Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66183	Vorinostat	GSE92742	NPC	Human	24h	10uM	EID0364

Response Information :

Types	Number	Response transcription factors
Up-regulation	133	EGR1; BRD4; HMG20B; MLXIP; NR4A1; UBE2B; FOS; FOSB; FOXO4; LMCD1; KLF6; TOB1; ATF3; EGR3; JUNB; JUN; ETV5; CRK; STAT1; CREG1; CBX7; HOXD1; NFIC; ZNF593; EHF; JUP; HBP1; BCL3; KLF9; USP16; TERF2; MYCBP; JUND; KLF10; NOC2L; CRYM; NR3C2; IL16; SUPT5H; ACTL6A; ZNF331; RNF6; ARID5A; NR4A2; CEBPB; MED15; CREM; SNAI2; NR4A3; BBX; TFAP2C; MTF2; SATB2; SUMO1; EGR2; PHIP; IRF9; HLF; SPDEF; MAK; PIAS1; CCNC; HHEX; KLF4; ERBB4; SP100; MBD2; TBPL1; SUB1; PRRX1; ANKRD1; GTF2A2; SERTAD2; SOX13; MAFF; VDR; ZNF394; TOX; WWP1; SOX10; TFAP2A; AHR; TSG101; ZNF224; ASH2L; HIVEP2; BCL10; ELK3; CCNH; NFAT5; EN1; PPARGC1A; ZBTB20; NR1D2; TFCP2L1; ZNF304; NFIB; DNAJC2; RAD21; CREB3L2; ZNF430; ELF5; KLF2; DDIT3; CREBL2; MLX; ZNF160; ARID5B; NANOG; MITF; CDK7; RBPMS; ZNF91; ZBTB16; WWC1; SMARCA2; SOX9; ERG; TULP3; TRIB3; ZSCAN18; SAFB2; ZNF44; CD3D; TLE2; IRF6; TRIM29; KLF5; BHLHE41; TGFB1; CITED2; TP63; PPARD
Down-regulation	225	PUF60; TP53; SMARCA4; SOX11; SOX4; HMGA2; CARHSP1; EYA1; TCERG1; ZNF22; GLI2; ZNF532; PATZ1; SOX2; PHF2; PCGF2; BAZ2B; ZBED1; NFKBIA; LIN28A; RAN; SALL2; ZFY; RBBP4; MYCN; PMF1; DEAF1; ZNF140; CBX5; YAF2; ARID4B; NFKB1; PARP1; CCNA2; SCMH1; HMGB3; CENPF; MEIS1; BAZ1A; NCOR1; SIX2; SUV39H1; CDK8; ASXL1; ZNF282; PSPC1; ZKSCAN7; KDM5B; GABPB1; NHLH2; ENO1; EZH2; MMS19; ZBTB1; SMARCC1; ERBB2; TGIF2; ZNF783; ZNF629; TLE4; DNAJC1; SALL1; CREBZF; ZNF292; ZNF84; PRMT2; HDGF; WHSC1; HNRNPD; DAXX; CHD7; TFDP1; FOXO1; PBX3; SSRP1; SMARCE1; LPIN2; NAB1; SMARCD1; VGLL4; USP21; RFX5; ADNP; EHMT2; ZNF32; TCF7L1; ASCL1; DACH1; RXRG; BRD7; STAT5B; PBRM1; TBL1X; CHD3; TCF12; DNMT3B; TBP; ZIC3; ZNF189; PCBD1; HOXC4; LHX2; BATF3; ZNF146; OLIG2; HOXD11; BRD3; ZNF516; TCF4; GTF2IRD1; TRIM28; CUX1; TBL1XR1; ARRB1; HEY1; KAT7; MBD4; RSF1; PLAGL2; ZNF423; CUX2; KAT5; TAF1D; ZNF177; HOXB2; WIZ; EDF1; YBX1; ZNF672; HMGB1; PLAGL1; SMARCA5; MAF; USP22; NR2F2; BCLAF1; BASP1; TCF3; E2F2; RHOA; SMAD6; MAGED1; BTG1; TAF9B; HIC2; RBM39; STAT6; RBM14; HDAC3; TRIM16; SREBF1; NRIP1; MEIS2; FLNA; UBTF; RFX7; FOXD1; SIAH2; UBE2I; DDX17; PBX2; RBPJ; CHD9; REPIN1; TOX3; ZFP64; HIRA; VEZF1; FOXM1; ZFP36L1; BRD8; PQBP1; PITX2; SSBP3; ZEB2; NUP62; HDAC2; ZSCAN31; MAZ; GTF2I; DLX2; PBX1; APEX1; PFDN5; TCEB2; TGFB1I1; BCOR; ZNF467; KAT6B; BCL6; ZNF24; ZEB1; BCL11A; C1QBP; MGA; AR; YAP1; EYA2; ISL1; MECOM; PMS1; NCOA2; HOXC6; KDM5D; PITX1; EMX2; FUBP1; ID4; SP3; KAT2B; FHL2; ETV1; LEF1; CTNNB1; HOXB7; BMI1; ATF5; MSX1; HMGN3; PAX6; LOXL2; TXNIP; FOXF1; ESR1; MTA1