Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66344	Brimonidine	GSE92742	SKB	Human	24h	10uM	EID0365

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	MED1; KDM2A; SMARCA2; NUP62; EYA2; NAB1; BCLAF1; SMAD3; STAT5B; ZNF783; CRY1; EDF1; ADNP; BRPF1; RNF14; SMARCE1; SIX1; RNF6; EGR1; ZBTB38; SMAD2; MEF2A; EZH2; DDX5; SOX15; GTF2IRD1; PURA; ZMYM2; NRBF2; PPARD; HLTF; TRIM32; NEDD8; PHF2; PIAS2; BRD3; ZNF24; FOXO4; PPARGC1A; NR1D2; NCOA6; MSC; STAT5A; KDM5B; MSX1; ZNF146; DPF2; ATF1; ING3; SETD2; BMI1; BATF; HOXC6; MYT1L; RBM14; CHD3; HIF1A; MTDH; NELFB; BHLHE40; ZMYND11; ING2; ZBTB43; LMCD1; TBP; ARID4A; MBD2; RNF111; C1QBP; TADA3; RBBP4; FOXD1; UBP1; ELK3; RUVBL2; MAFB; AHR; ZEB2; TXNIP; NFKB1; SAP18; EGR2; ZBTB18; SFPQ; CTR9; HSF2; SATB2; HNRNPD; RNF4; SMARCA4; ELF1; SAP30; KLF9; CITED2; ZNF189; HOXA10; TSC22D2; HOXC10; FOSL2; ARNTL; CBX3; NFIL3; BCL10; AFF1; PITX1; HSBP1; MAGED1; JARID2; FOXJ3; ZBTB1; BASP1; NR1H2; NR2F2; RBBP7; FLNA; KLF5; NRIP1; SPEN; ABL1; MAF; HEY1; HMGN3; MNAT1; USP22; EGR3; KDM5D; VGLL4
Down-regulation	105	PDLIM1; MYBL1; DNMT1; ZNF239; POU2AF1; HIRA; IRF9; ZNF107; MEIS2; ZHX2; CDK2; ZNF273; TAL1; HHEX; ZNF117; ESR1; ZNF43; ZNF74; MYBL2; GMNN; NFE2; TTF2; TCF21; TCF3; PIAS4; DLX2; ZNF350; ZNF544; EHMT2; PBX3; ZNF195; BCL11A; ZFPM2; BACH2; ZNF274; STAT4; ARNT2; ZNF268; SUPT3H; ZNF394; E2F8; TFAP2A; ZNF85; TFAP2C; NFE2L3; ZFP36L2; IRF7; CREG1; ZNF140; HOXB2; CERS4; FOXF2; TDP2; NKX2-1; SP140L; POLR3C; TCF7L2; PSMC3; PBXIP1; AEBP1; CRYM; PFDN5; SOX17; SSBP3; ILF2; SIX3; LEF1; EMX2; ZFP69B; WT1; MLXIP; LIN28A; HMGA1; IRF6; JUN; IFI16; JUP; ZNF423; CD3D; TERF1; FOXM1; JUND; ATN1; ZNF91; REL; TCEA2; HMG20B; NR2F1; PBX2; NR1H4; BNC2; GATA6; MYB; RSF1; TFEC; ZNF551; ATF3; ZSCAN18; CHD7; EN1; MXI1; LITAF; PAX5; ZNF586; NFATC3