Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66170	Pirfenidone	GSE92742	NPC	Human	24h	10uM	EID0364

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	UBE2B; HOXD1; EGR3; FOXJ3; TERF2; RAN; CHD1; SATB1; BBX; MEOX1; NFYB; TERF1; EGR2; MED7; TAF9; TRIM22; IKBKAP; ZNF107; RNF6; BRCA1; PHIP; TRIM29; SAP30; BASP1; DNAJC2; MAGED1; KLF10; ZZZ3; MTDH; ELF2; ERBB4; CCDC59; TLE4; XBP1; TOB1; CREB3; BRIP1; PQBP1; MDM2; USP22; ZNF623; E2F8; ARID5A; POU4F1; C1D; NFAT5; CCNC; NFE2L1; ZNF443; SMAD2; ZMYM2; NR4A1; PAWR; TEAD1; CBX3; BPTF; SFPQ; SOX10; ZNF267; ZNF423; FOXN3; CREB1; ZNF12; ING2; DEK; NR4A2; JUN; ZNF148; GTF3A; DMTF1; HMGN3; TFAP2C; PAX5; TOX; ATF3; ID3; PITX2; RNF138; PATZ1; HDAC6; ATF2; LEF1; PMS1; PSMD9; NUP62; FUBP1; SMAD1; BHLHE41; ELF5; ZBTB20; FHL2; MYBL1; BCL10; RBBP8; HMGB2; NFIB; AHR; NR1D2; PHF20; TLE1; CDK7; SNAI2; ZBTB18; ZNF217; HOXC10; GATA6; TRIB3
Down-regulation	92	CRK; FOXO3; MAF; RHOA; ABL1; TP53; NFATC1; NFIL3; NOC2L; ARNTL2; NFKBIA; ASH1L; ZNF787; TBP; TTF1; DDX17; CARHSP1; UBE2I; KLF7; TRIM25; MYBL2; MAFF; KMT2B; TCEB2; TAF12; RUVBL1; PBX3; SND1; SLC2A4RG; PITX1; NR0B2; ZNF671; LHX2; YBX3; PCGF2; TFEC; ZNF264; FOXD1; ZNF8; ZNF136; NFE2L3; ERG; E2F2; FOXL2; ZNF516; C1QBP; HIPK2; JUND; LHX6; ZNF544; ZKSCAN1; MAFG; DACH1; ZNF302; NFE2; ZNF93; HSBP1; KDM5B; KLF1; HDAC4; SIAH2; CALR; TBPL1; INSM1; BTG1; PDLIM1; MAFB; ID1; RBPJ; FOXO1; NR2F2; MXI1; LITAF; EMX2; HMGB3; CSDE1; MSX1; PAX6; EYA2; FLNA; AR; HHEX; TOX3; ZIC1; FOXF1; HEY1; SMARCA2; ESR1; IRF6; MYB; ATF5; MTA1