Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66508	Desmethylclozapine	GSE92742	SKB	Human	24h	10uM	EID0366

Response Information :

Types	Number	Response transcription factors
Up-regulation	138	MYBL2; HES1; THAP7; DAXX; CEBPG; ZNF117; TAF4B; PHIP; ZNF43; SUMO1; ZNF195; SSBP3; HOXB1; HDAC9; ATN1; WT1; ZNF232; ZNF331; IRF9; CBX4; ATF3; TAF5L; CDK2; ZNF74; MEIS2; CBFA2T2; TP73; SPDEF; TDP2; PBX3; ATOH1; CNOT6; MXI1; NFATC4; NAB2; E2F8; DEK; TOX; IFI16; ZNF682; KDM5C; KLF11; ZNF415; ZNF141; SIX3; ZNF239; ZNF85; ZNF467; DNMT1; TTF2; ZNF835; NR2F1; ZNF268; WNT4; RAD21; IRF6; SALL2; JUN; MYBL1; ID4; HIRA; ZNF623; ZNF140; PSMC3; TP63; ZNF675; PEG3; CALR; TRIB3; NEUROD1; ZMIZ1; RARG; ZFPM2; SOX2; HOXD1; TFAP2C; TCEA1; ZNF345; TULP3; FOXF2; BRIP1; FEZF2; E2F5; INSM1; NR4A2; ZHX2; CDIP1; ZNF264; ZNF354A; ZNF91; NFE2; ESR1; NFYB; ETS1; VPS72; AEBP1; TFAP2A; JUNB; CREBL2; DDIT3; HBP1; TRPS1; BACH2; FOXM1; BNC2; SOX13; PBXIP1; THAP10; HSF1; NKX2-1; POU2AF1; CBFA2T3; RBBP8; ERBB4; ZFP36L2; SOX17; ARNT2; PAWR; ZNF165; ZNF423; CTBP2; GMNN; FOXA1; GRHL2; NKX2-2; SMAD1; BHLHE41; INSR; PBX1; EHF; TBX3; ZBED2; ST18; OSR2; EMX2; DLX2; ASCL1; HEY1
Down-regulation	161	SIAH2; FOXJ3; TRIM16; IKBKAP; TBP; UBP1; SMARCA4; BCLAF1; NCOA4; RCOR1; PSPC1; FOXO4; RB1; CBX3; NUP62; DR1; BHLHE40; MSX1; MAGED1; ZMIZ2; TAF1D; FOXD1; ZBTB18; RHOA; TSC22D2; EDF1; ARID4A; CITED2; SMARCA2; NR2F2; CASZ1; ELF1; NEDD8; BRPF1; FOXO3; REST; MAF; BRD8; ASH2L; ZEB2; YBX1; RLF; ENO1; TRIM28; RNF14; USP22; RBBP4; BATF; ASXL1; NFAT5; ECD; NFKBIB; HOXC6; TULP4; NFKB1; RBM14; PIAS3; PIAS2; ARID4B; HNRNPD; CCNA2; MYCBP; KDM2A; TCF15; HSBP1; MSC; RUVBL2; TBL1X; SFPQ; SOX4; STAT1; PPARG; TLE1; RNF141; POLR2A; ID2; KDM5D; DNAJC1; DDX54; YWHAB; REPIN1; PIR; BMI1; TBL1XR1; CRY1; BAZ2B; MED23; TAF10; NR1D2; ZNF410; FOSL2; STAT3; SETD2; RELB; HIVEP2; SMAD3; ZNF226; KLF4; PTRF; ING2; EZH2; NFIB; MED1; SAP30; KDM5B; BCL10; BRD3; ZBTB11; SMARCA5; BASP1; NCOR2; PCGF2; TRIM32; SIX1; MEF2A; TMF1; ATF1; ZBTB38; NFE2L1; KLF6; MITF; PHF8; BRD4; KAT7; ZBTB43; FLNA; TCEB2; JARID2; NELFB; BTG1; AFF1; GABPB1; FOSL1; SP3; BATF3; TP53; BCL3; ELK3; ETS2; TCF4; ZNF217; HLTF; RNF10; WWTR1; RFX5; BBX; NAB1; TRIP6; ZNF148; CTR9; HMGA2; TBPL1; MTA1; KLF2; MNAT1; IRX5; MEF2C; ING3; MAFB; XBP1; ERBB2