZNF423; CITED2; ERBB4; HIRA; SHOX2; PLAGL2; PBX1; NR5A2; TFEB; KLF7; CTBP2; TAF10; LIN28A; NONO; BRD4; ZNF467; ARNT2; PTRF; IRF7; VPS72; HMGB2; MEOX2; EHMT2; HOXD1; ZNF281; TRIM16; EMX2; POU2AF1