Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66105	Proxymetacaine	GSE92742	NPC	Human	24h	10uM	EID0364

Response Information :

Types	Number	Response transcription factors
Up-regulation	86	KLF9; NPAS2; RRN3; ZBED4; THAP1; MITF; SKIL; EHF; RBFOX2; MBD2; CRK; MYT1L; MTF2; EGR3; RB1; HIPK1; CDK2; MEIS2; PHIP; MAFF; SOX17; NR3C2; MAFB; SMAD2; EGR2; GMNN; ZKSCAN1; SMAD4; RARA; THAP10; ZNF423; HOXD1; TRIM22; IRF9; ZNF267; ZFPM2; MYBL1; ZNF329; HHEX; AHR; NFAT5; TFAP2A; PIR; STAT6; PAWR; WWP1; KLF10; ELF1; SOX10; ZZZ3; ZNF91; WWTR1; ATF2; ZNF264; IFI16; ERG; FOSB; HLF; TOX; SAP30; RAD21; TFAP2C; NFIB; BCL10; LITAF; WWC1; ELF5; HDAC9; SNAI2; TTF2; RBPMS; ZBTB16; DMTF1; ZSCAN18; GATA6; NFE2L2; PHF20; HDAC6; CREBL2; TRIB3; FOXF1; CITED2; HMGB2; ZNF217; IRF6; NR2F6
Down-regulation	63	SOX4; PUF60; DNMT3B; JARID2; POU5F1B; MDFI; CARHSP1; DRAP1; GLI2; TBP; KDM5B; DEAF1; APBB1; ZNF783; HMGB3; SIX2; MMS19; ENO1; BTG1; WIZ; TP53; MXD1; ZNF408; ELK1; WHSC1; MYCN; SREBF1; ASCL1; HSBP1; IRX5; DBP; CEBPG; ZBTB18; CITED1; KDM2A; YBX3; AFF1; BCL11B; PBX3; EDF1; TBX3; ZNF302; BRD8; TCF4; PCGF2; URI1; ID1; PRRX2; HOXC6; RERE; RYBP; DLX2; TAF1D; MSX1; MAGED1; FLNA; TOX3; AR; HOXC10; NCOA1; KDM5D; PAX6; SSBP2