Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66087	Brimonidine	GSE92742	NPC	Human	24h	10uM	EID0364

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	MEF2C; HOXD1; ZNF141; ZNF232; TRPS1; SPDEF; CEBPD; NFATC4; TAF9; ZNF623; ZNF816; RNF2; SUMO1; ZNF682; BNC1; ZNF675; TBX5; KLF9; TP73; ZFP69B; FOXK2; E2F5; ZNF345; NCOA3; PEG3; ERBB4; ZNF665; CARF; TFAP2C; HBP1; CREB1; ZNF273; CDIP1; VPS72; DACH1; NFATC3; PRDM12; ZNF415; ZNF117; CUX2; MEIS2; PEX14; CBX4; NPAS2; HOXD3; MYBL1; ZEB1; TSHZ2; MDM2; VDR; SOX18; MED7; JUP; ETS1; FOXF2; POLR3C; CREM; PAWR; AEBP1; SOHLH2; ZFPM2; ZHX2; TBX1; NR1H2; FOXE1; RAD21; ZNF611; TEAD4; ZNF107; PCGF3; MED14; BCL11A; NR5A2; L3MBTL1; TCEA2; BARX1; ZNF83; PHIP; TRIB3; TAL1; SOX13; ZNF573; YEATS4; PRDM14; NR4A2; CBFA2T3; PRDM10; ST18; BACH2; ZNF43; CAMTA1; NR1H4; CEBPG; TFAP2A; ZNF667; ZNF331; CEBPB; SIX3; TCFL5; ZBED2; IRF9; FOXN3; JUNB; KLF11; SNAI2; GATA6; ZBTB20; WT1; ZNF532; TGFB1; EN1; DDIT3; EMX2; IFI16; KLF10; IRF6; CCNH; EHF; MYRF; DMTF1; ZNF131; RYBP; TTF2; YAP1; POU2AF1; SOX10; SMAD1; NFE2; SOX17; ZSCAN18; ATF5; CDK7; HLF; FOXG1; HDAC9; TWIST1; ZNF217; ESR1; NR2F6
Down-regulation	222	JARID2; FOXO3; TAF10; SMARCA4; TRIM28; PCGF2; USF2; BRD2; DDX54; ING1; DNAJC1; KAT7; KAT5; TRIM27; NEDD8; PUF60; RXRB; ARID4B; SOX4; TCERG1; TBP; NR2F2; SUV39H1; HDAC1; LITAF; ZNF384; YBX1; ZMIZ2; TTF1; CARHSP1; NPM1; RBBP4; HSF2; NFKBIA; PHF1; BRD8; ABL1; BRPF1; PREB; ZNF274; SNIP1; FOXJ3; SMARCD1; UIMC1; BRF2; MAF; SFPQ; RFX5; NELFB; ZBTB24; TP53; CNOT1; EP400; PATZ1; BCLAF1; CENPF; HMGA2; MYCBP; RUVBL2; ETV5; ERCC3; DNMT3B; REXO4; EZH2; RBM14; TRIM32; EDF1; ETV4; ZBTB48; TCF25; POU3F2; DDX5; ORC2; ATF7IP; TFEB; PHF2; SOX2; PHF8; TBPL1; LPIN2; TADA3; SFMBT1; MED24; TFEC; GTF2F1; ITGB3BP; NONO; ATF1; RHOA; MAFB; REPIN1; PSPC1; MAFF; PIR; ZNF263; FLNA; MED23; KDM5A; ARID1A; CTNNB1; TOX3; BAZ2B; BATF3; ELF1; SCMH1; CBFB; ING3; SNW1; KDM5D; GABPB1; TBL1XR1; STAT5B; HOXC4; DEAF1; BASP1; MAGED1; FOXD1; MED6; EYA2; SMARCE1; ZNF266; ZBTB1; PSIP1; OLIG2; ZNF410; PIAS2; ELK1; HSBP1; E2F2; NFKB1; SMARCC1; BAZ1A; TRIP6; NCOA4; ZNF672; SMARCA5; ZNF45; BRD3; RBBP7; STAT6; MLX; TCF12; NUP62; TRIM16; ZBTB18; PMF1; AFF1; MSX1; PTTG1; HEY2; HOXB7; COPS2; POLR2A; USP22; ISL1; MED1; HDAC6; ASH2L; TRRAP; ENO1; CITED1; MEIS1; PFDN5; PITX1; SREBF2; ZEB2; SMAD6; PCBD1; EED; CRY1; MYCN; ZNF32; HOXB6; KDM5B; FOXO1; CREG1; FOXC1; KDM2A; CXXC1; SIAH2; HDAC2; ELK3; CHD9; NRIP1; TLE4; SP3; SALL1; VGLL4; TSC22D2; CTR9; PA2G4; ZNF516; HMGA1; TSC22D1; ARID5B; HOXC6; SAP18; BTG1; STAT1; NKX2-2; HLTF; RERE; ECD; SAFB2; TGFB1I1; BMI1; INSM1; SMARCA2; SMAD7; NKX3-1; MNAT1; ZMYM2; PHF20; KLF2; ASCL1; ERBB2; HOXA5; ID2; ID4; TBX2; SMAD3; MTA1