Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID66075	Semaxanib	GSE92742	NPC	Human	24h	10uM	EID0364

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	RBFOX2; NFATC4; ZNF232; EGR2; ZNF140; ZBED4; HOXD1; MEIS2; SNAI2; SUMO1; KLF10; NR4A3; JUP; RAD21; HIPK1; ACTL6A; MAFF; TOPORS; SMAD4; EHF; NPAS2; ETS1; GATA2; RRN3; ETS2; EGR3; NR4A1; VDR; KLF9; ATF3; C1D; REL; BCL3; TFAP2A; YEATS4; IFI16; MYCL; TOX; TRPS1; DEK; IRF9; JUNB; TTF2; ZBED2; FOS; CREM; TEAD4; FOSB; GMNN; PHIP; ZNF331; NFYB; ZZZ3; NR2F1; MKL2; ATF2; CBX3; SOX17; JUN; NAB1; TGFB1I1; NR5A2; MECOM; ZNF665; ZNF589; AHR; ZNF512B; HDAC9; STAT6; GATA6; CEBPB; TGFB1; DDIT3; TRIM29; VPS72; CREBL2; IRF6; ZNF91; PEG3; HOXB2; ELF5; HMGB2; TFAP2C; FOXG1; CREB1; NR4A2; ST18; SMAD7; ISL1; ZSCAN18; ZNF12; BHLHE41; INSM1; KLF5; WT1; TRIB3; ZNF217; TWIST1; LEF1; ZNF131; NR2F6
Down-regulation	85	SOX4; DNAJC1; GLI2; PUF60; CARHSP1; TBP; TAF10; JARID2; RHOA; DRAP1; RBBP4; TCF15; UIMC1; TAF12; ATF7IP; ENO1; MXD4; NR2F2; NFKBIA; BRD2; PSPC1; MMS19; KMT2A; AFF1; ZBTB1; USF2; MED16; TP53; HDAC3; SOX2; HSBP1; WHSC1; DDX5; ARID4B; TSC22D4; DEAF1; OLIG2; BRD8; KDM5A; ZNF22; BTG1; DDX17; GATAD2A; CENPF; IRX5; THRAP3; HLTF; KAT7; CREBZF; TAF1D; FOXD1; BCLAF1; KDM5B; EDF1; AATF; MYCN; TFDP2; PATZ1; ZNF692; TCEB2; SALL1; PTTG1; MSX1; KAT6B; CREB3L2; NFE2L1; NCOA4; ZNF652; PCGF2; ZNF32; ASCL1; HOXC6; ZBTB18; VGLL4; SP110; MAGED1; TXNIP; GABPB1; ECD; HMGB3; ERBB2; HOXB7; NRIP1; ID1; KLF2